Search Results - "DeMayo, FJ"

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities by Lydon, J P, DeMayo, F J, Funk, C R, Mani, S K, Hughes, A R, Montgomery, Jr, C A, Shyamala, G, Conneely, O M, O'Malley, B W

“…Although progesterone has been recognized as essential for the establishment and maintenance of pregnancy, this steroid hormone has been recently implicated to…”
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Role of nuclear receptors in blastocyst implantation by Vasquez, Y.M., DeMayo, F.J.

“…•This review discusses the major nuclear receptors expressed in the endometrium during implantation and identifies important gaps that need to be addressed.•We…”
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Progesterone induction of calcitonin expression in the murine mammary gland by Ismail, PM, DeMayo, FJ, Amato, P, Lydon, JP

“…Progesterone, via its nuclear receptor, is mandatory not only for the induction and specification of mammary gland ductal side-branching and…”
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Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity by Tsai, Ming-Jer, Tsai, Sophia Y, You, Li-Ru, Lin, Fu-Jung, Lee, Christopher T, DeMayo, Francesco J

“…Arteries and veins are anatomically, functionally and molecularly distinct. The current model of arterial-venous identity proposes that binding of vascular…”
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p63 is the molecular switch for initiation of an epithelial stratification program by Koster, Maranke I, Kim, Soeun, Mills, Alea A, DeMayo, Francesco J, Roop, Dennis R

“…Development of stratified epithelia, such as the epidermis, requires p63 expression. The p63 gene encodes isoforms that contain (TA) or lack (DeltaN) a…”
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Animal models of implantation by Lee, Kevin Y, DeMayo, Francesco J

“…Implantation is an intricately timed event necessary in the process of viviparous birth that allows mammals to nourish and protect their young during early…”
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Defective in Mammary Gland Morphogenesis in Mice Lacking the Progesterone Receptor B Isoform by Mulac-Jericevic, Biserka, Lydon, John P., DeMayo, Francesco J., Conneely, Orla M.

“…Progesterone (P) regulates female reproduction via two nuclear receptors, PR-A and PR-B. Although both receptors display overlapping and distinct transcription…”
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β-catenin mediates glandular formation and dysregulation of β-catenin induces hyperplasia formation in the murine uterus by Jeong, J-W, Lee, H S, Franco, H L, Broaddus, R R, Taketo, M M, Tsai, S Y, Lydon, J P, DeMayo, F J

“…Endometrioid adenocarcinoma is the most frequent form of endometrial cancer, usually developing in pre- and peri-menopausal women. β-catenin abnormalities are…”
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Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus by DeMayo, Francesco J, Lee, Kevin, Jeong, JaeWook, Kwak, Inseok, Yu, Cheng-Tai, Lanske, Beate, Soegiarto, Desi W, Toftgard, Rune, Tsai, Ming-Jer, Tsai, Sophia, Lydon, John P

“…The hedgehog family of morphogens are regulators of cell proliferation, differentiation and cell-cell communication. These morphogens have been shown to have…”
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Cre-mediated recombination in cell lineages that express the progesterone receptor by Soyal, Selma M., Mukherjee, Atish, Lee, Kevin Y.-S., Li, Jie, Li, Huaiguang, DeMayo, Francesco J., Lydon, John P.

“…Using gene‐targeting methods, a progesterone receptor Cre knockin (PR‐Cre) mouse was generated in which Cre recombinase was inserted into exon 1 of the PR…”
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Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function by Yan, C, Wang, P, DeMayo, J, DeMayo, F J, Elvin, J A, Carino, C, Prasad, S V, Skinner, S S, Dunbar, B S, Dube, J L, Celeste, A J, Matzuk, M M

“…Knockout mouse technology has been used over the last decade to define the essential roles of ovarian-expressed genes and uncover genetic interactions. In…”
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Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility by Varani, Simona, Elvin, Julia A, Yan, Changning, DeMayo, Janet, DeMayo, Francesco J, Horton, Heidi F, Byrne, Michael C, Matzuk, Martin M

“…The ovulatory process is tightly regulated by endocrine as well as paracrine factors. In the periovulatory period, extensive remodeling of the follicle wall…”
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Roles of NPM2 in Chromatin and Nucleolar Organization in Oocytes and Embryos by Burns, Kathleen H., Viveiros, Maria M., Ren, Yongsheng, Wang, Pei, DeMayo, Francesco J., Frail, Donald E., Eppig, John J., Matzuk, Martin M.

“…Upon fertilization, remodeling of condensed maternal and paternal gamete DNA occurs to form the diploid genome. In Xenopus laevis, nucleoplasmin 2 (NPM2)…”
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Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform by Mulac-Jericevic, Biserka, Mullinax, Robert A., DeMayo, Francesco J., Lydon, John P., Conneely, Orla M.

“…Progesterone regulates reproductive function through two intracellular receptors, progesterone receptor-A (PR-A) and progesterone receptor-B (PR-B), that arise…”
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Mutation of the Androgen Receptor Causes Oncogenic Transformation of the Prostate by Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., Tilley, Wayne, Greenberg, Norman M., Allison, James P.

“…Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating…”
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Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy by Schneider, Michael D, Sano, Motoaki, Abdellatif, Maha, Oh, Hidemasa, Xie, Min, Bagella, Luigi, Giordano, Antonio, Michael, Lloyd H, DeMayo, Francesco J

“…Hypertrophic growth is a risk factor for mortality in heart diseases. Mechanisms are lacking for this global increase in RNA and protein per cell, which…”
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Mucin Is Produced by Clara Cells in the Proximal Airways of Antigen-Challenged Mice by Evans, Christopher M, Williams, Olatunji W, Tuvim, Michael J, Nigam, Rupesh, Mixides, George P, Blackburn, Michael R, DeMayo, Francesco J, Burns, Alan R, Smith, Charlotte, Reynolds, Susan D, Stripp, Barry R, Dickey, Burton F

“…Airway mucus hypersecretion is a prominent feature of many obstructive lung diseases. We thus determined the ontogeny and exocytic phenotype of mouse airway…”
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Mouse Lacking COUP-TFII as an Animal Model of Bochdalek-Type Congenital Diaphragmatic Hernia by Li-Ru You, Norio Takamoto, Cheng-Tai Yu, Tanaka, Toshiya, Kodama, Tatsuhiko, DeMayo, Francesco J., Tsai, Sophia Y., Tsai, Ming-Jer

“…Congenital diaphragmatic hernia (CDH), a life-threatening anomaly, is a major cause of pediatrie mortality. Although the disease was described >350 years ago,…”
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Identification of Murine Uterine Genes Regulated in a Ligand-Dependent Manner by the Progesterone Receptor by Jeong, Jae-Wook, Lee, Kevin Y, Kwak, Inseok, White, Lisa D, Hilsenbeck, Susan G, Lydon, John P, DeMayo, Francesco J

“…Progesterone (P4) acting through its cognate receptor, the progesterone receptor (PR), plays an important role in uterine physiology. The PR knockout (PRKO)…”
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Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor by SIVASUBRAMANIAN, Natarajan, COKER, Mytsi L, KURRELMEYER, Karla M, MACLELLAN, William R, DEMAYO, Francesco J, SPINALE, Francis G, MANN, Douglas L

“…The mechanisms responsible for tumor necrosis factor (TNF)-induced LV structural remodeling in the adult heart are not known. We generated a line of transgenic…”
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