Search Results - "DeMayo, F.J."

DNA binding and gene expression analysis of the progesterone receptor target FOS-like antigen 2 (FOSl2) in decidualizing human endometrial stromal cells by Mazur, E.C, Vasquez, Y.M, Kovanci, E, Gibbons, W.E, DeMayo, F.J

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Specific deletion of the progesterone receptor on CD11c dendritic cells reveals a progesterone-DC-crosstalk necessary to sustain fetal development by Thiele, K, Lydon, J.P, DeMayo, F.J, Arck, P.C

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Activator protein 1 (AP-1) members FOSL2 and JUN are direct targets of progesterone receptor and critical for human endometrial stroma cell decidualization by Mazur, E.C, Vasquez, Y.M, Kovanci, E, Jiang, L, Chen, R, DeMayo, F.J

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The transcriptional coactivator NCOA6 plays an essential role in the process of implantation through regulating the ERα expression and the sensitivity for E2 in uterus by Kawagoe, J, Li, Q, Liao, L, Lydon, J.P, DeMayo, F.J, Xu, J

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Molecular mechanisms involved in progesterone receptor regulation of uterine function by Lee, K., Jeong, J., Tsai, M.-J., Tsai, S., Lydon, J.P., DeMayo, F.J.

“…The ovarian steroid hormone progesterone is a major regulator of uterine function. The actions of this hormone is mediated through its cognate receptor, the…”
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Role of nuclear receptors in blastocyst implantation by Vasquez, Y.M., DeMayo, F.J.

“…•This review discusses the major nuclear receptors expressed in the endometrium during implantation and identifies important gaps that need to be addressed.•We…”
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Tissue-specific progesterone receptor-chromatin binding and the regulation of progesterone-dependent gene expression by Dinh, D. T., Breen, J., Akison, L. K., DeMayo, F. J., Brown, H. M., Robker, R. L., Russell, D. L.

“…Progesterone receptor (PGR) co-ordinately regulates ovulation, fertilisation and embryo implantation through tissue-specific actions, but the mechanisms for…”
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The promyelocytic leukemia Zinc finger transcription factor is required for human endometrial stromal cell decidualization by Szwarc, M.M., Lanz, R.B., Hai, L., Peavey, M.C., Gibbons, W.E., Kommagani, R., DeMayo, F.J., Lydon, J.P.

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β-catenin mediates glandular formation and dysregulation of β-catenin induces hyperplasia formation in the murine uterus by Jeong, J-W, Lee, H S, Franco, H L, Broaddus, R R, Taketo, M M, Tsai, S Y, Lydon, J P, DeMayo, F J

“…Endometrioid adenocarcinoma is the most frequent form of endometrial cancer, usually developing in pre- and peri-menopausal women. β-catenin abnormalities are…”
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Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis by Mao, J, DeMayo, F.J, Li, H, Abu-Elheiga, L, Gu, Z, Shaikenov, T.E, Kordari, P, Chirala, S.S, Heird, W.C, Wakil, S.J

“…In animals, liver and white adipose are the main sites for the de novo fatty acid synthesis. Deletion of fatty acid synthase or acetyl-CoA carboxylase (ACC) 1…”
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Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis by Lin, Y G, Shen, J, Yoo, E, Liu, R, Yen, H-Y, Mehta, A, Rajaei, A, Yang, W, Mhawech-Fauceglia, P, DeMayo, F J, Lydon, J, Gill, P, Lee, A S

“…Rates of the most common gynecologic cancer, endometrioid adenocarcinoma (EAC), continue to rise, mirroring the global epidemic of obesity, a well-known EAC…”
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Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment by Stodden, G R, Lindberg, M E, King, M L, Paquet, M, MacLean, J A, Mann, J L, DeMayo, F J, Lydon, J P, Hayashi, K

“…Type II endometrial carcinomas (ECs) are estrogen independent, poorly differentiated tumors that behave in an aggressive manner. As TP53 mutation and CDH1…”
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Ligand-inducible and liver-specific target gene expression in transgenic mice by WANG, Y, DEMAYO, F. J, TSAI, S. Y, O'MALLEY, B. W

“…Transgenic mice have been used as models for tissue-specific gene regulation and to examine the molecular and cellular effects of altered expression of…”
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SSTR5 ablation in islet results in alterations in glucose homeostasis in mice by Wang, X.P., Yang, J., Norman, M.A., Magnusson, J., DeMayo, F.J., Brunicardi, F.C.

“…Somatostatin (SST) peptide is a potent inhibitor of insulin secretion and its effect is mediated via somatostatin receptor 5 (SSTR5) in the endocrine pancreas…”
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Genetically engineered mouse models for lung cancer by Kwak, I, Tsai, S Y, DeMayo, F J

“…The lung is a complex organ consisting of numerous cell types that function to ensure sufficient gas exchange to oxygenate the blood. In order to accomplish…”
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Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5 by Reecy, J M, Li, X, Yamada, M, DeMayo, F J, Newman, C S, Harvey, R P, Schwartz, R J

“…Nkx2-5 marks the earliest recognizable cardiac progenitor cells, and is activated in response to inductive signals involved in lineage specification. Nkx2-5 is…”
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Alterations in glucose homeostasis in SSTR1 gene-ablated mice by Wang, X.P., Norman, M., Yang, J., Magnusson, J., Kreienkamp, H.-J., Richter, D., DeMayo, F.J., Brunicardi, F.C.

“…SSTR1 is found on the majority of human pancreatic beta cells, however, its role in insulin secretion has yet to be elucidated. In this study, we used the…”
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SSTR5 regulates pancreas gene expression and islet cell proliferation: A microarray analysis by Wang, X., Li, Z., Jeong, J., Liu, S., Magnusson, J., DeMayo, F.J., Brunicardi, F.

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The Effect of Global SSTR5 Gene Ablation on the Endocrine Pancreas and Glucose Regulation in Aging Mice1 by Wang, X.P., Norman, M., Yang, J., Liu, S.H., Magnusson, J., DeMayo, F.J., Brunicardi, F.C.

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Double-gene ablation of SSTR1 and SSTR5 results in hyperinsulinemia and improved glucose tolerance in mice by Wang, X.P., Norman, M.A., Yang, J., Cheung, A., Moldovan, S., DeMayo, F.J., Brunicardi, F.C.

“…Previous studies conducted in our laboratory showed that single-gene ablation of somatostatin receptor (SSTR)1 or 5 results in diabetes in mice. The objective…”
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