Search Results - "DeSimone, D W"

Regulation of cell polarity, radial intercalation and epiboly in Xenopus: novel roles for integrin and fibronectin by Marsden, M, DeSimone, D W

“…Fibronectin (FN) is reported to be important for early morphogenetic movements in a variety of vertebrate embryos, but the cellular basis for this requirement…”
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Identification and Characterization of Thrombospondin-4, a New Member of the Thrombospondin Gene Family by Lawler, Jack, Duquette, Mark, Whittaker, Charles A., Adams, Josephine C., McHenry, Katherine, DeSimone, Douglas W.

“…A new member of the thrombospondin gene family, designated thrombospondin-4, has been identified in the Xenopus laevis genome. The predicted amino acid…”
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Xenopus Embryonic Cell Adhesion to Fibronectin: Position-Specific Activation of RGD/Synergy Site-Dependent Migratory Behavior at Gastrulation by Ramos, Joe W., DeSimone, Douglas W.

“…During Xenopus laevis gastrulation, the basic body plan of the embryo is generated by movement of the marginal zone cells of the blastula into the blastocoel…”
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Integrin-ECM Interactions Regulate Cadherin-Dependent Cell Adhesion and Are Required for Convergent Extension in Xenopus by Marsden, Mungo, DeSimone, Douglas W.

“…Background: Convergence extension movements are conserved tissue rearrangements implicated in multiple morphogenetic events. While many of the cell behaviors…”
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Xenopus laevis integrins. Structural conservation and evolutionary divergence of integrin beta subunits by DeSimone, D W, Hynes, R O

“…We report the sequences of cDNA clones for two different integrin beta subunits isolated from a Xenopus laevis neurula cDNA library. mRNAs corresponding to…”
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Integrin alpha 5 beta 1 supports the migration of Xenopus cranial neural crest on fibronectin by Alfandari, D, Cousin, H, Gaultier, A, Hoffstrom, B G, DeSimone, D W

“…During early embryonic development, cranial neural crest cells emerge from the developing mid- and hindbrain. While numerous studies have focused on integrin…”
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Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration by Alfandari, Dominique, Cousin, Hélène, Gaultier, Alban, Smith, Katherine, White, Judith M, Darribère, Thierry, DeSimone, Douglas W

“…Background: Cranial neural-crest (CNC) cells originate from the lateral edge of the anterior neuroepithelium and migrate to form parts of the peripheral…”
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Multicellular computer simulation of morphogenesis: blastocoel roof thinning and matrix assembly in Xenopus laevis by Longo, Diane, Peirce, Shayn M., Skalak, Thomas C., Davidson, Lance, Marsden, Mungo, Dzamba, Bette, DeSimone, Douglas W.

“…In the blastocoel roof (BCR) of the Xenopus laevis embryo, epibolic movements are driven by the radial intercalation of deep cell layers and the coordinate…”
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Fibronectins, their fibrillogenesis, and in vivo functions by Schwarzbauer, Jean E, DeSimone, Douglas W

“…Fibronectin (FN) is a multidomain protein with the ability to bind simultaneously to cell surface receptors, collagen, proteoglycans, and other FN molecules…”
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Adhesion and matrix in vertebrate development by DeSimone, D W

“…The extracellular matrix supports the adhesion and migration of cells during morphogenesis and influences cell differentiation. Cell interactions with the…”
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Active Zones on Motor Nerve Terminals Contain alpha 3 beta 1 Integrin by Cohen, M W, Hoffstrom, B G, DeSimone, D W

“…Active zones are the sites along nerve terminals where synaptic vesicles dock and undergo calcium-dependent exocytosis during synaptic transmission. Here we…”
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ADAM 13: a novel ADAM expressed in somitic mesoderm and neural crest cells during Xenopus laevis development by Alfandari, D, Wolfsberg, T G, White, J M, DeSimone, D W

“…Embryonic development involves a series of cell adhesive interactions that provide mechanical and instructive information required for morphogenesis. The ADAMs…”
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Integrin alpha subunit mRNAs are differentially expressed in early Xenopus embryos by WHITTAKER, C. A, DESIMONE, D. W

“…Adhesion of cells to extracellular matrix proteins is mediated, in large part, by transmembrane receptors of the integrin family. The identification of…”
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Role of the extracellular matrix in amphibian gastrulation by Johnson, K E, Boucaut, J C, DeSimone, D W

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Integrin alpha 6 expression is required for early nervous system development in Xenopus laevis by Lallier, T E, Whittaker, C A, DeSimone, D W

“…The integrin alpha 6 subunit pairs with both the beta 1 and beta 4 subunits to form a subfamily of laminin receptors. Here we report the cDNA cloning and…”
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Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos by DeSimone, Douglas W., Norton, Pamela A., Hynes, Richard O.

“…Sequence analysis of cDNA clones encoding fibronectin (FN) from Xenopus laevis reveals extensive amino acid identities with other vertebrate FNs, including the…”
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Integrin-dependent adhesive activity is spatially controlled by inductive signals at gastrulation by Ramos, J W, Whittaker, C A, DeSimone, D W

“…Integrins mediate cell-ECM interactions essential for morphogenesis, however, the extent to which integrin adhesive activities are regulated in the embryo has…”
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Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin by Tamkun, J W, DeSimone, D W, Fonda, D, Patel, R S, Buck, C, Horwitz, A F, Hynes, R O

“…We describe the isolation, characterization, and sequence of cDNA clones encoding one subunit of the complex of membrane glycoproteins that forms part of the…”
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Separation of Neural Induction and Neurulation in Xenopus by Lallier, Thomas E, DeSimone, Douglas W

“…Cellular interactions with laminin are important for numerous morphogenetic events. In Xenopus, the first of these is neurulation. The integrin α6 subunit…”
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The integrin family of cell surface receptors by DeSimone, D W, Stepp, M A, Patel, R S, Hynes, R O

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