Search Results - "Dean Sherry, A"

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver by Satapati, Santhosh, Kucejova, Blanka, Duarte, Joao A G, Fletcher, Justin A, Reynolds, Lacy, Sunny, Nishanth E, He, Tianteng, Nair, L Arya, Livingston, Kenneth A, Livingston, Kenneth, Fu, Xiaorong, Merritt, Matthew E, Sherry, A Dean, Malloy, Craig R, Shelton, John M, Lambert, Jennifer, Parks, Elizabeth J, Corbin, Ian, Magnuson, Mark A, Browning, Jeffrey D, Burgess, Shawn C

“…Mitochondria are critical for respiration in all tissues; however, in liver, these organelles also accommodate high-capacity anaplerotic/cataplerotic pathways…”
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Chemical exchange saturation transfer contrast agents for magnetic resonance imaging by Sherry, A Dean, Woods, Mark

“…Magnetic resonance imaging (MRI) contrast agents have become an important tool in clinical medicine. The most common agents are Gd(3+)-based complexes that…”
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Review and consensus recommendations on clinical APT‐weighted imaging approaches at 3T: Application to brain tumors by Zhou, Jinyuan, Zaiss, Moritz, Knutsson, Linda, Sun, Phillip Zhe, Ahn, Sung Soo, Aime, Silvio, Bachert, Peter, Blakeley, Jaishri O., Cai, Kejia, Chappell, Michael A., Chen, Min, Gochberg, Daniel F., Goerke, Steffen, Heo, Hye‐Young, Jiang, Shanshan, Jin, Tao, Kim, Seong‐Gi, Laterra, John, Paech, Daniel, Pagel, Mark D., Park, Ji Eun, Reddy, Ravinder, Sakata, Akihiko, Sartoretti‐Schefer, Sabine, Sherry, A. Dean, Smith, Seth A., Stanisz, Greg J., Sundgren, Pia C., Togao, Osamu, Vandsburger, Moriel, Wen, Zhibo, Wu, Yin, Zhang, Yi, Zhu, Wenzhen, Zu, Zhongliang, Zijl, Peter C. M.

“…Amide proton transfer‐weighted (APTw) MR imaging shows promise as a biomarker of brain tumor status. Currently used APTw MRI pulse sequences and protocols vary…”
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Bimodal MR-PET Agent for Quantitative pH Imaging by Frullano, Luca, Catana, Ciprian, Benner, Thomas, Sherry, A. Dean, Caravan, Peter

“…Two unknowns: The relaxivity of activatable magnetic resonance (MR) contrast agents depends on environmental factors, such as the pH value or enzymatic…”
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A Responsive Magnetic Resonance Imaging Contrast Agent for Detection of Excess Copper(II) in the Liver In Vivo by Paranawithana, Namini N, Martins, Andre F, Clavijo Jordan, Veronica, Zhao, Piyu, Chirayil, Sara, Meloni, Gabriele, Sherry, A. Dean

“…The design, synthesis, and properties of a new gadolinium-based copper-responsive magnetic resonance imaging (MRI) contrast agent is presented. The sensor…”
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Primer on gadolinium chemistry by Sherry, A. Dean, Caravan, Peter, Lenkinski, Robert E.

“…Gadolinium is widely known by all practitioners of magnetic resonance imaging (MRI) but few appreciate the basic solution chemistry of this trivalent…”
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In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma by Sagiyama, Koji, Mashimo, Tomoyuki, Togao, Osamu, Vemireddy, Vamsidhara, Hatanpaa, Kimmo J., Maher, Elizabeth A., Mickey, Bruce E., Pan, Edward, Sherry, Dean, Bachoo, Robert M., Takahashi, Masaya

“…Glioblastoma multiforme (GBM), which account for more than 50% of all gliomas, is among the deadliest of all human cancers. Given the dismal prognosis of GBM,…”
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Imaging Tissue Physiology In Vivo by Use of Metal Ion-Responsive MRI Contrast Agents by Khalighinejad, Pooyan, Parrott, Daniel, Sherry, A Dean

“…Paramagnetic metal ion complexes, mostly based on gadolinium (Gd ), have been used for over 30 years as magnetic resonance imaging (MRI) contrast agents. Gd…”
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Basic MR relaxation mechanisms and contrast agent design by De León-Rodríguez, Luis M., Martins, André F., Pinho, Marco C., Rofsky, Neil M., Sherry, A. Dean

“…The diagnostic capabilities of magnetic resonance imaging (MRI) have undergone continuous and substantial evolution by virtue of hardware and software…”
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Hyperpolarized 15N-pyridine Derivatives as pH-Sensitive MRI Agents by Jiang, Weina, Lumata, Lloyd, Chen, Wei, Zhang, Shanrong, Kovacs, Zoltan, Sherry, A. Dean, Khemtong, Chalermchai

“…Highly sensitive MR imaging agents that can accurately and rapidly monitor changes in pH would have diagnostic and prognostic value for many diseases. Here, we…”
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Analysis of steady-state carbon tracer experiments using akaike information criteria by Alger, Jeffry R., Minhajuddin, Abu, Dean Sherry, A., Malloy, Craig R.

