Search Results - "DeVico, Anthony"

Performance of nucleocapsid and spike-based SARS-CoV-2 serologic assays by Rikhtegaran Tehrani, Zahra, Saadat, Saman, Saleh, Ebtehal, Ouyang, Xin, Constantine, Niel, DeVico, Anthony L, Harris, Anthony D, Lewis, George K, Kottilil, Shyam, Sajadi, Mohammad M

“…There is an urgent need for an accurate antibody test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have developed 3 ELISA methods,…”
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Antibody persistence and T-cell balance: Two key factors confronting HIV vaccine development by Lewis, George K., DeVico, Anthony L., Gallo, Robert C.

“…The quest for a prophylactic AIDS vaccine is ongoing, but it is now clear that the successful vaccine must elicit protective antibody responses. Accordingly,…”
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Antigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cells by Mengistu, Meron, Ray, Krishanu, Lewis, George K, DeVico, Anthony L

“…The HIV-1 envelope glycoprotein, gp120, undergoes multiple molecular interactions and structural rearrangements during the course of host cell attachment and…”
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Survivors Remorse: antibody‐mediated protection against HIV‐1 by Lewis, George K., Pazgier, Marzena, DeVico, Anthony L.

“…Summary It is clear that antibodies can play a pivotal role in preventing the transmission of HIV‐1 and large efforts to identify an effective antibody‐based…”
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Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fcγ Receptor Binding by Orlandi, Chiara, Deredge, Daniel, Ray, Krishanu, Gohain, Neelakshi, Tolbert, William, DeVico, Anthony L., Wintrode, Patrick, Pazgier, Marzena, Lewis, George K.

“…Antibody structure couples adaptive and innate immunity via Fab (antigen binding) and Fc (effector) domains that are connected by unique hinge regions. Because…”
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Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses by Sajadi, Mohammad Mohseni, Dashti, Amir, Rikhtegaran Tehrani, Zahra, Tolbert, William D., Seaman, Michael S., Ouyang, Xin, Gohain, Neelakshi, Pazgier, Marzena, Kim, Dongkyoon, Cavet, Guy, Yared, Jean, Redfield, Robert R., Lewis, George K., DeVico, Anthony L.

“…Anti-HIV-1 envelope broadly neutralizing monoclonal antibodies (bNAbs) isolated from memory B cells may not fully represent HIV-1-neutralizing profiles…”
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Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region by Tolbert, William D., Gohain, Neelakshi, Veillette, Maxime, Chapleau, Jean-Philippe, Orlandi, Chiara, Visciano, Maria L., Ebadi, Maryam, DeVico, Anthony L., Fouts, Timothy R., Finzi, Andrés, Lewis, George K., Pazgier, Marzena

“…Evidence supports a role of antibody-dependent cellular cytotoxicity (ADCC) toward transitional epitopes in the first and second constant (C1-C2) regions of…”
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Identifying CCR5 coreceptor populations permissive for HIV-1 entry and productive infection: implications for in vivo studies by Weichseldorfer, Matthew, Tagaya, Yutaka, Reitz, Marvin, DeVico, Anthony L, Latinovic, Olga S

“…The chemokine receptor CCR5 is the major coreceptor for HIV-1 cell entry. We previously observed that not all CCR5 mAbs reduce HIV-1 infection, suggesting that…”
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Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding by Guan, Yongjun, Pazgier, Marzena, Sajadi, Mohammad M, Kamin-Lewis, Roberta, Al-Darmarki, Salma, Flinko, Robin, Lovo, Elena, Wu, Xueji, Robinson, James E, Seaman, Michael S, Fouts, Timothy R, Gallo, Robert C, DeVico, Anthony L, Lewis, George K

“…The HIV-1 envelope glycoprotein (Env) undergoes conformational transitions consequent to CD4 binding and coreceptor engagement during viral entry. The physical…”
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Broadly Neutralizing Antibodies against HIV: Back to Blood by Dashti, Amir, DeVico, Anthony L., Lewis, George K., Sajadi, Mohammad M.

