Search Results - "DePorter, Sandra M."
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Engineered M13 Bacteriophage Nanocarriers for Intracellular Delivery of Exogenous Proteins to Human Prostate Cancer Cells
Published in Bioconjugate chemistry (17-09-2014)“…The size, well-defined structure, and relatively high folding energies of most proteins allow them to recognize disease-relevant receptors that present a…”
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Journal Article -
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N-Nosyl oxaziridines as terminal oxidants in copper(II)-catalyzed olefin oxyaminations
Published in Tetrahedron letters (06-10-2010)“…We report that N-4-nosyl-3-phenyloxaziridine is an effective terminal oxidant for copper(II)-catalyzed oxyamination recently developed in our labs. This…”
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Journal Article -
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A Nanobody Activation Immunotherapeutic that Selectively Destroys HER2-Positive Breast Cancer Cells
Published in Chembiochem : a European journal of chemical biology (01-01-2016)“…We report a rationally designed nanobody activation immunotherapeutic that selectively redirects anti‐dinitrophenyl (anti‐DNP) antibodies to the surface of…”
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Journal Article -
4
Methods for identifying and characterizing interactions involving RNA
Published in Tetrahedron (28-10-2012)“…[Display omitted]…”
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Journal Article -
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Back Cover: A Nanobody Activation Immunotherapeutic that Selectively Destroys HER2-Positive Breast Cancer Cells (ChemBioChem 2/2016)
Published in Chembiochem : a European journal of chemical biology (15-01-2016)“…The back cover picture shows a killer nanobody. Features unique to proteins allow these biomolecules to recognize disease‐relevant structures that challenge or…”
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Journal Article -
6
Mutagenesis modulates the uptake efficiency, cell-selectivity, and functional enzyme delivery of a protein transduction domain
Published in Molecular bioSystems (01-01-2014)“…Alanine scanning mutagenesis of a recently reported prostate cancer cell-selective Protein Transduction Domain (PTD) was used to assess the specific…”
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Journal Article -
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A Protein Transduction Domain with Cell Uptake and Selectivity Profiles that Are Controlled by Multivalency Effects
Published in Chemistry & biology (21-03-2013)“…Protein transduction domains (PTDs) are reagents that facilitate the delivery of diverse cargo to the interior of mammalian cells. We identified a PTD called…”
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A one-pot synthesis of micron-sized and nanoscale poly(N-acryloxysuccinimide-co-N-vinylpyrrolidone) particles
Published in Tetrahedron letters (21-11-2012)“…We report a one-pot synthesis of well-defined micron-sized or nanoscale poly(N-acryloxysuccinimide-co-N-vinylpyrrolidone) particles. We show that these…”
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Journal Article -
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Engineering bacteriophage nanocarriers for targeted delivery of protein reagents to prostate cancer cells
Published 01-01-2014“…Proteinaceous reagents, including antibodies and synthetic proteins, have become some of the most effective reagents for targeted treatment and diagnosis of…”
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Dissertation