Search Results - "DeWan, Andrew Thomas"
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A new method for exploring gene-gene and gene-environment interactions in GWAS with tree ensemble methods and SHAP values
Published in BMC bioinformatics (04-05-2021)“…The identification of gene-gene and gene-environment interactions in genome-wide association studies is challenging due to the unknown nature of the…”
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Inferring feature importance with uncertainties with application to large genotype data
Published in PLoS computational biology (01-03-2023)“…Estimating feature importance, which is the contribution of a prediction or several predictions due to a feature, is an essential aspect of explaining…”
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Preimplantation genetic testing for aneuploidy: challenges in clinical practice
Published in Human genomics (20-12-2022)“…Preimplantation genetic testing for aneuploidy (PGT-A) has been used widely during in vitro fertilization procedures in assisted reproductive centers…”
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Genome-Wide Linkage Analysis of the Risk of Contracting a Bloodstream Infection in 47 Pedigrees Followed for 23 Years Assembled From a Population-Based Cohort (the HUNT Study)
Published in Critical care medicine (01-11-2020)“…OBJECTIVES:Bloodstream infection is an important cause of death worldwide. The main objective of this study was to identify genetic loci linked to risk of…”
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Saddlepoint approximations to score test statistics in logistic regression for analyzing genome‐wide association studies
Published in Statistics in medicine (20-07-2023)“…We investigate saddlepoint approximations of tail probabilities of the score test statistic in logistic regression for genome‐wide association studies. The…”
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The Role of FER rs4957796 in the Risk of Developing and Dying from a Bloodstream Infection: A 23-Year Follow-up of the Population-based Nord-Trøndelag Health Study
Published in Clinical infectious diseases (15-07-2021)“…Abstract Background Bloodstream infection and sepsis are major causes of health loss worldwide, and it is important to identify patients at risk of developing…”
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Mendelian randomization study of birthweight, gestational age, and risk of childhood acute lymphoblastic leukemia
Published in American journal of obstetrics & gynecology MFM (01-09-2023)Get full text
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Rates of Neuropsychiatric Disorders and Gestational Age at Birth in a Danish Population
Published in Obstetrical & gynecological survey (01-12-2021)“…(Abstracted from JAMA Network Open 2021;4:e2114913) Gestational age (GA) is associated with brain growth and development. When the duration of gestation is not…”
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Rates of Neuropsychiatric Disorders and Gestational Age at Birth in a Danish Population
Published in JAMA network open (29-06-2021)“…Nonoptimal gestational durations could be associated with neurodevelopmental disabilities, yet evidence regarding finer classification of gestational age and…”
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Saddlepoint approximations in binary genome-wide association studies
Published 08-10-2021“…We investigate saddlepoint approximations applied to the score test statistic in genome-wide association studies with binary phenotypes. The inaccuracy in the…”
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Inferring feature importance with uncertainties in high-dimensional data
Published 02-09-2021“…Estimating feature importance is a significant aspect of explaining data-based models. Besides explaining the model itself, an equally relevant question is…”
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