Search Results - "DeQuach, Jessica A"
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Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture
Published in PloS one (27-09-2010)“…The native extracellular matrix (ECM) consists of a highly complex, tissue-specific network of proteins and polysaccharides, which help regulate many cellular…”
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First-in-Man Study of a Cardiac Extracellular Matrix Hydrogel in Early and Late Myocardial Infarction Patients
Published in JACC. Basic to translational science (01-10-2019)“…Visual Abstract…”
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Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering
Published in Biomaterials (01-10-2009)“…Abstract Myocardial tissue lacks the ability to significantly regenerate itself following a myocardial infarction, thus tissue engineering strategies are…”
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Safety and efficacy of an injectable extracellular matrix hydrogel for treating myocardial infarction
Published in Science translational medicine (20-02-2013)“…New therapies are needed to prevent heart failure after myocardial infarction (MI). As experimental treatment strategies for MI approach translation, safety…”
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A naturally derived cardiac extracellular matrix enhances cardiac progenitor cell behavior in vitro
Published in Acta biomaterialia (01-12-2012)“…Myocardial infarction (MI) produces a collagen scar, altering the local microenvironment and impeding cardiac function. Cell therapy is a promising therapeutic…”
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Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds
Published in Tissue engineering. Part A (01-11-2011)“…The extracellular matrix (ECM) plays important roles in influencing cellular behavior such as attachment, differentiation, and proliferation. However, in…”
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Injectable skeletal muscle matrix hydrogel promotes neovascularization and muscle cell infiltration in a hindlimb ischemia model
Published in European cells & materials (05-06-2012)“…Peripheral artery disease (PAD) currently affects approximately 27 million patients in Europe and North America, and if untreated, may progress to the stage of…”
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Human cardiomyogenesis and the need for systems biology analysis
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01-11-2011)“…Cardiovascular disease remains the leading cause of death in the Western world and myocardial infarction is one of the primary facets of this disease. The…”
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Injectable myocardial matrix as a scaffold for myocardial tissue engineering
Published in 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (01-01-2009)“…Current injectable materials utilized in myocardial tissue engineering have been borrowed from other tissue engineering applications and have not been…”
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Enhanced Proliferation and Cardiogenic Differentiation of Cardiac Progenitor Cells Treated with a Naturally Derived Cardiac Extracellular Matrix
Published in The FASEB journal (01-04-2012)“…Abstract only Adverse remodeling of the myocardium after myocardial infarction speeds progression to heart failure. Some of the major shortcomings in cell…”
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Abstract P031: Enhanced Cardiac Progenitor Cell Function and Differentiation in a Naturally Derived Extracellular Matrix
Published in Circulation research (09-12-2011)“…Abstract only Cardiovascular disease, including myocardial infarction, is a leading cause of death worldwide. Though several pharmacological treatments for…”
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Abstract 344: Naturally Derived Cardiac Extracellular Matrix for Cardiac Progenitor Cell Therapy
Published in Circulation research (03-08-2012)“…Abstract only Cardiovascular disease is the leading cause of death in the United States. Following acute myocardial infarction, there is dramatic myocyte loss,…”
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