Search Results - "Dean, O.M."
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Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors
Published in Neuroscience and biobehavioral reviews (01-01-2011)“…▶ Bipolar disorder is associated with an active process of neuroprogression. ▶ Oxidative, inflammatory and neurotrophic factors play a role in the process. ▶…”
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N -acetyl cysteine add-on treatment for bipolar II disorder: a subgroup analysis of a randomized placebo-controlled trial
Published in Journal of affective disorders (01-03-2011)“…Abstract Background The evidence base for the pharmacological treatment of bipolar II disorder is limited. In bipolar disorder, there is evidence for…”
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C-reactive protein is increased in schizophrenia but is not altered by antipsychotics: meta-analysis and implications
Published in Molecular psychiatry (01-04-2016)“…The inflammatory hypothesis of schizophrenia (SZ) posits that inflammatory processes and neural–immune interactions are involved in its pathogenesis, and may…”
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Patient centric measures for a patient centric era: Agreement and convergent between ratings on The Patient Global Impression of Improvement (PGI-I) scale and the Clinical Global Impressions – Improvement (CGI-S) scale in bipolar and major depressive disorder
Published in European psychiatry (01-09-2018)“…Concordant with an increased emphasis on consumer engagement, the Patient Global Impression Scale of Improvement (PGI-I) is commonly used as an outcome measure…”
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Equal remission rates and reduced length of hospital stay with twice-daily repetitive transcranial magnetic stimulation (rTMS) for major depression – A large naturalistic retrospective cohort association study
Published in Progress in neuro-psychopharmacology & biological psychiatry (20-12-2023)“…Repetitive transcranial magnetic stimulation (rTMS) is a level 1a evidence-based treatment for major depression, but high cost of care and limited…”
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Evaluation of high dose N- Acetylcysteine on airway inflammation and quality of life outcomes in adults with bronchiectasis: A randomised placebo-controlled pilot study
Published in Pulmonary pharmacology & therapeutics (01-03-2024)“…High dose N acetylcysteine (NAC), a mucolytic, anti-inflammatory and antioxidant agent has been shown to significantly reduce exacerbations, and improve…”
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Systemic illness moderates the impact of N-acetyl cysteine in bipolar disorder
Published in Progress in neuro-psychopharmacology & biological psychiatry (27-04-2012)“…Bipolar disorder (BD) is intricately associated with chronic clinical conditions. Medical comorbidity is not only more prevalent in mood disorders, but is…”
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