Search Results - "DeSilva, D R"

Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation by DeSilva, DR, Urdahl, KB, Jenkins, MK

“…Murine Th1 clones that receive signals through their TCR in the absence of APC-derived co-stimulatory signals do not produce IL-2 and instead become anergic,…”
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Inhibition of Mitogen-Activated Protein Kinase Kinase Blocks T Cell Proliferation But Does Not Induce or Prevent Anergy by DeSilva, Dimuthu R, Jones, Elizabeth A, Favata, Margaret F, Jaffee, Bruce D, Magolda, Ronald L, Trzaskos, James M, Scherle, Peggy A

“…Three mitogen-activated protein kinase pathways are up-regulated during the activation of T lymphocytes, the extracellular signal-regulated kinase (ERK), Jun…”
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Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways by DeSilva, D R, Feeser, W S, Tancula, E J, Scherle, P A

“…T helper type 1 cells (Th1) become anergic when stimulated through the antigen receptor in the absence of costimulation. They do not produce IL-2 or…”
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Defective transcription of the IL-2 gene is associated with impaired expression of c-Fos, FosB, and JunB in anergic T helper 1 cells by Mondino, A, Whaley, CD, DeSilva, DR, Li, W, Jenkins, MK, Mueller, DL

“…Anergic CD4+ Th cells do not produce IL-2 when challenged with Ag-pulsed accessory cells because of a transcriptional defect. In this work, we report that…”
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The p38 Mitogen-Activated Protein Kinase Pathway in Activated and Anergic Th1 Cells by Desilva, Dimuthu R., Jones, Elizabeth A., Feeser, Wendi S., Manos, Elizabeth J., Scherle, Peggy A.

“…Stimulation of T cells through the TCR leads to activation of the mitogen-activated protein kinase (MAPK) family members ERK (extracellular signal-regulated…”
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Reduction in vulnerability to ventricular fibrillation by bromocriptine, a dopamine agonist by Falk, R H, Desilva, R D, Lown, B

“…The effect of a dopamine agonist, bromocriptine, on ventricular fibrillation (VF) threshold was studied in anaesthetised dogs. Bromocriptine produced an…”
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Costimulating factors and signals relevant for antigen presenting cell function by Jenkins, M K, DeSilva, D R, Johnson, J G, Norton, S D

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Anergic T cells are defective in both jun NH sub(2)-terminal kinase and mitogen-activated protein kinase signaling pathways by DeSilva, DR, Feeser, W S, Tancula, E J, Scherle, P A

“…T helper type 1 cells (Th1) become anergic when stimulated through the antigen receptor in the absence of costimulation. They do not produce IL-2 or…”
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MRI of a hibernoma by COOK, M. A, STERN, M, DE SILVA, R. D

“…Hibernomas are benign tumors derived from brown fat that most often present as painless, slowly enlarging masses in the interscapular region. Because these…”
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Water-soluble contrast medium in the localisation of cord and dural stab wounds by Sutton, D, DeSilva, R D

“…Two cases are reported of dorsal stab wounds involving the spinal cord. In both cases the site of the dural tear and cord damage were accurately localised by…”
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Computed tomography in deep-seated peripheral neurofibromas by Sutton, D, Al-Kutoubi, M A, DeSilva, R D, Thomas, D

“…Seven peripheral deep-seated neurofibromas in five patients were examined by computed tomography (CT). This proved to be the most helpful investigation for…”
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Volvular epilepsy associated with line-of-migration abnormality: a case report by Stern, M J, Cook, M A, Shramek, J K, de Silva, R D, Raguthu, S

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