Search Results - "Death, Alison K."

High glucose alters matrix metalloproteinase expression in two key vascular cells: potential impact on atherosclerosis in diabetes by Death, Alison K., Fisher, Elizabeth J., McGrath, Kristine C.Y., Yue, Dennis K.

“…Diabetes is a major risk factor for atherosclerosis. Hyperglycemia is an underlying contributing factor; however, the mechanisms that mediate the vascular…”
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Androgens and Cardiovascular Disease by Liu, Peter Y, Death, Alison K, Handelsman, David J

“…Globally, cardiovascular disease will continue causing most human deaths for the foreseeable future. The consistent gender gap in life span of approximately…”
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Effects of glucose on matrix metalloproteinase and plasmin activities in mesangial cells: Possible role in diabetic nephropathy by Mclennan, Susan V., Fisher, Elizabeth, Martell, Sally Y., Death, Alison K., Williams, Paul F., Lyons, J. Guy, Yue, Dennis K.

“…Effects of glucose on matrix metalloproteinase and plasmin activities in mesangial cells: Possible role in diabetic nephropathy. Diabetic nephropathy is…”
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Cardiovascular disease in diabetic nephropathy patients: cell adhesion molecules as potential markers? by Wu, Ted, McGrath, Kristine C Y, Death, Alison K

“…Cardiovascular disease is a major complication of diabetes mellitus, especially for patients with diabetic nephropathy. The underlying factor or pathogenic…”
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Dihydrotestosterone Promotes Vascular Cell Adhesion Molecule-1 Expression in Male Human Endothelial Cells via a Nuclear Factor-κB-Dependent Pathway by Death, Alison K, McGrath, Kristine C. Y, Sader, Mark A, Nakhla, Shirley, Jessup, Wendy, Handelsman, David J, Celermajer, David S

“…There exists a striking gender difference in atherosclerotic vascular disease. For decades, estrogen was considered atheroprotective; however, an alternative…”
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Tetrahydrogestrinone Is a Potent Androgen and Progestin by Death, Alison K., McGrath, Kristine C. Y., Kazlauskas, Rymantas, Handelsman, David J.

“…Tetrahydrogestrinone (THG) was recently identified as a novel steroid used illicitly to improve athletic performance. Although its structure is closely related…”
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Androgens up-regulate atherosclerosis-related genes in macrophages from males but not females: Molecular insights into gender differences in atherosclerosis by NG, Martin K. C, QUINN, Carmel M, MCCROHON, Jane A, NAKHLA, Shirley, JESSUP, Wendy, HANDELSMAN, David J, CELERMAJER, David S, DEATH, Alison K

“…This study investigated the effects of androgens on gene expression in male- and female-donor macrophages. Men have more severe coronary disease than women…”
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TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer by SUNDE, Margaret, MCGRATH, Kristine C. Y, YOUNG, Lei, MATTHEWS, Jacqueline M, CHUA, Elizabeth L, MACKAY, Joel P, DEATH, Alison K

“…A novel gene, thyroid cancer 1 (TC-1), was found recently to be overexpressed in thyroid cancer. TC-1 shows no homology to any of the known thyroid…”
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Competitive RT-PCR for measuring metalloproteinase gene expression in human mesangial cells exposed to a hyperglycemic environment by Death, A K, Yue, D K, Turtle, J R

“…Competitive reverse transcription (RT)-PCR is now considered a reliable technique for determining the relative or absolute copy number of target mRNAs in…”
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Androgen receptor expression is greater in macrophages from male than from female donors : A sex difference with implications for atherogenesis by MCCROHON, J. A, DEATH, A. K, NAKHLA, S, JESSUP, W, HANDELSMAN, D. J, STANLEY, K. K, CELERMAJER, D. S

“…Male sex is an independent risk factor for the extent and severity of atherosclerosis. The influence of androgens on foam cell formation, a key event in…”
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Valproate is an anti-androgen and anti-progestin by Death, Alison K., McGrath, Kristine C.Y., Handelsman, David J.

“…Anti-convulsant treatment is associated with a high prevalence of reproductive dysfunction compared with age-matched non-epileptics. We examined the widely…”
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Androgen receptor gene expression in leucocytes is hormonally regulated: implications for gender differences in disease pathogenesis by Sader, Mark A., McGrath, Kristine C. Y., Hill, Michelle D., Bradstock, Ken F., Jimenez, Mark, Handelsman, David J., Celermajer, David S., Death, Alison K.

“…Summary Objective  There is evidence that male sex hormones influence the rate of progression of inflammatory and cardiovascular diseases. We have previously…”
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Nitroglycerin upregulates matrix metalloproteinase expression by human macrophages by Death, Alison K, Nakhla, Shirley, McGrath, Kristine C.Y, Martell, Sally, Yue, Dennis K, Jessup, Wendy, Celermajer, David S

“…This study aimed to determine whether nitroglycerin (NTG) treatment affects matrix metalloproteinase (MMP) gene expression and activities in human macrophages…”
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Tetrahydrogestrinone is a Potent Androgen and Progestin by Death, Alison K, McGrath, Kristine C. Y, Kazlauskas, Rymantas, Handelsman, David J

“…Tetrahydrogestrinone (THG) is a recently discovered steroid that has never been marketed and is used unlawfully to enhance sports performance. Structurally,…”
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Dihydrotestosterone promotes vascular cell adhesion molecule-1 expression in male human endothelial cells via a nuclear factor-kappaB-dependent pathway by Death, Alison K, McGrath, Kristine C Y, Sader, Mark A, Nakhla, Shirley, Jessup, Wendy, Handelsman, David J, Celermajer, David S

“…There exists a striking gender difference in atherosclerotic vascular disease. For decades, estrogen was considered atheroprotective; however, an alternative…”
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Androgens Up-Regulate Atherosclerosis-Related Genes in Macrophages From Males But Not Females by Ng, Martin K.C, Quinn, Carmel M, McCrohon, Jane A, Nakhla, Shirley, Jessup, Wendy, Handelsman, David J, Celermajer, David S, Death, Alison K

“…This study investigated the effects of androgens on gene expression in male- and female-donor macrophages. Men have more severe coronary disease than women…”
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The Effect of High Glucose on Vascular Cell Expression of Cellular Adhesion Molecules and Metalloproteinases by DEATH, ALISON K, WU, TED, CHAN, KRISTINE C. Y, NAKHLA, SHIRLEY, YUE, DENNIS K

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Repetitive hypoxia decreases matrix metalloproteinase activity in human monocyte derived macrophages by Lattimore, Jo-Dee L., Wilcox, Ian, McGrath, Kris, Nakhla, Shirley, Celermajer, David S., Death, Alison K.

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Leukocyte androgen receptor expression in mice and men; Gender and hormonal regulation, and implications for atherosclerosis by Sader, Mark A., McGrath, Kristine C.Y., Handelsman, David J., Celermajer, David S., Death, Alison K.

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Androgen exposure increases human monocyte adhesion to vascular endothelium via Up-regulation of VCAM-1 expression in a gender specific manner by McGrath, Kristine C.Y., Sader, Mark A., Nakhla, Shirley, Handelsman, David J., Celermajer, David S., Death, Alison K.

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