Search Results - "DeWall, Stephen L"

A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus by McKie, Elizabeth A, Reid, Juliet L, Mistry, Prafull C, DeWall, Stephen L, Abberley, Lee, Ambery, Philip D, Gil-Extremera, Blas

“…Evidence suggests that chronic subclinical inflammation plays an important role in the pathogenesis of type 2 diabetes (T2DM). Circulating levels of…”
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Characterization of the robust humoral immune response to GSK2618960, a humanized anti-IL-7 receptor monoclonal antibody, observed in healthy subjects in a Phase 1 study by Liao, Karen, Chen, Keguan, Brett, Sara, Gehman, Andrew, Schwartz, Ann M, Gunn, George R, DeWall, Stephen L

“…Interleukin-7 (IL-7) signaling modulates T cell activity and is implicated in numerous autoimmune diseases. An anti-IL-7 receptor monoclonal antibody…”
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Immunogenicity Risk Assessment for PEGylated Therapeutics by Mora, Johanna R., White, Joleen T., DeWall, Stephen L.

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Immunogenicity Risk Assessment for PEGylated Therapeutics by Mora, Johanna R., White, Joleen T., DeWall, Stephen L.

“…The objective of this manuscript is to provide the reader with two examples on how to present an immunogenicity risk assessment for a PEGylated therapeutic as…”
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False-positive immunogenicity responses are caused by CD20+ B cell membrane fragments in an anti-ofatumumab antibody bridging assay by Chen, Keguan, Page, Jerry G., Schwartz, Ann M., Lee, Thomas N., DeWall, Stephen L., Sikkema, Daniel J., Wang, Catherine

“…An electrochemiluminescent (ECL) bridging assay to detect anti-ofatumumab antibodies (ADA) in human serum samples was developed and validated. Using this assay…”
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A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus: e0150018 by McKie, Elizabeth A, Reid, Juliet L, Mistry, Prafull C, DeWall, Stephen L, Abberley, Lee, Ambery, Philip D, Gil-Extremera, Blas

“…Objective Evidence suggests that chronic subclinical inflammation plays an important role in the pathogenesis of type 2 diabetes (T2DM). Circulating levels of…”
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Steroidal Aza-Lariat Ethers: Syntheses and Aggregation Behavior by Nakano, Akio, Hernandez, Jeanette C., Dewall, Stephen L., Wang, Keshi, Bergerc, Daniel R., Gokel, George W.

“…Ten steroid-substituted lariat ether compounds have been prepared including one- and two-armed derivatives of aza-15-crown-5 and aza- and diaza-18-crown-6…”
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