Search Results - "Dean, Tyler"

Mitigating Disparate Elevation Differences between Adjacent Topobathymetric Data Models Using Binary Code by Cushing, William M, Tyler, Dean J

“…Integrating coastal topographic and bathymetric data for creating regional seamless topobathymetric digital elevation models of the land/water interface…”
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Click chemistry enables preclinical evaluation of targeted epigenetic therapies by Tyler, Dean S., Vappiani, Johanna, Cañeque, Tatiana, Lam, Enid Y. N., Ward, Aoife, Gilan, Omer, Chan, Yih-Chih, Hienzsch, Antje, Rutkowska, Anna, Werner, Thilo, Wagner, Anne J., Lugo, Dave, Gregory, Richard, Molina, Cesar Ramirez, Garton, Neil, Wellaway, Christopher R., Jackson, Susan, MacPherson, Laura, Figueiredo, Margarida, Stolzenburg, Sabine, Bell, Charles C., House, Colin, Dawson, Sarah-Jane, Hawkins, Edwin D., Drewes, Gerard, Prinjha, Rab K., Rodriguez, Raphaël, Grandi, Paola, Dawson, Mark A.

“…The success of new therapies hinges on our ability to understand their molecular and cellular mechanisms of action. We modified BET bromodomain inhibitors, an…”
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Measurements of no rotational and vibrational temperatures behind a normal shock in hypervelocity flow via absorption spectroscopy by Feltis, Samuel E., Zhang, Zhili, Dean, Tyler S., Bowersox, Rodney D. W., Siddiqui, Farhan, Gragston, Mark

“…Tunable Diode Laser Absorption Spectroscopy (TDLAS) measurements of nitric oxide (NO) using a Quantum Cascade Laser (QCL) in the vicinity of 5.26 μm were…”
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Parents’ receptiveness to oral health clinic-based vaccination by Dean, Tyler C., Gilliland, Aubrey E., Cameron, Jennifer E.

“…In the United States, utilization of the human papillomavirus (HPV) vaccine has lagged far below public health goals for achieving satisfactory…”
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A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques by Greyslak, Keenan T, Hetrick, Byron, Bergman, Bryan C, Dean, Tyler A, Wesolowski, Stephanie R, Gannon, Maureen, Schenk, Simon, Sullivan, Elinor L, Aagaard, Kjersti M, Kievit, Paul, Chicco, Adam J, Friedman, Jacob E, McCurdy, Carrie E

“…Maternal consumption of a Western-style diet (mWD) during pregnancy alters fatty acid metabolism and reduces insulin sensitivity in fetal skeletal muscle. The…”
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Maternal Obesity and Western-Style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates by Campodonico-Burnett, William, Hetrick, Byron, Wesolowski, Stephanie R, Schenk, Simon, Takahashi, Diana L, Dean, Tyler A, Sullivan, Elinor L, Kievit, Paul, Gannon, Maureen, Aagaard, Kjersti, Friedman, Jacob E, McCurdy, Carrie E

“…Infants born to mothers with obesity have a greater risk for childhood obesity and metabolic diseases; however, the underlying biological mechanisms remain…”
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Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring by Nash, Michael J., Dobrinskikh, Evgenia, Soderborg, Taylor K., Janssen, Rachel C., Takahashi, Diana L., Dean, Tyler A., Varlamov, Oleg, Hennebold, Jon D., Gannon, Maureen, Aagaard, Kjersti M., McCurdy, Carrie E., Kievit, Paul, Bergman, Bryan C., Jones, Kenneth L., Pietras, Eric M., Wesolowski, Stephanie R., Friedman, Jacob E.

“…Maternal overnutrition increases inflammatory and metabolic disease risk in postnatal offspring. This constitutes a major public health concern due to…”
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Maternal High‐Fat Diet Effects on Adaptations to Metabolic Challenges in Male and Female Juvenile Nonhuman Primates by True, Cadence, Dean, Tyler, Takahashi, Diana, Sullivan, Elinor, Kievit, Paul

“…Objective This study aimed to determine whether maternal high‐fat diet (HFD) consumption in nonhuman primates alters the ability of offspring to adapt…”
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Maternal Western-style diet in nonhuman primates leads to offspring islet adaptations including altered gene expression and insulin hypersecretion by Carroll, Darian T, Elsakr, Joseph M, Miller, Allie, Fuhr, Jennifer, Lindsley, Sarah Rene, Kirigiti, Melissa, Takahashi, Diana L, Dean, Tyler A, Wesolowski, Stephanie R, McCurdy, Carrie E, Friedman, Jacob E, Aagaard, Kjersti M, Kievit, Paul, Gannon, Maureen

“…Maternal overnutrition is associated with increased susceptibility to type 2 diabetes in the offspring. Rodent models have shown that maternal overnutrition…”
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Western-style diet consumption impairs maternal insulin sensitivity and glucose metabolism during pregnancy in a Japanese macaque model by Elsakr, Joseph M., Zhao, Sifang Kathy, Ricciardi, Valerie, Dean, Tyler A., Takahashi, Diana L., Sullivan, Elinor, Wesolowski, Stephanie R., McCurdy, Carrie E., Kievit, Paul, Friedman, Jacob E., Aagaard, Kjersti M.,  Edwards, Digna R. Velez, Gannon, Maureen

“…The prevalence of maternal obesity is increasing in the United States. Offspring born to women with obesity or poor glycemic control have greater odds of…”
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Maternal high‐fat diet and obesity impact palatable food intake and dopamine signaling in nonhuman primate offspring by Rivera, Heidi M., Kievit, Paul, Kirigiti, Melissa A., Bauman, Leigh Ann, Baquero, Karalee, Blundell, Peter, Dean, Tyler A., Valleau, Jeanette C., Takahashi, Diana L., Frazee, Tim, Douville, Luke, Majer, Jordan, Smith, M. Susan, Grove, Kevin L., Sullivan, Elinor L.

