Search Results - "DeStefano, J"

Xeno-Nucleic Acid (XNA) 2’-Fluoro-Arabino Nucleic Acid (FANA) Aptamers to the Receptor-Binding Domain of SARS-CoV-2 S Protein Block ACE2 Binding by Alves Ferreira-Bravo, Irani, DeStefano, Jeffrey J.

“…The causative agent of COVID-19, SARS-CoV-2, gains access to cells through interactions of the receptor-binding domain (RBD) on the viral S protein with…”
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Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation by Das, Kalyan, Martinez, Sergio E., DeStefano, Jeffrey J., Arnold, Eddy

“…The initiation phase of HIV reverse transcription has features that are distinct from its elongation phase. The first structure of a reverse transcription…”
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Where Biology and Traditional Polymers Meet: The Potential of Associating Sequence-Defined Polymers for Materials Science by DeStefano, Audra J, Segalman, Rachel A, Davidson, Emily C

“…Polymers with precisely defined monomeric sequences present an exquisite tool for controlling material properties by harnessing both the robustness of…”
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Performance characteristics of new superficially porous particles by DeStefano, Joseph J., Schuster, Stephanie A., Lawhorn, Jason M., Kirkland, Joseph J.

“…► h of 5μm Fused-Core particles is lower than smaller Fused-Core particles. ► The thinner shell for the Fused-Core particles results in flatter van Deemter…”
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Inhibition of SARS-CoV-2 infection in human airway epithelium with a xeno-nucleic acid aptamer by Razi, Niayesh, Li, Weizhong, Ignacio, Maxinne A, Loube, Jeffrey M, Agostino, Eva L, Zhu, Xiaoping, Scull, Margaret A, DeStefano, Jeffrey J

“…SARS-CoV-2, the agent responsible for the COVID-19 pandemic, enters cells through viral spike glycoprotein binding to the cellular receptor,…”
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Effects of Amphiphilic Polypeptoid Side Chains on Polymer Surface Chemistry and Hydrophilicity by Barry, Mikayla E, Aydogan Gokturk, Pinar, DeStefano, Audra J, Leonardi, Amanda K, Ober, Christopher K, Crumlin, Ethan J, Segalman, Rachel A

“…Polymers are commonly used in applications that require long-term exposure to water and aqueous mixtures, serving as water purification membranes, marine…”
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Workshop Report and Follow-Up—AAPS Workshop on Current Topics in GLP Bioanalysis: Assay Reproducibility for Incurred Samples—Implications of Crystal City Recommendations by Fast, Douglas M., Kelley, Marian, Viswanathan, C. T., O’Shaughnessy, Jacqueline, King, S. Peter, Chaudhary, Ajai, Weiner, Russell, DeStefano, Anthony J., Tang, Daniel

“…The Conference Report of the 3rd AAPS/FDA Bioanalytical Workshop (Crystal City III) endorsed the concept that assay methods supporting bioanalytical data in…”
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Selection of Primer-Template Sequences That Bind with Enhanced Affinity to Vaccinia Virus E9 DNA Polymerase by DeStefano, Jeffrey J, Iseni, Frédéric, Tarbouriech, Nicolas

“…A modified SELEX (Systematic Evolution of Ligands by Exponential Enrichment) pr,otocol (referred to as PT SELEX) was used to select primer-template (P/T)…”
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Structure of HIV‐1 reverse transcriptase bound to a novel 38‐mer hairpin template‐primer DNA aptamer by Miller, Matthew T., Tuske, Steve, Das, Kalyan, DeStefano, Jeffrey J., Arnold, Eddy

“…The development of a modified DNA aptamer that binds HIV‐1 reverse transcriptase (RT) with ultra‐high affinity has enabled the X‐ray structure determination of…”
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Machine learning of superconducting critical temperature from Eliashberg theory by Xie, S. R., Quan, Y., Hire, A. C., Deng, B., DeStefano, J. M., Salinas, I., Shah, U. S., Fanfarillo, L., Lim, J., Kim, J., Stewart, G. R., Hamlin, J. J., Hirschfeld, P. J., Hennig, R. G.

