Search Results - "DeSimone, Robert W"

Imidazo[1,2-a]pyrazine diaryl ureas: Inhibitors of the receptor tyrosine kinase EphB4 by Mitchell, Scott A., Danca, Mihaela Diana, Blomgren, Peter A., Darrow, James W., Currie, Kevin S., Kropf, Jeffrey E., Lee, Seung H., Gallion, Steven L., Xiong, Jin-Ming, Pippin, Douglas A., DeSimone, Robert W., Brittelli, David R., Eustice, David C., Bourret, Aaron, Hill-Drzewi, Melissa, Maciejewski, Patricia M., Elkin, Lisa L.

“…The identification of imidazo[1,2-a]pyrazine diarylureas as potent inhibitors of the receptor tyrosine kinaseEphB4 is reported. Inhibition of receptor tyrosine…”
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The use of combi chem, high-speed analog chemistry and HTS in drug discovery by DeSimone, Robert W

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New Syntheses of the C,D-Ring Pyrromethenones of Phytochrome and Phycocyanin by Jacobi, Peter A, DeSimone, Robert W, Ghosh, Indranath, Guo, Jiasheng, Leung, Sam H, Pippin, Douglas

“…Pyrromethenone 7, the C,D-ring segment of phytochrome (Pr, 4), has been prepared in an efficient fashion employing three new strategies. Each of these has…”
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Substituted 3-(2-benzoxazyl)-benzimidazol-2-(1H)-ones : A new class of GABAA brain receptor ligands by DESIMONE, Robert W, BLUM, Charles A

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Singlet oxygen oxidation of bipyrroles: total synthesis of d,l- and meso-isochrysohermidin by Wasserman, Harry H, DeSimone, Robert W, Boger, Dale L, Baldino, Carmen M

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Singlet Oxygen Reactions from the Adducts of Ozone with Heterocyclic Substrates by Wasserman, Harry H, Yoo, Ji Uk, DeSimone, Robert W

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Bis-heteroannulation. 15. Enantiospecific syntheses of (+)- and (-)-norsecurinine by Jacobi, Peter A, Blum, Charles A, DeSimone, Robert W, Udodong, Uko E. S

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Singlet oxygen in synthesis. Formation of d, l- and meso-isochrysohermidin from a 3,3′-bipyrrole precursor by Wasserman, Harry H., Rotello, Vincent M., Frechette, Roger, DeSimone, Robert W., Yoo, Ji Uk, Baldino, Carmen M.

“…A synthesis of the d, l and meso forms of isochrysohermidin 3 is outlined which employs the singlet oxygen oxidation of pyrroles as the key step. The bipyrrole…”
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Substituted 3-(2-benzoxazyl)-benzimidazol-2-(1 H)-ones: A new class of GABA A brain receptor ligands by DeSimone, Robert W., Blum, Charles A.

“…A novel class of potent benzodiazepine receptor (BZR) ligands has been designed and synthesized aided by molecular modeling of known benzodiazepine ligands…”
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Singlet oxygen oxidation of bipyrroles : total synthesis of d,l- and meso-isochrysohermidin by WASSERMAN, H. H, DESIMONE, R. W, BOGER, D. L, BALDINO, C. M

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Singlet Oxygen in Synthesis. Formation of d,l- and meso-Isochrysohermidin from a 3,3′-Bipyrrole Precursor by Wasserman, H

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