Search Results - "Deans, A."

Prehabilitation Before Major Abdominal Surgery: A Systematic Review and Meta-analysis by Hughes, Michael J., Hackney, Rosie J., Lamb, Peter J., Wigmore, Stephen J., Christopher Deans, D. A., Skipworth, Richard J. E.

“…Introduction Prehabilitation prior to major surgery has increased in popularity over recent years and aims to improve pre-operative conditioning of patients to…”
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Dietary Management of Chronic Kidney Disease and Secondary Hyperoxaluria in Patients with Short Bowel Syndrome and Type 3 Intestinal Failure by Adler, Maciej, Millar, Ewen C, Deans, Kevin A, Torreggiani, Massimo, Moroni, Francesca

“…Short gut syndrome can lead to type 3 intestinal failure, and nutrition and hydration can only be achieved with parenteral nutrition (PN). While this is a…”
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Relationship between Pharmacokinetics and Pharmacodynamic Responses in Healthy Smokers Informs a Once-Daily Dosing Regimen for Nemiralisib by Begg, M, Wilson, R, Hamblin, J N, Montembault, M, Green, J, Deans, A, Amour, A, Worsley, S, Fantom, K, Cui, Y, Dear, G, Ahmad, S, Kielkowska, A, Clark, J, Boyce, M, Cahn, A, Hessel, E M

“…Nemiralisib (GSK2269557), a potent inhaled inhibitor of phosphoinositide 3-kinase (PI3K ), is being developed for the treatment of respiratory disorders…”
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Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort by Shiels, Paul G, McGlynn, Liane M, MacIntyre, Alan, Johnson, Paul C D, Batty, G David, Burns, Harry, Cavanagh, Jonathan, Deans, Kevin A, Ford, Ian, McConnachie, Alex, McGinty, Agnes, McLean, Jennifer S, Millar, Keith, Sattar, Naveed, Tannahill, Carol, Velupillai, Yoga N, Packard, Chris J

“…It has previously been hypothesized that lower socio-economic status can accelerate biological ageing, and predispose to early onset of disease. This study…”
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Author’s Reply: Prehabilitation Before Major Abdominal Surgery by Hughes, Michael J., Hackney, Rosie J., Lamb, Peter J., Wigmore, Stephen J., Deans, D. A. Christopher, Skipworth, Richard J. E.

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Systematic Review and Meta-Analysis of Epidural Analgesia Versus Different Analgesic Regimes Following Oesophagogastric Resection by Hughes, Michael, Yim, Ivan, Deans, D. A. Christopher, Couper, Graeme W., Lamb, Peter J., Skipworth, Richard J. E.

“…Introduction Effective analgesia following open oesophagogastric (OG) resection is considered a key determinant of recovery. This review aimed to compare…”
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Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? by Miller, Ashley M, Purves, David, McConnachie, Alex, Asquith, Darren L, Batty, G David, Burns, Harry, Cavanagh, Jonathan, Ford, Ian, McLean, Jennifer S, Packard, Chris J, Shiels, Paul G, Turner, Helen, Velupillai, Yoga N, Deans, Kevin A, Welsh, Paul, McInnes, Iain B, Sattar, Naveed

“…Preliminary data mostly from animal models suggest the sST2/IL-33 pathway may have causal relevance for vascular disease and diabetes and thus point to a…”
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An investigation of two-dimensional ultrasound carotid plaque presence and intima media thickness in middle-aged South Asian and European men living in the United kingdom by Ghouri, Nazim, Purves, David, Deans, Kevin A, Logan, Greig, McConnachie, Alex, Wilson, John, Gill, Jason M R, Sattar, Naveed

“…Ultrasound studies of carotid intima media thickness (cIMT) and plaques are limited in South Asians, a group at elevated cardiovascular disease (CVD) risk. We…”
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Early life socioeconomic adversity is associated in adult life with chronic inflammation, carotid atherosclerosis, poorer lung function and decreased cognitive performance: a cross-sectional, population-based study by Packard, Chris J, Bezlyak, Vladimir, McLean, Jennifer S, Batty, G David, Ford, Ian, Burns, Harry, Cavanagh, Jonathan, Deans, Kevin A, Henderson, Marion, McGinty, Agnes, Millar, Keith, Sattar, Naveed, Shiels, Paul G, Velupillai, Yoga N, Tannahill, Carol

