Search Results - "Dearlove, Bethany L"
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Rapid host switching in generalist Campylobacter strains erodes the signal for tracing human infections
Published in The ISME Journal (01-03-2016)“…Campylobacter jejuni and Campylobacter coli are the biggest causes of bacterial gastroenteritis in the developed world, with human infections typically arising…”
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Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features
Published in Nature communications (11-03-2024)“…In the ENSEMBLE randomized, placebo-controlled phase 3 trial (NCT04505722), estimated single-dose Ad26.COV2.S vaccine efficacy (VE) was 56% against moderate to…”
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Measuring Asymmetry in Time-Stamped Phylogenies
Published in PLoS computational biology (01-07-2015)“…Previous work has shown that asymmetry in viral phylogenies may be indicative of heterogeneity in transmission, for example due to acute HIV infection or the…”
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4
Genotype-Specific Evolution of Hepatitis E Virus
Published in Journal of virology (01-05-2017)“…Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis globally. HEV comprises four genotypes with different geographic distributions and…”
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US National Institutes of Health Prioritization of SARS-CoV-2 Variants
Published in Emerging infectious diseases (01-05-2023)“…Since late 2020, SARS-CoV-2 variants have regularly emerged with competitive and phenotypic differences from previously circulating strains, sometimes with the…”
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Defining the risk of SARS-CoV-2 variants on immune protection
Published in Nature (London) (26-05-2022)“…The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants jeopardizes the protective antiviral immunity induced after…”
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Quantifying the Aftermath: Recent Outbreaks Among People Who Inject Drugs and the Utility of Phylodynamics
Published in The Journal of infectious diseases (25-05-2018)Get full text
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Timing HIV infection with a simple and accurate population viral dynamics model
Published in Journal of the Royal Society interface (01-06-2021)“…Clinical trials for HIV prevention can require knowledge of infection times to subsequently determine protective drug levels. Yet, infection timing is…”
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HIV-1 infections with multiple founders associate with the development of neutralization breadth
Published in PLoS pathogens (01-03-2022)“…Eliciting broadly neutralizing antibodies (bnAbs) is a cornerstone of HIV-1 vaccine strategies. Comparing HIV-1 envelope (env) sequences from the first weeks…”
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10
Biased phylodynamic inferences from analysing clusters of viral sequences
Published in Virus evolution (01-07-2017)“…Abstract Phylogenetic methods are being increasingly used to help understand the transmission dynamics of measurably evolving viruses, including HIV. Clusters…”
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SARS-CoV-2 variant replacement constrains vaccine-specific viral diversification
Published in Virus evolution (09-10-2024)“…Abstract Coronavirus disease 2019 (COVID-19) vaccine breakthrough infections have been important for all circulating severe acute respiratory syndrome…”
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Whole genome sequencing and de novo assembly identifies Sydney-like variant noroviruses and recombinants during the winter 2012/2013 outbreak in England
Published in Virology journal (13-11-2013)“…BACKGROUND: Norovirus is the commonest cause of epidemic gastroenteritis among people of all ages. Outbreaks frequently occur in hospitals and the community,…”
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Measuring Asymmetry in Time-Stamped Phylogenies: e1004312
Published in PLoS computational biology (01-07-2015)“…Previous work has shown that asymmetry in viral phylogenies may be indicative of heterogeneity in transmission, for example due to acute HIV infection or the…”
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14
Rapid host switching in generalist Campylobacter strains erodes the signal for tracing human infections
Published 07-04-2015“…Campylobacter jejuni and Campylobacter coli are the biggest causes of bacterial gastroenteritis in the developed world, with human infections typically arising…”
Get full text
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