Search Results - "DeNoel, Philippe"

Innovation Partnership for a Roadmap on Vaccines in Europe (IPROVE): A vision for the vaccines of tomorrow by Medaglini, Donata, De Azero, Magdalena R., Leroy, Odile, Bietrix, Florence, Denoel, Philippe

“…•To keep European leadership in vaccines, EU experts drafted a roadmap for future vaccine research.•IPROVE prioritises future vaccine development within a…”
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Additive and Synergistic Bactericidal Activity of Antibodies Directed against Minor Outer Membrane Proteins of Neisseria meningitidis by Weynants, Vincent E, Feron, Christiane M, Goraj, Karine K, Bos, Martine P, Denoël, Philippe A, Verlant, Vincent G, Tommassen, Jan, Peak, Ian R.A, Judd, Ralph C, Jennings, Michael P, Poolman, Jan T

“…Neisseria meningitidis serogroup B is a major cause of bacterial meningitis in younger populations. The available vaccines are based on outer membrane vesicles…”
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Systematic Evaluation of Kinetics and Distribution of Muscle and Lymph Node Activation Measured by 18F-FDG- and 11C-PBR28-PET/CT Imaging, and Whole Blood and Muscle Transcriptomics After Immunization of Healthy Humans With Adjuvanted and Unadjuvanted Vaccines by Win, Zarni, Weiner 3rd, January, Listanco, Allan, Patel, Neva, Sharma, Rohini, Greenwood, Aldona, Maertzdorf, Jeroen, Mollenkopf, Hans-Joachim, Pizzoferro, Kat, Cole, Thomas, Bodinham, Caroline L., Kaufmann, Stefan H. E., Denoel, Philippe, Del Giudice, Giuseppe, Lewis, David J. M.

“…Systems vaccinology has been applied to detect signatures of human vaccine induced immunity but its ability, together with high definition in vivo clinical…”
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Preclinical Evaluation of the Pht Proteins as Potential Cross-Protective Pneumococcal Vaccine Antigens by Godfroid, Fabrice, Hermand, Philippe, Verlant, Vincent, Denoël, Philippe, Poolman, Jan T

“…Current pneumococcal vaccines are composed of capsular polysaccharides (PS) of various serotypes, either as free PS or as protein-PS conjugates. The use of…”
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Role of Pht proteins in attachment of Streptococcus pneumoniae to respiratory epithelial cells by Kallio, Anna, Sepponen, Kirsi, Hermand, Philippe, Denoël, Philippe, Godfroid, Fabrice, Melin, Merit

“…Pneumococcal adherence to mucosal surfaces is a critical step in nasopharyngeal colonization, but so far few pneumococcal adhesins involved in the interaction…”
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A Protein E-PilA Fusion Protein Shows Vaccine Potential against Nontypeable Haemophilus influenzae in Mice and Chinchillas by Ysebaert, Carine, Denoël, Philippe, Weynants, Vincent, Bakaletz, Lauren O, Novotny, Laura A, Godfroid, Fabrice, Hermand, Philippe

“…PE-PilA is a fusion protein composed of immunologically relevant parts of protein E (PE) and the majority subunit of the type IV pilus (PilA), two major…”
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PERISCOPE: road towards effective control of pertussis by Diavatopoulos, Dimitri A., Mills, Kingston H.G., Kester, Kent E., Kampmann, Beate, Silerova, Marcela, Heininger, Ulrich, van Dongen, Jacques J.M., van der Most, Robbert G., Huijnen, Martijn A., Siena, Emilio, Mielcarek, Nathalie, Ochs, Martina M., Denoël, Philippe, Berbers, Guy, Buisman, Annemarie M., de Jonge, Marien I., Fenwick, Craig, Gorringe, Andrew, He, Qiushui, Kelly, Dominic, Le Grand, Roger, Locht, Camille, Mascart, Françoise, Mertsola, Jussi, Orfao, Alberto, Pantaleo, Giuseppe, Pollard, Andrew J., Preston, Andrew, Read, Robert, Sebo, Peter, van Els, Cecile, Vecerek, Branislav, Londoño-Hayes, Patricia, de Groot, Ronald

“…The resurgence and changing epidemiology of pertussis in high-income countries, the high infant mortality caused by pertussis in low-income countries, and the…”
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A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae by Denoël, Philippe, Philipp, Mario T, Doyle, Lara, Martin, Dale, Carletti, Georges, Poolman, Jan T

“…Abstract Infections caused by Streptococcus pneumoniae are a major cause of mortality throughout the world. Protein-based pneumococcal vaccines are envisaged…”
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Protein Antigens Increase the Protective Efficacy of a Capsule-Based Vaccine against Staphylococcus aureus in a Rat Model of Osteomyelitis by Lattar, Santiago M, Noto Llana, Mariángeles, Denoël, Philippe, Germain, Sophie, Buzzola, Fernanda R, Lee, Jean C, Sordelli, Daniel O

