Search Results - "Dean, Wendy L."
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Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome
Published in Nature (London) (23-10-1997)“…The gene IGF2, which encodes a fetal insulin-like growth factor, is imprinted, so only one of two parental copies of the gene is expressed. The altered…”
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The mouse Zac1 locus: basis for imprinting and comparison with human ZAC
Published in Gene (12-06-2002)“…We identified a maternally methylated CpG island at the mouse Zac1 locus on chromosome (Chr.) 10 in a screen for imprinted genes. The homologous human gene ZAC…”
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Dynamic Methylation Adjustment and Counting as Part of Imprinting Mechanisms
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-1996)“…Monoallelic expression in diploid mammalian cells appears to be a widespread phenomenon, with the most studied examples being X-chromosome inactivation in…”
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The small nuclear RNAs for pre-mRNA splicing are coordinately regulated during oocyte maturation and early embryogenesis in the mouse
Published in Development (Cambridge) (01-06-1989)“…The abundance and localization of snRNAs and snRNPs involved in processing and splicing of pre-mRNA has been studied during early mouse embryogenesis. The…”
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Haldane's rule and heterogametic female and male sterility in the mouse
Published in Genome (01-04-1994)“…Failed genetic experiments or experiments designed for other purposes sometimes reveal novel genetic information. The interspecific cross between laboratory…”
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Localization and expression of U1 RNA in early mouse embryo development
Published in Developmental biology (01-06-1988)“…We have studied the accumulation and localization of U1 RNA during mouse embryo development by in situ hybridization with a U1 RNA probe and immunofluorescence…”
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Effect of delaying DNA replication on blastocyst formation in the mouse
Published in Differentiation (London) (01-01-1984)“…Differentiation in the early mouse embryo involves cellular responses to both spatial and temporal signals. The temporal signals that trigger blastocyst…”
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Syntenic Organization of the Mouse Distal Chromosome 7 Imprinting Cluster and the Beckwith-Wiedemann Syndrome Region in Chromosome 11p15.5
Published in Human molecular genetics (01-07-1998)“…In human and mouse, most imprinted genes are arranged in chromosomal clusters. Their linked organization suggests co-ordinated mechanisms controlling…”
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Relocalization of small ribonucleoprotein particles (snRNPs) during the first cell cycle of mouse embryo development is independent of RNA synthesis, DNA synthesis and cytokinesis
Published in Cell differentiation and development (01-07-1990)“…The process of localization of small nuclear ribonucleoprotein particles (snRNPs) during the first cell cycle of mouse embryo development was investigated…”
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Transgenic mice ubiquitously expressing human placental alkaline phosphatase (PLAP): an additional reporter gene for use in tandem with beta-galactosidase (lacZ)
Published in The International journal of developmental biology (01-01-1999)“…A fundamental keystone of developmental biology has been the growing use of reporter genes in model transgenic systems. Their use has greatly facilitated…”
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