Search Results - "Dean, Olivia M."

The chemistry and biological activities of N-acetylcysteine by Samuni, Yuval, Goldstein, Sara, Dean, Olivia M., Berk, Michael

“…N-acetylcysteine (NAC) has been in clinical practice for several decades. It has been used as a mucolytic agent and for the treatment of numerous disorders…”
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A randomised controlled trial of dietary improvement for adults with major depression (the 'SMILES' trial) by Jacka, Felice N, O'Neil, Adrienne, Opie, Rachelle, Itsiopoulos, Catherine, Cotton, Sue, Mohebbi, Mohammedreza, Castle, David, Dash, Sarah, Mihalopoulos, Cathrine, Chatterton, Mary Lou, Brazionis, Laima, Dean, Olivia M, Hodge, Allison M, Berk, Michael

“…The possible therapeutic impact of dietary changes on existing mental illness is largely unknown. Using a randomised controlled trial design, we aimed to…”
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The promise of N -acetylcysteine in neuropsychiatry by Berk, Michael, Malhi, Gin S, Gray, Laura J, Dean, Olivia M

“…N -Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of multiple neuropsychiatric disorders including glutamatergic…”
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Post-Operative Cognitive Dysfunction: An exploration of the inflammatory hypothesis and novel therapies by Skvarc, David R., Berk, Michael, Byrne, Linda K., Dean, Olivia M., Dodd, Seetal, Lewis, Matthew, Marriott, Andrew, Moore, Eileen M., Morris, Gerwyn, Page, Richard S., Gray, Laura

“…•Post-operative cognitive dysfunction (POCD) is an established risk of surgery.•The proposed feed-forward inflammatory process of POCD is well…”
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A model of the mitochondrial basis of bipolar disorder by Morris, Gerwyn, Walder, Ken, McGee, Sean L., Dean, Olivia M., Tye, Susannah J., Maes, Michael, Berk, Michael

“…•Bipolar disorder phenomenologically is a biphasic disorder of energy; increased in mania and decreased in depression.•There is evidence of increased…”
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The effect of N-acetylcysteine (NAC) on human cognition – A systematic review by Skvarc, David R., Dean, Olivia M., Byrne, Linda K., Gray, Laura, Lane, Stephen, Lewis, Matthew, Fernandes, Brisa S., Berk, Michael, Marriott, Andrew

“…•Oxidation and neuroinflammation modulate cognition through a variety of vectors.•NAC mitigates the cognitive effects of neuroinflammation in animals.•Evidence…”
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A Review of the Theoretical and Biological Understanding of the Nocebo and Placebo Phenomena by Dodd, Seetal, PhD, Dean, Olivia M., PhD, Vian, João, PhD, Berk, Michael, PhD

“…Abstract Purpose Placebos are commonly used in experimental and patient populations and are known to influence treatment outcomes. The mechanism of action of…”
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A randomised controlled trial of a mitochondrial therapeutic target for bipolar depression: mitochondrial agents, N-acetylcysteine, and placebo by Berk, Michael, Turner, Alyna, Malhi, Gin S, Ng, Chee H, Cotton, Susan M, Dodd, Seetal, Samuni, Yuval, Tanious, Michelle, McAulay, Claire, Dowling, Nathan, Sarris, Jerome, Owen, Lauren, Waterdrinker, Astrid, Smith, Deidre, Dean, Olivia M

“…A phasic dysregulation of mitochondrial bioenergetics may operate in bipolar disorder, increased in mania and decreased in depression. We aimed to examine…”
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Oxidative stress and post-stroke depression: possible therapeutic role of polyphenols? by Nabavi, Seyed Fazel, Dean, Olivia M, Turner, Alyna, Sureda, Antoni, Daglia, Maria, Nabavi, Seyed Mohammad

“…Post-stroke depression is a common neuropsychiatric affective disorder that may develop after a stroke event. In addition to abnormalities in the biogenic…”
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Novel Insights into Changes in Gene Expression within the Hypothalamus in Two Asthma Mouse Models: A Transcriptomic Lung-Brain Axis Study by Bastawy, Eslam M, Eraslan, Izel M, Voglsanger, Lara, Suphioglu, Cenk, Walker, Adam J, Dean, Olivia M, Read, Justin L, Ziemann, Mark, Smith, Craig M

“…Patients with asthma experience elevated rates of mental illness. However, the molecular links underlying such lung-brain crosstalk remain ambiguous…”
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Minocycline as Treatment for Psychiatric and Neurological Conditions: A Systematic Review and Meta-Analysis by Panizzutti, Bruna, Skvarc, David, Lin, Sylvia, Croce, Sarah, Meehan, Alcy, Bortolasci, Chiara Cristina, Marx, Wolfgang, Walker, Adam J, Hasebe, Kyoko, Kavanagh, Bianca E, Morris, Margaret J, Mohebbi, Mohammadreza, Turner, Alyna, Gray, Laura, Berk, Lesley, Walder, Ken, Berk, Michael, Dean, Olivia M