“…The Eliashberg theory of superconductivity accounts for the fundamental physics of conventional superconductors, including the retardation of the interaction…”
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Conformational States of HIV‑1 Reverse Transcriptase for Nucleotide Incorporation vs PyrophosphorolysisBinding of Foscarnet by Das, Kalyan, Balzarini, Jan, Miller, Matthew T, Maguire, Anita R, DeStefano, Jeffrey J, Arnold, Eddy

“…HIV-1 reverse transcriptase (RT) catalytically incorporates individual nucleotides into a viral DNA strand complementing an RNA or DNA template strand; the…”
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The art and science of forming packed analytical high-performance liquid chromatography columns by Kirkland, J.J., DeStefano, J.J.

“…Columns of packed particles still are the most popular devices for high-performance liquid chromatography (HPLC) separations because of their great utility,…”
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Immune Focusing and Enhanced Neutralization Induced by HIV-1 gp140 Chemical Cross-Linking by Schiffner, T, Kong, L, Duncan, C J A, Back, J W, Benschop, J J, Shen, X, Huang, P S, Stewart-Jones, G B, DeStefano, J, Seaman, M S, Tomaras, G D, Montefiori, D C, Schief, W R, Sattentau, Q J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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HIV Reverse Transcriptase Pre-Steady-State Kinetic Analysis of Chain Terminators and Translocation Inhibitors Reveals Interactions between Magnesium and Nucleotide 3′-OH by Dilmore, Christopher R, DeStefano, Jeffrey J

“…Deoxythymidine triphosphate analogues with various 3′ substituents in the sugar ring (−OH (dTTP)), −H, −N3, −NH2, −F, −O–CH3, no group…”
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Quantitative bioanalytical methods validation and implementation: best practices for chromatographic and ligand binding assays by Viswanathan, C T, Bansal, Surendra, Booth, Brian, DeStefano, Anthony J, Rose, Mark J, Sailstad, Jeffrey, Shah, Vinod P, Skelly, Jerome P, Swann, Patrick G, Weiner, Russell

“…The Third AAPS/FDA Bioanalytical Workshop, entitled "Quantitative Bioanalytical Methods Validation and Implementation: Best Practices for Chromatographic and…”
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Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT) by Harrison, Jerry Joe E K, Tuske, Steve, Das, Kalyan, Ruiz, Francesc X, Bauman, Joseph D, Boyer, Paul L, DeStefano, Jeffrey J, Hughes, Stephen H, Arnold, Eddy

“…In most cases, proteolytic processing of the retroviral Pol portion of the Gag-Pol polyprotein precursor produces protease (PR), reverse transcriptase (RT),…”
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DNA aptamers to human immunodeficiency virus reverse transcriptase selected by a primer-free SELEX method: characterization and comparison with other aptamers by Lai, Yi-Tak, DeStefano, Jeffrey J

“…A 30-nucleotide DNA aptamer (5'-AGGAAGGCTTTAGGTCTGAGATCTCGGAAT-3', denoted PF1) selected for high affinity to human immunodeficiency virus reverse…”
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Detection of cyclic diguanylate G-octaplex assembly and interaction with proteins by Lieberman, Ori J, DeStefano, Jeffrey J, Lee, Vincent T

“…Bacterial signaling networks control a wide variety of cellular processes including growth, metabolism, and pathogenesis. Bis-(3'-5')-cyclic dimeric guanosine…”
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Duplex structural differences and not 2'-hydroxyls explain the more stable binding of HIV-reverse transcriptase to RNA-DNA versus DNA-DNA by Olimpo, Jeffrey T, DeStefano, Jeffrey J

“…Human immunodeficiency virus reverse transcriptase (HIV-RT) binds more stably in binary complexes with RNA-DNA versus DNA-DNA. Current results indicate that…”
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Poliovirus Protein 3AB Displays Nucleic Acid Chaperone and Helix-Destabilizing Activities by DESTEFANO, Jeffrey J, TITILOPE, Oduyebo

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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