Search Results - "Deal, Aaron W"
-
1
Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model
Published in Scientific reports (22-01-2021)“…Chronic kidney disease (CKD), which can ultimately progress to kidney failure, is influenced by genetics and the environment. Genes identified in human genome…”
Get full text
Journal Article -
2
High-fat diet negatively impacts both metabolic and behavioral health in outbred heterogeneous stock rats
Published in Physiological genomics (01-09-2020)“…Obesity is influenced by genetics and diet and has wide ranging comorbidities, including anxiety and depressive disorders. Outbred heterogeneous stock (HS)…”
Get full text
Journal Article -
3
Identification of RTS,S/AS01 vaccine-induced humoral biomarkers predictive of protection against controlled human malaria infection
Published in JCI insight (08-10-2024)“…BACKGROUNDThe mechanism(s) responsible for the efficacy of WHO-recommended malaria vaccine RTS,S/AS01 are not completely understood. We previously identified…”
Get full text
Journal Article -
4
Computational analysis of antibody dynamics identifies recent HIV-1 infection
Published in JCI insight (21-12-2017)“…Accurate HIV-1 incidence estimation is critical to the success of HIV-1 prevention strategies. Current assays are limited by high false recent rates (FRRs) in…”
Get full text
Journal Article -
5
High Fat Diet Negatively Impacts both Metabolic and Emotional Health in an Outbred Rat Model
Published in The FASEB journal (01-04-2019)“…Obesity is a growing epidemic associated with a range of comorbidities, including depression and anxiety. Increasing evidence in humans suggests shared…”
Get full text
Journal Article -
6
Investigation into Gene-By-Diet Interactions and the Role of the Gut Microbiome in Diet-Induced Changes on Metabolic and Behavioral Traits in Heterogeneous Stock Rats
Published 01-01-2022“…Obesity and mental health show a bidirectional relationship and each is influenced by genetic background, diet, and the gut microbiome. However, factors…”
Get full text
Dissertation