Search Results - "DeSesso, John M."

Vascular ontogeny within selected thoracoabdominal organs and the limbs by DeSesso, John M.

“…•Blood vessels are an integral part of all organs.•The developing vascular system contributes to the form and pattern of organs.•The modes of blood vessel…”
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Commentary: Considering intrauterine location in a model of fetal growth restriction after maternal titanium dioxide nanoparticle inhalation by DeSesso, John M, Wise, L David

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The placenta, transfer of immunoglobulins, and safety assessment of biopharmaceuticals in pregnancy by DeSesso, John M., Williams, Amy L., Ahuja, Arshiya, Bowman, Christopher J., Hurtt, Mark E.

“…Anatomical and developmental differences of the parental-offspring interface among experimental animals and humans throughout gestation are reviewed focusing…”
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Postnatal growth and morphological development of the brain: a species comparison by Watson, Rebecca E., DeSesso, John M., Hurtt, Mark E., Cappon, Gregg D.

“…The objective of this report is to summarize the available literature regarding the postnatal growth and morphological development of the brain and compare the…”
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Overview: Using Mode of Action and Life Stage Information to Evaluate the Human Relevance of Animal Toxicity Data by Seed, Jennifer, Carney, Edward W., Corley, Richard A., Crofton, Kevin M., DeSesso, John M., Foster, Paul M. D., Kavlock, Robert, Kimmel, Gary, Klaunig, James, Meek, M. E., Preston, R. Julian, Slikker, William, Tabacova, Sonia, Williams, Gary M., Wiltse, Jeanette, Zoeller, R. Thomas, Fenner-Crisp, Penelope, Patton, Dorothy E.

“…A complete mode of action human relevance analysis-as distinct from mode of action (MOA) analysis alone-depends on robust information on the animal MOA, as…”
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Comparative anatomy, pre‐ and postnatal changes during the development and maturation of the small intestine: Life‐stage influences on exposure by DeSesso, John M.

“…The gastrointestinal (GI) system absorbs nutrients and xenobiotics, excretes waste, and performs immunologic and endocrine functions. The subdivisions of the…”
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Extended one-generation reproductive toxicity study of food-grade titanium dioxide E171 with emphasis on reproductive and endocrine endpoints by Battersby, Rodger V., Adam, Janine, Williams, Amy L., DeSesso, John M.

“…Food-grade titanium dioxide E171 was administered in feed to Sprague Dawley rats in an extended one-generation reproductive toxicity (EOGRT) study (OECD Test…”
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Developmental and Reproductive Outcomes in Humans and Animals After Glyphosate Exposure: A Critical Analysis by Williams, Amy Lavin, Watson, Rebecca E., DeSesso, John M.

“…Glyphosate is the active ingredient of several widely used herbicide formulations. Glyphosate targets the shikimate metabolic pathway, which is found in plants…”
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The arrogance of teratology: A brief chronology of attitudes throughout history by DeSesso, John M.

“…While the discipline of Teratology has existed for about 60 years, there has been a deep interest in the causes of human malformations for millennia. Absent…”
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Of embryos and tumors: Cyclopia and the relevance of mechanistic teratology by DeSesso, John M.

“…Embryos and tumors share several characteristics, but embryos differ from tumors in their coordination of cellular‐ and tissue‐level processes, including…”
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Reminiscences of the 36th president by DeSesso, John M.

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Comment on “Concentrations of vanadium in urine and seminal plasma in relation to semen quality parameters, spermatozoa DNA damage and serum hormone levels,” by Wang et al by Williams, Amy L., Gollapudi, Bhaskar, Pace, Nelson D., DeSesso, John M.

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Estimation of cancer risks and benefits associated with a potential increased consumption of fruits and vegetables by Reiss, Richard, Johnston, Jason, Tucker, Kevin, DeSesso, John M., Keen, Carl L.

“…► A cancer incidence cost–benefit analysis is conducted for fruits and vegetables. ► About 20,000 cancer cases could be avoided by increasing consumption by…”
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Comments on “Maternal–fetal safety evaluation of an aqueous extract of Casearia sylvestris [AECS] leaves in rats” (Nagaoka et al., 2023 [DOI: 10.1002/bdr2.2257]) by Wise, L. David, DeSesso, John M.

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Mechanisms regulating toxicant disposition to the embryo during early pregnancy: An interspecies comparison by Carney, Edward W., Scialli, Anthony R., Watson, Rebecca E., DeSesso, John M.

“…The dose of toxicant reaching the embryo is a critical determinant of developmental toxicity, and is likely to be a key factor responsible for interspecies…”
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A critical look at adjusted fetal weights in rats by Wise, L. David, DeSesso, John M.

“…Background A new derived (i.e., calculated) endpoint of developmental toxicology has appeared in a very few studies since 1990. This endpoint is adjusted mean…”
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Bone development in laboratory mammals used in developmental toxicity studies by DeSesso, John M., Scialli, Anthony R.

“…Evaluation of the skeleton in laboratory animals is a standard component of developmental toxicology testing. Standard methods of performing the evaluation…”
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Revisiting the testicular toxicity of cyanide: Assessment of the new and existing literature by Williams, Amy Lavin, DeSesso, John M.

“…Background Based on new testing, we re‐assess U.S. EPA and California OEHHA conclusions regarding male reproductive toxicity associated with cyanide exposure…”
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Comment on Sweeting and Wells (2015) by White, Tacey, Williams, Amy, DeSesso, John M.

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Gestational/Perinatal chlorpyrifos exposure is not associated with autistic-like behaviors in rodents by Williams, Amy Lavin, DeSesso, John M.

“…Abstract Although animal models cannot exactly replicate human psychiatric disorders, they may be useful to investigate whether the behaviors associated with…”
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