Search Results - "DeMaso, Catherine M."

Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males by Zellweger, Rene, Wichmann, Matthias W, Ayala, Alfred, Stein, Susan, DeMaso, Catherine M, Chaudry, Irshad H

“…OBJECTIVES To determinea) whether the cell-mediated immune response during sepsis differs in females vs. males; and b) whether the survival rate in females is…”
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ENHANCED IMMUNE RESPONSES IN FEMALES, AS OPPOSED TO DECREASED RESPONSES IN MALES FOLLOWING HAEMORRHAGIC SHOCK AND RESUSCITATION by Wichmann, Matthias W., Zellweger, René, DeMaso, Catherine M., Ayala, Alfred, Chaudry, Irshad H.

“…Although haemorrhagic shock produces immunodepression in both humans and experimental animals, no information is available concerning gender differences in the…”
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Mechanism of immunosuppression in males following trauma-hemorrhage. Critical role of testosterone by Wichmann, M W, Zellweger, R, DeMaso, C M, Ayala, A, Chaudry, I H

“…To determine whether male sex steroids contribute to the depression in cell-mediated immunity following trauma-hemorrhage and resuscitation. Two weeks before…”
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Immune function is more compromised after closed bone fracture and hemorrhagic shock than hemorrhage alone by Wichmann, M W, Zellweger, R, DeMaso, C M, Ayala, A, Williams, C, Chaudry, I H

“…To determine whether closed bone fracture in conjunction with hemorrhagic shock compromises immune functions more severely than hemorrhagic shock alone. In a…”
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Trauma-hemorrhage causes prolonged depression in cellular immunity by Zellweger, R, Ayala, A, DeMaso, C M, Chaudry, I H

“…A number of clinical studies have shown that multiple and severe trauma causes immunosuppression and increases the susceptibility to sepsis. However, because…”
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Prolactin administration following hemorrhagic shock improves macrophage cytokine release capacity and decreases mortality from subsequent sepsis by Zellweger, R, Zhu, XH, Wichmann, MW, Ayala, A, DeMaso, CM, Chaudry, IH

“…Although prolactin is reported to counteract the immunosuppressive effects of glucocorticoids, cyclosporine, and morphine, it remains unknown whether prolactin…”
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The induction of accelerated thymic programmed cell death during polymicrobial sepsis: control by corticosteroids but not tumor necrosis factor by Ayala, A, Herdon, C D, Lehman, D L, DeMaso, C M, Ayala, C A, Chaudry, I H

“…Thymic programmed cell death (PCD) or apoptosis (Ao) is elevated during inflammation by a variety of stressors in vitro (i.e., glucocorticoids, tumor necrosis…”
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Melatonin Administration Attenuates Depressed Immune Functions after Trauma-Hemorrhage by Wichmann, Matthias W., Zellweger, René, DeMaso, Catherine M., Ayala, Alfred, Chaudry, Irshad H.

“…The pineal hormone melatonin has been used in clinical trials in patients suffering from AIDS and also as an adjuvant for cancer therapy. Although melatonin…”
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Prolactin: A Novel and Safe Immunomodulating Hormone for the Treatment of Immunodepression Following Severe Hemorrhage by Zellweger, René, Wichmann, Matthias W., Ayala, Alfred, DeMaso, Catherine M., Chaudry, Irshad H.

“…Recent studies have shown that the anterior pituitary hormone prolactin, together with various cytokines, plays an important role in maintaining normal immune…”
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A Novel Nonanticoagulant Heparin Improves Splenocyte and Peritoneal Macrophage Immune Function after Trauma-Hemorrhage and Resuscitation by Zellweger, René, Ayala, Alfred, Zhu, Xiao-Lan, Holme, Kevin R., DeMaso, Catherine M., Chaudry, Irshad H.

“…Recent studies have shown that heparinization of animals prior to or even after hemorrhagic shock improves tissue perfusion and organ function. However, the…”
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Depressed Osteoblast Activity and Increased Osteocyte Necrosis after Closed Bone Fracture and Hemorrhagic Shock by Wichmann, Matthias W., Arnoczky, Steven P., DeMaso, Catherine M., Ayala, Alfred, Chaudry, Irshad H.

“…BACKGROUND Although bone fracture and hemorrhagic shock are frequent complications in trauma patients, it remains unknown whether hemorrhagic shock after bone…”
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