“…Socioeconomic gradients in health persist despite public health campaigns and improvements in healthcare. The Psychosocial and Biological Determinants of…”
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Personality, socio-economic status and inflammation: cross-sectional, population-based study by Millar, Keith, Lloyd, Suzanne M, McLean, Jennifer S, Batty, G David, Burns, Harry, Cavanagh, Jonathan, Deans, Kevin A, Ford, Ian, McConnachie, Alex, McGinty, Agnes, Mõttus, Réne, Packard, Chris J, Sattar, Naveed, Shiels, Paul G, Velupillai, Yoga N, Tannahill, Carol

“…Associations between socio-economic status (SES), personality and inflammation were examined to determine whether low SES subjects scoring high on neuroticism…”
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Clinical prognostic scoring system to aid decision-making in gastro-oesophageal cancer by Deans, D. A. C., Wigmore, S. J., de Beaux, A. C., Paterson-Brown, S., Garden, O. J., Fearon, K. C. H.

“…Background: Accurate prediction of prognosis in gastro‐oesophageal cancer remains challenging. The aim of this study was to develop a robust model for outcome…”
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Nutrition as a neglected factor in insect herbivore susceptibility to Bt toxins by Deans, CA, Sword, GA, Behmer, ST

“…[Display omitted] •Bt resistance management assumes that resistance is solely due to genetic factors.•Environmental factors can mediate phenotypic plasticity…”
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mRNA profiling of the cancer degradome in oesophago–gastric adenocarcinoma by Baren, J P, Stewart, G D, Stokes, A, Gray, K, Pennington, C J, O'Neill, R, Deans, D A C, Paterson-Brown, S, Riddick, A C P, Edwards, D R, Fearon, K C H, Ross, J A, Skipworth, R J E

“…Background: Degradation of the extracellular matrix is fundamental to tumour development, invasion and metastasis. Several protease families have been…”
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Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2α may signal skeletal muscle atrophy in weight-losing cancer patients by Eley, H L, Skipworth, R J E, Deans, D A C, Fearon, K C H, Tisdale, M J

“…Previous studies suggest that the activation (autophosphorylation) of dsRNA-dependent protein kinase (PKR) can stimulate protein degradation, and depress…”
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Macronutrient regulation in adult spotted‐wing Drosophila and nutritional impacts on susceptibility to three commonly‐used insecticides by Deans, Carrie A., Hutchison, William D.

“…Abstract Nutrition provides the resources necessary to carry out all the physiological functions organisms require. This has important implications for insect…”
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Quantity versus quality: Effects of diet protein-carbohydrate ratios and amounts on insect herbivore gene expression by Deans, Carrie A., Sword, Gregory A., Vogel, Heiko, Behmer, Spencer T.

“…Dietary protein and digestible carbohydrates are two key macronutrients for insect herbivores, but the amounts and ratios of these two macronutrients in plant…”
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Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy by Deans, DA Chris, Tan, Benjamin HL, Ross, James A, Rose-Zerilli, Matthew, Wigmore, Stephen J, Howell, W. Martin, Grimble, Robert F, Fearon, Kenneth CH

“…BACKGROUND: The genetic predisposition of the host to local or systemic inflammation may contribute to the effect of cancer cachexia. OBJECTIVE: We…”
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Matrix context and patch quality jointly determine diversity in a landscape‐scale experiment by Deans, Robert A., Chalcraft, David R.

“…The biodiversity of a habitat patch is predicted to be driven in part by interactions between patch quality and landscape context (i.e. type of regional…”
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Spatio-Temporal, Genotypic, and Environmental Effects on Plant Soluble Protein and Digestible Carbohydrate Content: Implications for Insect Herbivores with Cotton as an Exemplar by Deans, Carrie A., Behmer, Spencer T., Fiene, Justin, Sword, Gregory A.

“…Plant soluble protein and digestible carbohydrate content significantly affect insect herbivore fitness, but studies reporting plant protein and carbohydrate…”
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Nutrition affects insect susceptibility to Bt toxins by Deans, Carrie A., Behmer, Spencer T., Tessnow, Ashley E., Tamez-Guerra, Patricia, Pusztai-Carey, Marianne, Sword, Gregory A.

“…Pesticide resistance represents a major challenge to global food production. The spread of resistance alleles is the primary explanation for observations of…”
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