“…Objective To utilize a nonhuman primate model to examine the impact of maternal high‐fat diet (HFD) consumption and pre‐pregnancy obesity on offspring intake…”
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Topobathymetric Elevation Model Development using a New Methodology: Coastal National Elevation Database by Danielson, Jeffrey J, Poppenga, Sandra K, Brock, John C, Evans, Gayla A, Tyler, Dean J, Gesch, Dean B, Thatcher, Cindy A, Barras, John A

“…Danielson, J.J.; Poppenga, S.K.; Brock, J.C.; Evans, G.A.; Tyler, D.J.; Gesch, D.B.; Thatcher, C.A., and Barras, J.A., 2016. Topobathymetric elevation model…”
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Maternal and postnatal high-fat diet consumption programs energy balance and hypothalamic melanocortin signaling in nonhuman primate offspring by Sullivan, Elinor L, Rivera, Heidi M, True, Cadence A, Franco, Juliana G, Baquero, Karalee, Dean, Tyler A, Valleau, Jeanette C, Takahashi, Diana L, Frazee, Tim, Hanna, Genevieve, Kirigiti, Melissa A, Bauman, Leigh A, Grove, Kevin L, Kievit, Paul

“…Maternal high-fat-diet (HFD) consumption during pregnancy decreased fetal body weight and impacted development of hypothalamic melanocortin neural circuitry in…”
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The development and ecology of the Japanese macaque gut microbiome from weaning to early adolescence in association with diet by Prince, Amanda L., Pace, Ryan M., Dean, Tyler, Takahashi, Diana, Kievit, Paul, Friedman, Jacob E., Aagaard, Kjersti M.

“…Previously we have shown that the Japanese macaque gut microbiome differs not by obesity per se, but rather in association with high‐fat diet (HFD) feeding…”
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Analysis of beta-cell maturity and mitochondrial morphology in juvenile non-human primates exposed to maternal Western-style diet during development by Carroll, Darian T, Miller, Allie, Fuhr, Jennifer, Elsakr, Joseph M, Ricciardi, Valerie, Del Bene, Alexa N, Stephens, Stedman, Krystofiak, Evan, Lindsley, Sarah R, Kirigiti, Melissa, Takahashi, Diana L, Dean, Tyler A, Wesolowski, Stephanie R, McCurdy, Carrie E, Friedman, Jacob E, Aagaard, Kjersti M, Kievit, Paul, Gannon, Maureen

“…Using a non-human primate (NHP) model of maternal Western-style diet (mWSD) feeding during pregnancy and lactation, we previously reported altered offspring…”
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Maternal Diet, Metabolic State, and Inflammatory Response Exert Unique and Long-Lasting Influences on Offspring Behavior in Non-Human Primates by Thompson, Jacqueline R, Gustafsson, Hanna C, DeCapo, Madison, Takahashi, Diana L, Bagley, Jennifer L, Dean, Tyler A, Kievit, Paul, Fair, Damien A, Sullivan, Elinor L

“…Nutritional status influences brain health and gestational exposure to metabolic disorders (e.g. obesity and diabetes) increases the risk of neuropsychiatric…”
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Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates by Wesolowski, Stephanie R., Mulligan, Christopher M., Janssen, Rachel C., Baker, Peter R., Bergman, Bryan C., D'Alessandro, Angelo, Nemkov, Travis, Maclean, Kenneth N., Jiang, Hua, Dean, Tyler A., Takahashi, Diana L., Kievit, Paul, McCurdy, Carrie E., Aagaard, Kjersti M., Friedman, Jacob E.

“…Non-alcoholic fatty liver disease (NAFLD) risk begins in utero in offspring of obese mothers. A critical unmet need in this field is to understand the pathways…”
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Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition by Elsakr, Joseph M., Dunn, Jennifer C., Tennant, Katherine, Zhao, Sifang Kathy, Kroeten, Karly, Pasek, Raymond C., Takahashi, Diana L., Dean, Tyler A., Velez Edwards, Digna R., McCurdy, Carrie E., Aagaard, Kjersti M., Powers, Alvin C., Friedman, Jacob E., Kievit, Paul, Gannon, Maureen

“…In humans, offspring of women who are overweight or obese are more likely to develop metabolic disease later in life. Studies in lower animal species reveal…”
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Modulations in the offspring gut microbiome are refractory to postnatal synbiotic supplementation among juvenile primates by Pace, Ryan M, Prince, Amanda L, Ma, Jun, Belfort, Benjamin D W, Harvey, Alexia S, Hu, Min, Baquero, Karalee, Blundell, Peter, Takahashi, Diana, Dean, Tyler, Kievit, Paul, Sullivan, Elinor L, Friedman, Jacob E, Grove, Kevin, Aagaard, Kjersti M

“…We and others have previously shown that alterations in the mammalian gut microbiome are associated with diet, notably early life exposure to a maternal high…”
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Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques by McCurdy, Carrie E, Schenk, Simon, Hetrick, Byron, Houck, Julie, Drew, Brian G, Kaye, Spencer, Lashbrook, Melanie, Bergman, Bryan C, Takahashi, Diana L, Dean, Tyler A, Nemkov, Travis, Gertsman, Ilya, Hansen, Kirk C, Philp, Andrew, Hevener, Andrea L, Chicco, Adam J, Aagaard, Kjersti M, Grove, Kevin L, Friedman, Jacob E

“…Maternal obesity is proposed to alter the programming of metabolic systems in the offspring, increasing the risk for developing metabolic diseases; however,…”
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