Search Results - "Dealy, Shannon"
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Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II
Published in Proceedings of the National Academy of Sciences - PNAS (08-05-2018)“…Initiation and promoter-proximal pausing are key regulatory steps of RNA Polymerase II (Pol II) transcription. To study the in vivo dynamics of endogenous Pol…”
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Journal Article -
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Transcription-coupled DNA–protein crosslink repair by CSB and CRL4CSA-mediated degradation
Published in Nature cell biology (01-05-2024)“…DNA–protein crosslinks (DPCs) arise from enzymatic intermediates, metabolism or chemicals like chemotherapeutics. DPCs are highly cytotoxic as they impede…”
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Journal Article -
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Transcription-coupled DNA-protein crosslink repair by CSB and CRL4 CSA -mediated degradation
Published in Nature cell biology (10-04-2024)“…DNA-protein crosslinks (DPCs) arise from enzymatic intermediates, metabolism or chemicals like chemotherapeutics. DPCs are highly cytotoxic as they impede…”
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Journal Article