“…Introduction Carbon isotope tracers have been used to determine relative rates of tricarboxylic acid cycle (TCA) cycle pathways since the 1950s. Steady-state…”
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Comparison of kinetic models for analysis of pyruvate-to-lactate exchange by hyperpolarized 13C NMR by Harrison, Crystal, Yang, Chendong, Jindal, Ashish, DeBerardinis, Ralph J., Hooshyar, M. A., Merritt, Matthew, Dean Sherry, A., Malloy, Craig R.

“…The activity of specific enzyme‐catalyzed reactions may be detected in vivo by 13 C NMR of hyperpolarized (HP) substrates. The signals from HP substrates and…”
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A novel class of polymeric pH-responsive MRI CEST agents by Zhang, Shanrong, Zhou, Kejin, Huang, Gang, Takahashi, Masaya, Sherry, A Dean, Gao, Jinming

“…In this communication, we report that ionizable, tertiary amine-based block copolymers can be used as pH-responsive contrast agents for magnetic resonance…”
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MRI detection of glycogen in vivo by using chemical exchange saturation transfer imaging (glycoCEST) by van Zijl, Peter C.M, Jones, Craig K, Ren, Jimin, Malloy, Craig R, Sherry, A. Dean

“…Detection of glycogen in vivo would have utility in the study of normal physiology and many disorders. Presently, the only magnetic resonance (MR) method…”
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pH imaging of mouse kidneys in vivo using a frequency-dependent paraCEST agent by Wu, Yunkou, Zhang, Shanrong, Soesbe, Todd C., Yu, Jing, Vinogradov, Elena, Lenkinski, Robert E., Sherry, A. Dean

“…Purpose This study explored the feasibility of using a pH responsive paramagnetic chemical exchange saturation transfer (paraCEST) agent to image the pH…”
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Noninvasive MRI of β-cell function using a Zn²⁺-responsive contrast agent by Lubag, Angelo J. M., De Leon-Rodriguez, Luis M., Burgess, Shawn C., Sherry, A. Dean

“…Elevation of postprandial glucose stimulates release of insulin from granules stored in pancreatic islet β-cells. We demonstrate here that divalent zinc ions…”
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Investigations into the Signaling Pathways Involving Glucose-Stimulated Zinc Secretion (GSZS) from Prostate Epithelial Cells In Vitro and In Vivo by Parrott, Daniel, Suh, Eul Hyun, Khalighinejad, Pooyan, Jordan, Veronica Clavijo, Arreola, Ivan, Lo, Su-Tang, Sherry, A. Dean

“…Purpose Recently, we reported that exposure of prostate cells in vitro or the in vivo prostate to high glucose results in release of Zn 2+ ions, a process now…”
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A concentration-independent method to measure exchange rates in PARACEST agents by Dixon, W. Thomas, Ren, Jimin, Lubag, Angelo J. M., Ratnakar, James, Vinogradov, Elena, Hancu, Ileana, Lenkinski, Robert E., Sherry, A. Dean

“…The efficiency of chemical exchange dependent saturation transfer (CEST) agents is largely determined by their water or proton exchange kinetics, yet methods…”
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A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity by Wu, Cheng-Yang, Satapati, Santhosh, Gui, Wenjun, Wynn, R. Max, Sharma, Gaurav, Lou, Mingliang, Qi, Xiangbing, Burgess, Shawn C., Malloy, Craig, Khemtong, Chalermchai, Sherry, A. Dean, Chuang, David T., Merritt, Matthew E.

“…The pyruvate dehydrogenase complex (PDC) is a key control point of energy metabolism and is subject to regulation by multiple mechanisms, including…”
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Metabolic cycling in control of glucose-stimulated insulin secretion by Jensen, Mette V, Joseph, Jamie W, Ronnebaum, Sarah M, Burgess, Shawn C, Sherry, A Dean, Newgard, Christopher B

“…Glucose-stimulated insulin secretion (GSIS) is central to normal control of metabolic fuel homeostasis, and its impairment is a key element of beta-cell…”
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