Search Results - "Dean, D.K."

Non thiazolidinedione antihyperglycaemic agents. 1: α-Heteroatom substituted β-phenylpropanoic acids by Buckle, D.R., Cantello, B.C.C., Cawthorne, M.A., Coyle, P.J., Dean, D.K., Faller, A., Haigh, D., Hindley, R.M., Jefcott, L.J., Lister, C.A., Pinto, I.L., Rami, H.K., Smith, D.G., Smith, S.A.

“…The 5-benzylthiazolidine-2,4-dione moiety of insulin sensitising antidiabetic agents can be replaced by a range of α-heteroatom functionalised…”
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Non thiazolidinedione antihyperglycaemic agents. 2: α-Carbon substituted β-phenylpropanoic acids1 by Buckle, D.R., Cantello, B.C.C., Cawthorne, M.A., Coyle, P.J., Dean, D.K., Faller, A., Haigh, D., Hindley, R.M., Jefcott, L.J., Lister, C.A., Pinto, I.L., Rami, H.K., Smith, D.G., Smith, S.A.

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Non thiazolidinedione antihyperglycaemic agents. 2: α-Carbon substituted β-phenylpropanoic acids 1 by Buckle, D.R., Cantello, B.C.C., Cawthorne, M.A., Coyle, P.J., Dean, D.K., Faller, A., Haigh, D., Hindley, R.M., Jefcott, L.J., Lister, C.A., Pinto, I.L., Rami, H.K., Smith, D.G., Smith, S.A.

“…The thiazolidine-2,4-dione ring of insulin sensitising antidiabetic agents can be replaced by α-acyl-, α-alkyl- and α-(aralkyl)-carboxylic acids. Inclusion of…”
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A simplified template approach towards the synthesis of a potent beta-3 adrenoceptor agonist at the human receptor by Beeley, L.J., Berge, J.M., Chapman, H., Dean, D.K., Kelly, J., Lowden, K., Kotecha, N.R., Morgan, H.K.A., Rami, H.K., Thompson, M., Vong, A.K.K., Ward, R.W.

“…A simplified template approach was used to delineate the structural requirements for high potency and intrinsic activity of aryloxypropanolamines as agonists…”
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