Search Results - "Dearden, Helen"

Combined ipilimumab and nivolumab first‐line and after BRAF‐targeted therapy in advanced melanoma by Mason, Robert, Dearden, Helen C., Nguyen, Bella, Soon, Jennifer A., Smith, Jessica Louise, Randhawa, Manreet, Mant, Andrew, Warburton, Lydai, Lo, Serigne, Meniawy, Tarek, Guminski, Alexander, Parente, Phillip, Ali, Sayed, Haydon, Andrew, Long, Georgina V., Carlino, Matteo S., Millward, Michael, Atkinson, Victoria G., Menzies, Alexander M.

“…The combination of ipilimumab and nivolumab is a highly active systemic therapy for metastatic melanoma but can cause significant toxicity. We explore the…”
Get full text

Observational study investigating Tolerance Of Anticancer Systemic Therapy In the Elderly (TOASTIE): a protocol by Dearden, Helen, Baxter, Mark A, Martin, Sally, Rowe, Michael, Zucker, Kieran, Jones, Christopher Mark, Olsson-Brown, Anna C, Petty, R D, Swinson, Daniel, Brunner, Clair, Smith, Fiona, Lewis, Anna, Taylor, Sarah, Rodgers, Lisa, Cree, Anthea, Smith, Eleanor

“…IntroductionThe number of older adults diagnosed with cancer is increasing. Older adults are more likely to have pre-existing frailty, which is associated with…”
Get full text

UK national observational cohort study investigating Tolerance of Anti-cancer Systemic Therapy in the Elderly: the TOASTIE study by Baxter, Mark A, Rowe, Michael, Zucker, Kieran, Peters, Adam L, Rohan, Maria, Marsh, Alexandra, Gee, Abigail L, Quesne, Gemma, Heseltine, Jonny, Prichard, Rachel, Scott, Deborah, O'Neill, Conor, Brunner, Clair, Howells, Joni, Conteh, Veronica, Aujayeb, Avinash, Yan, Xiangfei, Rodgers, Lisa J, Martin, Sally, Dearden, Helen, Grech, J, Hannington, L, McInerney, S, Kingdon, S, Ali, H, Eastlake, L, Park, S, Bryce, R, Parslow, D, Cope, V, Hamilton, J, Clements, G, Aziz, N, Platt, J, Heywood, R

“…ObjectiveThe Cancer and Aging Research Group (CARG) score was developed to predict severe chemotherapy-induced toxicity risk in older adults; validation study…”
Get full text

A phase II trial of cemiplimab alone or in combination with standard of care chemotherapy in locally advanced or metastatic penile carcinoma (EPIC trial) by Bahl, Amit, Foulstone, Emily, Ashurst, Lauren, Renninson, Emily, White, Paul, Bravo, Alicia, Afshar, Mehran, Alifrangis, Constantine, Venugopal, Balaji, Thomson, Alastair, Tran, Anna, Barber, Jim, Dearden, Helen Clare, Kent, Christopher, Kumar, Vivekanandan, Callaway, Mark, Challapalli, Amarnath

“…TPS14 Background: Penile cancer is rare, <1% of male malignancies diagnosed each year, but its incidence is increasing with an 18% increase over the last…”
Get full text

Hyperacute toxicity with combination ipilimumab and anti-PD1 immunotherapy by Dearden, Helen, Au, Lewis, Wang, Daniel Y., Zimmer, Lisa, Eroglu, Zeynep, Smith, Jessica L., Cuvietto, Marcello, Khoo, Chloe, Atkinson, Victoria, Lo, Serigne, Long, Georgina V., Sandhu, Shahneen, Ascierto, Paolo A., Carlino, Matteo S., Johnson, Douglas B., Larkin, James, Menzies, Alexander M.

“…Combination ipilimumab and nivolumab is approved for several malignancies. Toxicity most often occurs 6–10 weeks into treatment. Whether very early toxicity is…”
Get full text

The Effect of Immune Checkpoint Inhibitors in Patients with Concomitant Advanced Melanoma and Chronic Lymphocytic Leukaemia by Tobin, Joshua W.D., Royle, Jane, Mason, Robert, Michael, Millward, Lydia, Warburton, Sandhu, Shahneen, Haydon, Andrew, Long, Georgina, Carlino, Matteo, Smith, Jessica L, Dearden, Helen, Mollee, Peter, Gill, Devinder, Mapp, Sally, Atkinson, Victoria, Keane, Colm

“…Immune checkpoint inhibitors (ICI's) have revolutionized the management of patients with advanced melanoma (AM). However, the data on the effectiveness of…”
Get full text

Hyperacute toxicity with combination ipilimumab (ipi) and anti-PD1 immunotherapy by Dearden, Helen Clare, Au, Lewis, Wang, Daniel Ying, Zimmer, Lisa, Eroglu, Zeynep, Smith, Jessica Louise, Curvietto, Marcello, Khoo, Chloe, Atkinson, Victoria, Lo, Serigne, Guminski, Alexander, Long, Georgina V., Sandhu, Shahneen Kaur, Ascierto, Paolo Antonio, Carlino, Matteo S., Johnson, Douglas Buckner, Larkin, James M. G., Menzies, Alexander M.

“…Abstract only…”
Get full text