Search Results - "Deardorff, William James"
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Behavioral and psychological symptoms in Alzheimer's dementia and vascular dementia
Published in Handbook of clinical neurology (2019)“…Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent and represent a significant burden for patients and their caregivers. Early…”
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The Use of Cholinesterase Inhibitors Across All Stages of Alzheimer’s Disease
Published in Drugs & aging (01-07-2015)“…Current pharmacological therapy for Alzheimer’s disease (AD) includes the cholinesterase inhibitors (ChEIs) donepezil, rivastigmine, and galantamine and the N…”
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Fingerstick glucose monitoring by cognitive impairment status in Veterans Affairs nursing home residents with diabetes
Published in Journal of the American Geriatrics Society (JAGS) (01-11-2022)“…Background Guidelines recommend nursing home (NH) residents with cognitive impairment receive less intensive glycemic treatment and less frequent fingerstick…”
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A review of the clinical efficacy, safety and tolerability of the antidepressants vilazodone, levomilnacipran and vortioxetine
Published in Expert opinion on pharmacotherapy (01-12-2014)“…As a leading cause of disability, major depressive disorder (MDD) is characterized by reduced quality of life and altered functioning. Current pharmaceutical…”
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Pharmacotherapeutic strategies in the treatment of severe Alzheimer's disease
Published in Expert opinion on pharmacotherapy (01-09-2016)“…Alzheimer's disease (AD) is a slowly progressive neurodegenerative disease. Patients with severe AD often require assistance with daily functioning and have a…”
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Do functional status and Medicare claims data improve the predictive accuracy of an electronic health record mortality index? Findings from a national Veterans Affairs cohort
Published in BMC geriatrics (18-05-2022)“…Electronic health record (EHR) prediction models may be easier to use in busy clinical settings since EHR data can be auto-populated into models. This study…”
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Time to Benefit of Bisphosphonate Therapy for the Prevention of Fractures Among Postmenopausal Women With Osteoporosis: A Meta-analysis of Randomized Clinical Trials
Published in JAMA internal medicine (01-01-2022)“…The clinical decision to initiate bisphosphonate therapy for the treatment of osteoporosis requires balancing shorter-term harms and burdens (eg,…”
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Mild cognitive impairment as a clinical and research outcome: Ready for prime time?
Published in Journal of the American Geriatrics Society (JAGS) (01-05-2022)“…This editorial comments on the article by Gaussoin et al. in this issue…”
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Targeting neuroinflammation in Alzheimer's disease: evidence for NSAIDs and novel therapeutics
Published in Expert review of neurotherapeutics (02-01-2017)“…There is an increasing recognition of the immune system as an important mediator in the pathogenesis of Alzheimer's disease (AD). As immune system modulators,…”
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Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia-Reply
Published in JAMA internal medicine (01-05-2023)Get more information
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Safety and clinical effects of EVP-6124 in subjects with Alzheimer's disease currently or previously receiving an acetylcholinesterase inhibitor medication
Published in Expert review of neurotherapeutics (01-01-2015)“…Alzheimer's disease (AD) is a prevalent and currently incurable brain disease whose impact will continue to rise as the population ages. With limited treatment…”
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COVID-19, masks, and hearing difficulty: Perspectives of healthcare providers
Published in Journal of the American Geriatrics Society (JAGS) (01-10-2021)Get full text
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Association of Sensory and Cognitive Impairment With Healthcare Utilization and Cost in Older Adults
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2019)“…OBJECTIVES To examine the association between self‐reported vision impairment (VI), hearing impairment (HI), and dual‐sensory impairment (DSI), stratified by…”
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A fixed-dose combination of memantine extended-release and donepezil in the treatment of moderate-to-severe Alzheimer's disease
Published in Drug design, development and therapy (01-01-2016)“…Currently available therapies for the treatment of Alzheimer's disease (AD) consist of cholinesterase inhibitors (ChEIs), such as donepezil, and the…”
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Efficacy of rivastigmine tartrate, transdermal system, in Alzheimer's disease
Published in Expert opinion on pharmacotherapy (12-04-2016)“…As the most common major neurocognitive disorder, Alzheimer's disease (AD) will play an increasingly important role both socially and financially as the…”
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The Pharmacology and Clinical Use of the Antidepressants Vilazodone, Levomilnacipran, and Vortioxetine for Depression in the Elderly
Published in Current geriatrics reports (01-12-2015)“…Treatment of depression in the elderly is particularly challenging due to the relative scarcity of well-designed trials, atypical clinical presentations, and…”
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