Search Results - "Deak, Andras T."
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Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo
Published in Nature communications (10-11-2017)“…Changes in intra- and extracellular potassium ion (K + ) concentrations control many important cellular processes and related biological functions. However,…”
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Molecularly Distinct Routes of Mitochondrial Ca2+ Uptake Are Activated Depending on the Activity of the Sarco/Endoplasmic Reticulum Ca2+ ATPase (SERCA)
Published in The Journal of biological chemistry (24-05-2013)“…The transfer of Ca2+ across the inner mitochondrial membrane is an important physiological process linked to the regulation of metabolism, signal transduction,…”
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Hypomagnesemia Is a Risk Factor for Infections after Kidney Transplantation: A Retrospective Cohort Analysis
Published in Nutrients (14-04-2021)“…Magnesium (Mg ) deficiency is a common finding in the early phase after kidney transplantation (KT) and has been linked to immune dysfunction and infections…”
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Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum
Published in Sensors (Basel, Switzerland) (04-06-2015)“…Cameleons are sophisticated genetically encoded fluorescent probes that allow quantifying cellular Ca2+ signals. The probes are based on Förster resonance…”
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Spatiotemporal Correlations between Cytosolic and Mitochondrial Ca2+ Signals Using a Novel Red-Shifted Mitochondrial Targeted Cameleon
Published in PloS one (21-09-2012)“…The transfer of Ca2+ from the cytosol into the lumen of mitochondria is a crucial process that impacts cell signaling in multiple ways. Cytosolic Ca2+…”
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Spatiotemporal correlations between cytosolic and mitochondrial Ca(2+) signals using a novel red-shifted mitochondrial targeted cameleon
Published in PloS one (2012)“…The transfer of Ca(2+) from the cytosol into the lumen of mitochondria is a crucial process that impacts cell signaling in multiple ways. Cytosolic Ca(2+)…”
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IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake
Published in Journal of cell science (01-07-2014)“…Mitochondria contribute to cell signaling by controlling store-operated Ca(2+) entry (SOCE). SOCE is activated by Ca(2+) release from the endoplasmic reticulum…”
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Impact of cardiovascular risk stratification strategies in kidney transplantation over time
Published in Nephrology, dialysis, transplantation (01-10-2020)“…Abstract Background Kidney transplant recipients exhibit a dramatically increased cardiovascular (CV) risk. In 2007, Austrian centres implemented a consensus…”
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Salivary potassium measured by genetically encoded potassium ion indicators as a surrogate for plasma potassium levels in hemodialysis patients—a proof-of-concept study
Published in Nephrology, dialysis, transplantation (28-02-2023)“…ABSTRACT Background Hyperkalemia is a common complication in cardiorenal patients treated with agents interfering with renal potassium (K+) excretion. It…”
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Anemia management in cancer patients with chronic kidney disease
Published in European journal of internal medicine (01-12-2016)“…Abstract Anemia is a common complication of cancer and chronic kidney disease (CKD) associated with decreased physical performance as well as poor prognosis…”
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N‐arachidonoyl glycine suppresses Na+/Ca2+ exchanger‐mediated Ca2+ entry into endothelial cells and activates BKCa channels independently of GPCRs
Published in British journal of pharmacology (01-06-2013)“…Background and Purpose N‐arachidonoyl glycine (NAGly) is a lipoamino acid with vasorelaxant properties. We aimed to explore the mechanisms of NAGly's action on…”
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The endocannabinoid N-arachidonoyl glycine (NAGly) inhibits store-operated Ca2+ entry by preventing STIM1-Orai1 interaction
Published in Journal of cell science (15-02-2013)“…The endocannabiniod anandamide (AEA) and its derivate N-arachidonoyl glycine (NAGly) have a broad spectrum of physiological effects, which are induced by both…”
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High-Resolution Imaging of STIM/Orai Subcellular Localization Using Array Confocal Laser Scanning Microscopy
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2018)“…The expression of chimeras that consist of a fluorescent protein (FP) conjugated with a protein of interest provides the ability to visualize, track, and…”
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Impact of Timely Public Health Measures on Kidney Transplantation in Austria during the SARS-CoV-2 Outbreak—A Nationwide Analysis
Published in Journal of clinical medicine (28-10-2020)“…SARS-CoV-2 led to considerable morbidity/mortality worldwide and tremendously impacted on daily life. Strict lockdown measures were implemented early to…”
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Assessment of mitochondrial Ca²⁺ uptake
Published in Methods in molecular biology (Clifton, N.J.) (2015)“…Mitochondrial Ca(2+) uptake regulates mitochondrial function and contributes to cell signaling. Accordingly, quantifying mitochondrial Ca(2+) signals and…”
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The endocannabinoid N-arachidonoyl glycine (NAGly) inhibits store-operated Ca2+ entry by abrogating STIM1/Orai1 interaction
Published in Journal of cell science (13-12-2012)“…The endocannabiniod anandamide (AEA) and its derivate N-arachidonoyl glycine (NAGly) have a broad spectrum of physiological effects, which are induced by both…”
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N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs
Published in British journal of pharmacology (01-06-2013)“…N-Arachidonoyl glycine (NAGly) is a lipoamino acid with vasorelaxant properties. We aimed to explore the mechanisms of NAGly's action on unstimulated and…”
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