“…Minocycline has anti-inflammatory, antioxidant, and anti-apoptotic properties that explain the renewed interest in its use as an adjunctive treatment for…”
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Youth Depression Alleviation with Anti-inflammatory Agents (YoDA-A): a randomised clinical trial of rosuvastatin and aspirin by Berk, Michael, Mohebbi, Mohammadreza, Dean, Olivia M, Cotton, Sue M, Chanen, Andrew M, Dodd, Seetal, Ratheesh, Aswin, Amminger, G Paul, Phelan, Mark, Weller, Amber, Mackinnon, Andrew, Giorlando, Francesco, Baird, Shelley, Incerti, Lisa, Brodie, Rachel E, Ferguson, Natalie O, Rice, Simon, Schäfer, Miriam R, Mullen, Edward, Hetrick, Sarah, Kerr, Melissa, Harrigan, Susy M, Quinn, Amelia L, Mazza, Catherine, McGorry, Patrick, Davey, Christopher G

“…Inflammation contributes to the pathophysiology of major depressive disorder (MDD), and anti-inflammatory strategies might therefore have therapeutic…”
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Effects of Psychotropic Drugs on Ribosomal Genes and Protein Synthesis by Liu, Zoe S. J., Truong, Trang T. T., Bortolasci, Chiara C., Spolding, Briana, Panizzutti, Bruna, Swinton, Courtney, Kim, Jee Hyun, Kidnapillai, Srisaiyini, Richardson, Mark F., Gray, Laura, Dean, Olivia M., McGee, Sean L., Berk, Michael, Walder, Ken

“…Altered protein synthesis has been implicated in the pathophysiology of several neuropsychiatric disorders, particularly schizophrenia. Ribosomes are the…”
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Transcriptional Modulation of the Hippo Signaling Pathway by Drugs Used to Treat Bipolar Disorder and Schizophrenia by Panizzutti, Bruna, Bortolasci, Chiara C, Spolding, Briana, Kidnapillai, Srisaiyini, Connor, Timothy, Richardson, Mark F, Truong, Trang T T, Liu, Zoe S J, Morris, Gerwyn, Gray, Laura, Hyun Kim, Jee, Dean, Olivia M, Berk, Michael, Walder, Ken

“…Recent reports suggest a link between positive regulation of the Hippo pathway with bipolar disorder (BD), and the Hippo pathway is known to interact with…”
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Integrative Analyses of Transcriptomes to Explore Common Molecular Effects of Antipsychotic Drugs by Truong, Trang T. T., Bortolasci, Chiara C., Kidnapillai, Srisaiyini, Spolding, Briana, Panizzutti, Bruna, Liu, Zoe S. J., Kim, Jee Hyun, Dean, Olivia M., Richardson, Mark F., Berk, Michael, Walder, Ken

“…There is little understanding of the underlying molecular mechanism(s) involved in the clinical efficacy of antipsychotics for schizophrenia. This study…”
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Personality disorder increases risk of low quality of life among women with mental state disorders by Kavanagh, Bianca E., Stuart, Amanda L., Berk, Michael, Turner, Alyna, Dean, Olivia M., Pasco, Julie A., Jackson, Henry J., Koivumaa-Honkanen, Heli, Chanen, Andrew M., Williams, Lana J.

“…Limited data are available examining the relationship between mental state disorders (mood, anxiety, substance use, eating disorders), their co-occurrence with…”
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Transcriptional Effects of Psychoactive Drugs on Genes Involved in Neurogenesis by Bortolasci, Chiara C, Spolding, Briana, Kidnapillai, Srisaiyini, Connor, Timothy, Truong, Trang T T, Liu, Zoe S J, Panizzutti, Bruna, Richardson, Mark F, Gray, Laura, Berk, Michael, Dean, Olivia M, Walder, Ken

“…Although neurogenesis is affected in several psychiatric diseases, the effects and mechanisms of action of psychoactive drugs on neurogenesis remain unknown…”
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Influence of childhood trauma on the treatment outcomes of pharmacological and/or psychological interventions for adolescents and adults with bipolar disorder: protocol for a systematic review and meta-analysis by Wrobel, Anna, Russell, Samantha E, Dean, Olivia M, Cotton, Sue, Berk, Michael, Turner, Alyna

“…IntroductionDespite available pharmacological and psychological treatments, remission rates for bipolar disorder remain relatively low. Current research…”
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N-acetylcysteine for cessation of tobacco smoking: rationale and study protocol for a randomised controlled trial by Arancini, Lauren, Bortolasci, Chiara C, Dodd, Seetal, Dean, Olivia M, Berk, Michael

“…Tobacco smoking is a highly prevalent, addictive behaviour and a key public health priority. However available cessation therapies have low quit and high…”
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Co-Expression Networks Unveiled Long Non-Coding RNAs as Molecular Targets of Drugs Used to Treat Bipolar Disorder by Truong, Trang Tt, Bortolasci, Chiara C, Spolding, Briana, Panizzutti, Bruna, Liu, Zoe Sj, Kidnapillai, Srisaiyini, Richardson, Mark, Gray, Laura, Smith, Craig M, Dean, Olivia M, Kim, Jee Hyun, Berk, Michael, Walder, Ken

“…Long non-coding RNAs (lncRNAs) may play a role in psychiatric diseases including bipolar disorder (BD). We investigated mRNA-lncRNA co-expression patterns in…”
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