“…After years of continuous exposure to HIV envelope antigens, a minority of HIV-infected individuals develop a cognate polyclonal humoral response comprising…”
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Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1 by Gohain, Neelakshi, Tolbert, William D, Acharya, Priyamvada, Yu, Lei, Liu, Tongyun, Zhao, Pingsen, Orlandi, Chiara, Visciano, Maria L, Kamin-Lewis, Roberta, Sajadi, Mohammad M, Martin, Loïc, Robinson, James E, Kwong, Peter D, DeVico, Anthony L, Ray, Krishanu, Lewis, George K, Pazgier, Marzena

“…Accumulating evidence indicates a role for Fc receptor (FcR)-mediated effector functions of antibodies, including antibody-dependent cell-mediated cytotoxicity…”
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Discordant Antigenic Properties of Soluble and Virion SARS-CoV-2 Spike Proteins by Kumar, Sameer, Dasgupta, Souradip, Sajadi, Mohammad M, Snyder, Greg A, DeVico, Anthony L, Ray, Krishanu

“…Efforts to develop vaccine and immunotherapeutic countermeasures against the COVID-19 pandemic focus on targeting the trimeric spike (S) proteins of…”
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Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1 by Lewis, George K, Finzi, Andrés, DeVico, Anthony L, Pazgier, Marzena

“…The mechanism of antibody-mediated protection is a major focus of HIV-1 vaccine development and a significant issue in the control of viremia. Virus…”
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Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection by Fouts, Timothy R., Bagley, Kenneth, Prado, Ilia J., Bobb, Kathryn L., Schwartz, Jennifer A., Xu, Rong, Zagursky, Robert J., Egan, Michael A., Eldridge, John H., LaBranche, Celia C., Montefiori, David C., Le Buanec, Hélène, Zagury, Daniel, Pal, Ranajit, Pavlakis, George N., Felber, Barbara K., Franchini, Genoveffa, Gordon, Shari, Vaccari, Monica, Lewis, George K., DeVico, Anthony L., Gallo, Robert C.

“…Significance Our candidate HIV vaccine, a single-chain gp120-CD4 chimera, elicits protection against acquisition of simian-human immunodeficiency virus…”
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Antigenic Properties of the HIV Envelope on Virions in Solution by Ray, Krishanu, Mengistu, Meron, Yu, Lei, Lewis, George K, Lakowicz, Joseph R, DeVico, Anthony L

“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Retraction for Khattar et al., "Newcastle Disease Virus Expressing Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Induces Strong Mucosal and Serum Antibody Responses in Guinea Pigs" by Khattar, Sunil K, Samal, Sweety, DeVico, Anthony L, Collins, Peter L, Samal, Siba K

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Evidence of variable human Fcγ receptor-Fc affinities across differentially-complexed IgG by Crowley, Andrew R, Mehlenbacher, Matthew R, Sajadi, Mohammad M, DeVico, Anthony L, Lewis, George K, Ackerman, Margaret E

“…Antibody-mediated effector functions are widely considered to unfold according to an associative model of IgG-Fcγ receptor (FcγR) interactions. The associative…”
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Conserved signatures indicate HIV-1 transmission is under strong selection and thus is not a "stochastic" process by Gonzalez, Mileidy, DeVico, Anthony L, Spouge, John L

“…Recently, Oberle et al. published a paper in Retrovirology evaluating the question of whether selection plays a role in HIV transmission. The Oberle study…”
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Rational Engraftment of Quaternary-Interactive Acidic Loops for Anti-HIV-1 Antibody Improvement by Liu, Qingbo, Zhang, Peng, Miao, Huiyi, Lin, Yin, Kwon, Young Do, Kwong, Peter D, Rikhtegaran-Tehrani, Zahra, Seaman, Michael S, DeVico, Anthony L, Sajadi, Mohammad M, Lusso, Paolo

“…Broadly neutralizing antibodies (bNAbs) are the focus of increasing interest for human immunodeficiency virus type 1 (HIV-1) prevention and treatment. Although…”
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Replacement of Antiretroviral Therapy with HIV Broadly Neutralizing Antibodies to Maximize the Effectiveness of Chemotherapy in HIV Patients with Lung Cancer by Atkinson, Ben, Abassi, Abdolrahim, Sajadi, Mohammad M, Tehrani, Zahra Rikhtegaran, Le, Nhut M, Chen, Hegang H, Sausville, Edward, DeVico, Anthony L, Lewis, George K, Fan, Xiaoxuan, Heredia, Alonso

“…Non-small cell lung cancer (NSCLC) is the most fatal non-AIDS defining cancer in people living with HIV (PWH) on antiretroviral therapy (ART). Treatment of…”
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