Search Results - "DeTolla, L. J."

Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation by Shanks, K., Nkyimbeng-Takwi, E.H., Smith, E., Lipsky, M.M., DeTolla, L.J., Scott, D.W., Keegan, A.D., Chapoval, S.P.

“…•We examined the changes in lung responses to allergen in Sema4D−/− and WT mice.•Allergic lung response was downregulated in Sema4D−/− mice as compared to WT…”
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Neuroimmune semaphorin 4A downregulates the severity of allergic response by Nkyimbeng-Takwi, E H, Shanks, K, Smith, E, Iyer, A, Lipsky, M M, DeTolla, L J, Kikutani, H, Keegan, A D, Chapoval, S P

“…To define the role of semaphorin 4A (Sema4A) in allergic response, we employed Sema4A −/− and wild-type (WT) mice in the experimental model of ovalbumin…”
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Neuroimmune semaphorin 4A as a drug and drug target for asthma by Mogie, G., Shanks, K., Nkyimbeng-Takwi, E.H., Smith, E., Davila, E., Lipsky, M.M., DeTolla, L.J., Keegan, A.D., Chapoval, S.P.

“…Neuroimmune semaphorin 4A (Sema4A) has been shown to play an important costimulatory role in T cell activation and regulation of Th1-mediated diseases such as…”
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Subdiaphragmatic vagotomy inhibits intra-abdominal interleukin-1β stimulation of adrenocorticotropin secretion by Kapcala, L.P., He, J.R., Gao, Y., Pieper, J.O., DeTolla, L.J.

“…Although interleukin (IL)-1β activates the hypothalamic-pituitary-adrenal (HPA) axis, the mechanisms by which peripheral IL-1β acutely stimulates…”
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Parenteral gene therapy with p53 inhibits human breast tumors in vivo through a bystander mechanism without evidence of toxicity by Xu, M, Kumar, D, Srinivas, S, Detolla, L J, Yu, S F, Stass, S A, Mixson, A J

“…Mutations of the p53 tumor suppressor gene are the most frequently observed genetic lesion in human cancer. Previously, we found that multiple intravenous…”
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Early Colonic Damage and Invasion of Campylobacter jejuni in Experimentally Challenged Infant Macaca mulatta by Russell, Robert G., O'Donnoghue, Michael, Blake, Daniel C., Zulty, Joseph, DeTolla, Louis J.

“…Experimental challenge studies with Campylobacter jejuni were conducted in 3,5-month-old infant Macaca mulatta. One infant monkey (92-1) was challenged with…”
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Past life on Mars? by DeTolla, L J

“…Abstract only…”
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Mouse Model for Exoerythrocytic Stages of Plasmodium falciparum Malaria Parasite by Sacci, John B., Schriefer, Martin E., Resau, James H., Wirtz, Robert A., Detolla, Louis J., Markham, Richard B., Azad, Abdu F.

“…Research on the exoerythrocytic (EE) stages of human malaria parasites has been hindered because of the lack of an easily available suitable animal model. We…”
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Human immune response to Campylobacter jejuni proteins expressed in vivo by PANIGRAHI, P, LOSONSKY, G, DETOLLA, L. J, GLEEN MORRIS, J. JR

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Serologic response to Helicobacter pylori among children and teenagers in northern Chile by Russell, R G, Wasserman, S S, O'Donnoghue, J M, Taylor, D N, Boslego, J, Moreno, J G, Hopkins, R J, DeTolla, L J, Morris, Jr, J G

“…The serologic response to Helicobacter pylori was determined in 388 children and teenagers living in Iquique, Chile by using an IgG enzyme-linked immunosorbent…”
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Uncommon Campylobacter species in infant Macaca nemestrina monkeys housed in a nursery by RUSSELL, R. G, KIEHLBAUCH, J. A, GEBHART, C. J, DETOLLA, L. J

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A chronic carrierlike state is established in nude mice injected with cloned hepatitis B virus DNA by Feitelson, M A, DeTolla, L J, Zhou, X D

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Development of an in vitro model for study of non-O1 Vibrio cholerae virulence using Caco-2 cells by Panigrahi, P, Tall, B D, Russell, R G, Detolla, L J, Morris, Jr, J G

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Toxicity of the novel animal-derived anticancer agent, VRCTC-310: acute and subchronic studies in beagle dogs by Detolla, Louis J., Stump, Kyle C., Russell, Robert, Viskatis, Luis J., Vidal, Juan G., Newman, Robert A., Etcheverry, Martin A.

“…Acute and subchronic toxicities of VRCTC-310, a combination product of crotoxin (CT) and cardiotoxin (CD), which has shown antitumor activity in vivo, have…”
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A Human Monoclonal Antibody that Protects Mice against Pseudomonas-Induced Pneumonia by Zweerink, Hans J., DetoUa, Louis J., Gammon, Maureen C., Hutchison, Cameron F., Puckett, Jane M., Sigal, Nolan H.

“…X-linked immunodeficient (xid) (CBA/N ♀ × DBA/2 ♂) F1 male mice, when treated with cyclophosphamide, were much more susceptible to challenge with aerosolized…”
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Forum article on nonhuman animal research elicits considerable dialogue by Freeman, A

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Phase II safety and immunogenicity study of type F botulinum toxoid in adult volunteers by Edelman, Robert, Wasserman, Steven S, Bodison, Sacared A, Perry, Judith G, O’Donnoghue, Michael, DeTolla, Louis J

“…An aluminum hydroxide ( alum)-adsorbed, purified, botulinum F toxoid (Bot F) vaccine was manufactured to be administered as a stand-alone monovalent vaccine or…”
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Spectral model of leishmaniasis in congenic strains of mice [Leishmania donovani] by Semprevivo, L. H., DeTolla, L. J., Passmore, H. C., Palczuk, N. C.

“…Nineteen congenic, resistant strains of mice on C57BL/10ScSn genetic background were infected with Leishmania donovani and the course of infection quantitated…”
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Mice deficient in the CXCR2 ligand, CXCL1 (KC/GRO-alpha), exhibit increased susceptibility to dextran sodium sulfate (DSS)-induced colitis by Shea-Donohue, Terez, Thomas, Karen, Cody, M Joshua, Aiping Zhao, Detolla, Louis J, Kopydlowski, Karen M, Fukata, Masayuki, Lira, Sergio A, Vogel, Stefanie N

“…The role of TLRs and MyD88 in the maintenance of gut integrity in response to dextran sodium sulfate (DSS)-induced colitis was demonstrated recently and led to…”
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Genetic control of acquired resistance to visceral leishmaniasis in mice by DeTolla, Jr, L J, Semprevivo, L H, Palczuk, N C, Passmore, H C

“…A series of H-2 and non-H-2 congenic resistant (CR) strains on a C57BL/10Sn background were infected with 10(7) amastigotes of Leishmania donovani. Non-H-2…”
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