Search Results - "DeWard, Aaron D."
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Cellular Heterogeneity in the Mouse Esophagus Implicates the Presence of a Nonquiescent Epithelial Stem Cell Population
Published in Cell reports (Cambridge) (23-10-2014)“…Because the esophageal epithelium lacks a defined stem cell niche, it is unclear whether all basal epithelial cells in the adult esophagus are functionally…”
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Journal Article -
2
Ubiquitin-mediated Degradation of the Formin mDia2 upon Completion of Cell Division
Published in The Journal of biological chemistry (24-07-2009)“…Formins assemble non-branched actin filaments and modulate microtubule dynamics during cell migration and cell division. At the end of mitosis formins…”
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Journal Article -
3
RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking
Published in Experimental cell research (01-02-2007)“…Rho GTPases and the dynamic assembly and disassembly of actin filaments have been shown to have critical roles in both the internalization and trafficking of…”
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4
Loss of RhoB expression enhances the myelodysplastic phenotype of mammalian diaphanous-related Formin mDia1 knockout mice
Published in PloS one (21-09-2009)“…Myelodysplastic syndrome (MDS) is characterized by ineffective hematopoiesis and hyperplastic bone marrow. Complete loss or interstitial deletions of the long…”
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Journal Article -
5
Independent Blinded Validation of a Tissue Systems Pathology Test to Predict Progression in Patients With Barrett's Esophagus
Published in The American journal of gastroenterology (01-06-2020)“…A risk prediction test was previously validated to predict progression to high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) in patients with…”
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Journal Article -
6
Ectopic transplantation sites for cell-based therapy
Published in Current opinion in organ transplantation (01-04-2014)“…This review outlines the concept of cell-based therapy to restore tissue function, and addresses four key points to consider in cell transplantation: source,…”
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Journal Article -
7
The role of formins in human disease
Published in Biochimica et biophysica acta (01-02-2010)“…Formins are a conserved family of proteins that play key roles in cytoskeletal remodeling. They nucleate and processively elongate non-branched actin filaments…”
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Journal Article -
8
Signatures of field cancerization: a step towards earlier detection of esophageal adenocarcinoma
Published in Translational cancer research (01-08-2017)Get full text
Journal Article -
9
Potential Barriers to Human Hepatocyte Transplantation in MUP–uPARag2γC Mice
Published in Cell transplantation (01-12-2014)“…Primary human fetal and adult hepatocytes have been considered feasible donor cell sources for cell transplantation. We compared the engraftment efficiencies…”
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Journal Article -
10
Microtubule Stabilization: Formins Assert Their Independence
Published in Current biology (22-07-2008)“…Mammalian Diaphanous-related (mDia) formins are well known for their actin nucleation and filament elongation activities. They have since emerged as…”
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Journal Article -
11
Potential barriers to human hepatocyte transplantation in MUP-uPAtg(⁺/⁺)Rag2⁻/⁻γC⁻/⁻ mice
Published in Cell transplantation (2014)“…Primary human fetal and adult hepatocytes have been considered feasible donor cell sources for cell transplantation. We compared the engraftment efficiencies…”
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Journal Article -
12
Independent Blinded Validation of a Tissue Systems Pathology Test to Predict Progression in Barrett’s Esophagus Patients
Published in The American journal of gastroenterology (01-06-2020)Get full text
Journal Article -
13
1068 – Independent Validation of a Tissue Systems Pathology Test to Predict Progression in Barrett's Esophagus Patients
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2019)Get full text
Journal Article -
14
Cellular heterogeneity in the mouse esophagus implicates the presence of a non-quiescent epithelial stem cell population
Published in Cell reports (Cambridge) (16-10-2014)“…Because the esophageal epithelium lacks a defined stem cell niche, it is unclear whether all basal epithelial cells in the adult esophagus are functionally…”
Get full text
Journal Article -
15
Molecular control of diaphanous-related formins in cell biology and disease
Published 01-01-2009“…Formins are a conserved family of proteins that govern cytoskeletal remodeling in the cell. Common among all formins is the Formin Homology-2 domain, which is…”
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Dissertation -
16
Molecular control of diaphanous-related formins in cell biology and disease
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Dissertation