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Preclinical evaluation of a chemically detoxified pneumolysin as pneumococcal vaccine antigen by Hermand, Philippe, Vandercammen, Annick, Mertens, Emmanuel, Di Paolo, Emmanuel, Verlant, Vincent, Denoël, Philippe, Godfroid, Fabrice

“…The use of protein antigens able to protect against the majority of Streptococcus pneumoniae serotypes is envisaged as stand-alone and/or complement to the…”
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Quality of the Haemophilus influenzae Type b (Hib) Antibody Response Induced by Diphtheria-Tetanus-Acellular Pertussis/Hib Combination Vaccines by Denoël, Philippe A., Goldblatt, David, de Vleeschauwer, Isabel, Jacquet, Jeanne-Marie, Pichichero, Michael E., Poolman, Jan T.

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Assessment of the Nasopharyngeal Bacterial Flora of Rhesus Macaques: Moraxella, Neisseria, Haemophilus, and Other Genera by BOWERS, Lisa C, PURCELL, Jeanette E, PLAUCHE, Gail B, DENOEL, Philippe A, LOBET, Yves, PHILIPP, Mario T

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Abrogation of nontypeable Haemophilus influenzae Protein D function reduces phosphorylcholine decoration, adherence to airway epithelial cells, and fitness in a chinchilla model of otitis media by Johnson, Ryan W, McGillivary, Glen, Denoël, Philippe, Poolman, Jan, Bakaletz, Lauren O

“…Abstract The pneumococcal polysaccharide conjugate vaccine which includes a nonacylated protein D carrier from Haemophilus influenzae has been recently…”
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Combined protective effects of anti-PhtD and anti-pneumococcal polysaccharides by Denoël, Philippe, Godfroid, Fabrice, Hermand, Philippe, Verlant, Vincent, Poolman, Jan

“…Abstract In the past years, a significant rise in the proportion of childhood complicated pneumonia cases related to pneumococcal serotypes 1 and 3 has been…”
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Protective activity of the Bordetella pertussis BrkA autotransporter in the murine lung colonization model by Marr, Nico, Oliver, David C, Laurent, Vincianne, Poolman, Jan, Denoël, Philippe, Fernandez, Rachel C

“…Abstract This study examined the vaccine potential of the autotransporter protein BrkA of Bordetella pertussis in the sublethal intranasal murine respiratory…”
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Induction of Bordetella pertussis -specific immune memory by DTPa vaccines by Morel, Sandra, Denoël, Philippe, Godfroid, Fabrice, Cortvrindt, Caroline, Vanderheyde, Nathalie, Poolman, Jan

“…Abstract Several vaccines are available against pertussis, differing by the number of Bordetella pertussis antigens that they contain as well as their…”
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Global trends in antibiotic consumption during 2016–2023 and future projections through 2030 by Klein, Eili Y., Impalli, Isabella, Poleon, Suprena, Denoel, Philippe, Cipriano, Mariateresa, Van Boeckel, Thomas P., Pecetta, Simone, Bloom, David E., Nandi, Arindam

“…Antibiotic resistance is a global public health threat. Many factors contribute to this issue, with human antibiotic consumption being significant among them…”
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Passive immunization with human anti-protein D antibodies induced by polysaccharide protein D conjugates protects chinchillas against otitis media after intranasal challenge with Haemophilus influenzae by Novotny, Laura A., Jurcisek, Joseph A., Godfroid, Fabrice, Poolman, Jan T., Denoël, Philippe A., Bakaletz, Lauren O.

“…Passive transfer of a pediatric human serum pool generated against polysaccharide-protein D conjugate vaccines conferred ∼34% protection against development of…”
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Impact of the Innovative Medicines Initiative on vaccine development by Denoel, Philippe, Londoño-Hayes, Patricia, Chlebus, Magda, de Azero, Magdalena Rodriguez

“…Since its launch a decade ago, the European Innovative Medicines Initiative (IMI), a leading public–private partnership in life sciences, has catalysed…”
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Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium by Weiner, January, Lewis, David J. M., Maertzdorf, Jeroen, Mollenkopf, Hans-Joachim, Bodinham, Caroline, Pizzoferro, Kat, Linley, Catherine, Greenwood, Aldona, Mantovani, Alberto, Bottazzi, Barbara, Denoel, Philippe, Leroux-Roels, Geert, Kester, Kent E., Jonsdottir, Ingileif, van den Berg, Robert, Kaufmann, Stefan H. E., Del Giudice, Giuseppe

“…Biomarkers predictive of inflammatory events post-vaccination could accelerate vaccine development. Within the BIOVACSAFE framework, we conducted three…”
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