Search Results - "DeMaria, D D"

Unified mechanisms of Ca2+ regulation across the Ca2+ channel family by Liang, Haoya, DeMaria, Carla D, Erickson, Michael G, Mori, Masayuki X, Alseikhan, Badr A, Yue, David T

“…L-type (CaV1.2) and P/Q-type (CaV2.1) calcium channels possess lobe-specific CaM regulation, where Ca2+ binding to one or the other lobe of CaM triggers…”
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Calmodulin bifurcates the local Ca2+ signal that modulates P/Q-type Ca2+ channels by DeMaria, C D, Soong, T W, Alseikhan, B A, Alvania, R S, Yue, D T

“…Acute modulation of P/Q-type (alpha1A) calcium channels by neuronal activity-dependent changes in intracellular Ca2+ concentration may contribute to short-term…”
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Engineered Calmodulins Reveal the Unexpected Eminence of Ca2+Channel Inactivation in Controlling Heart Excitation by Alseikhan, Badr A., DeMaria, Carla D., Colecraft, Henry M., Yue, David T.

“…Engineered calmodulins (CaMs), rendered Ca2+-insensitive by mutations, function as dominant negatives in heterologous systems, and have revealed mechanisms of…”
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Using otolith morphometrics to quickly and inexpensively predict age in the gray angelfish ( Pomacanthus arcuatus) by Steward, Cheree A., DeMaria, Karen D., Shenker, Jonathan M.

“…We examined sagittal otoliths from 398 gray angelfish ( Pomacanthus arcuatus) collected from the lower Florida Keys between September 2000 and September 2003…”
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Alternative Splicing as a Molecular Switch for Ca2+/Calmodulin-Dependent Facilitation of P/Q-Type Ca2+ Channels by Chaudhuri, Dipayan, Chang, Siao-Yun, DeMaria, Carla D, Alvania, Rebecca S, Soong, Tuck Wah, Yue, David T

“…Alternative splicing of the P/Q-type channel (Ca(V)2.1) promises customization of the computational repertoire of neurons. Here we report that concerted…”
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Juveniles of the Caribbean’s largest coral reef snapper do not use reefs by Lindeman, K. C., DeMaria, D.

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N-Type Calcium Channel Inactivation Probed by Gating-Current Analysis by Jones, Lisa P., DeMaria, Carla D., Yue, David T.

“…N-type calcium channels inactivate most rapidly in response to moderate, not extreme depolarization. This behavior reflects an inactivation rate that bears a…”
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Ca2 Channel Modulation by Recombinant Auxiliary β Subunits Expressed in Young Adult Heart Cells by Wei, Shao-kui, Colecraft, Henry M, DeMaria, Carla D, Peterson, Blaise Z, Zhang, Rui, Kohout, Trudy A, Rogers, Terry B, Yue, David T

“…ABSTRACTL-type Ca channels contribute importantly to the normal excitation-contraction coupling of physiological hearts, and to the functional derangement seen…”
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Do pathogen-specific defense mechanisms contribute to wound-induced resistance in tomato? by Francia, D., Demaria, D., Calderini, O., Valentino, D., Ferraris, L., Arcioni, S., Tamietti, G., Cardinale, F.

“…A network of shared intermediates/components and/or common molecular outputs in biotic and abiotic stress signaling has long been known, but the possibility of…”
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A phase I clinical and pharmacokinetic study of the new topoisomerase inhibitor GI147211 given as a 72-h continuous infusion by PAZ-ARES, L, KUNKA, R, WISSEL, P, TWELVES, C, O'DWYER, P, DEMARIA, D, CASSIDY, J, ALDEN, M, BERANEK, P, KAYE, S, LITTLEFIELD, D, REILLY, D, DEPEE, S

“…GI147211 is a novel, totally synthetic camptothecin with promising preclinical and early clinical activity. This study was designed to determine the maximum…”
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Phase I/pharmacokinetic study of the topoisomerase I inhibitor GG211 administered as a 21-day continuous infusion by Stevenson, J. P., DeMaria, D., Sludden, J., Kaye, S. B., Paz-Ares, L., Grochow, L. B., McDonald, A., Selinger, K., Wissel, P., O'Dwyer, P. J., Twelves, C.

“…Background: Preclinical results support a prolonged schedule of administration for topoisomerase I inhibitors, and we have previously demonstrated the safety…”
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A phase I and pharmacokinetic study of tallimustine [PNU 152241 (FCE 24517)] in patients with advanced cancer by WEISS, G. R, POGGESI, I, O'DWYER, P, ROCCHETTI, M, DEMARIA, D, MOONEYHAM, T, REILLY, D, VITEK, L. V, WHALEY, F, PATRICIA, E, VON HOFF, D. D

“…Tallimustine [PNU 152241 (FCE 24517)] is a synthetic derivative of the DNA minor groove binder distamycin A, in which the NH2-terminal formyl group is…”
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Cross-protection mechanisms between biotic and abiotic stresses in plants by Demaria, D., Valentino, D., Matta, A., Cardinale, F.

“…In order to investigate cross-protection mechanisms between stresses of different origins, greenhouse experiments were conducted to determine whether…”
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Calmodulin is the Ca2+ sensor for Ca2+ -dependent inactivation of L-type calcium channels by Peterson, B Z, DeMaria, C D, Adelman, J P, Yue, D T

“…Elevated intracellular Ca2+ triggers inactivation of L-type calcium channels, providing negative Ca2+ feedback in many cells. Ca2+ binding to the main alpha1c…”
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Cancer battle gives clinical engineer new perspective on job, life by DeMaria, Dan

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Ca(2+) channel modulation by recombinant auxiliary beta subunits expressed in young adult heart cells by Wei, S K, Colecraft, H M, DeMaria, C D, Peterson, B Z, Zhang, R, Kohout, T A, Rogers, T B, Yue, D T

“…L-type Ca(2+) channels contribute importantly to the normal excitation-contraction coupling of physiological hearts, and to the functional derangement seen in…”
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Systematic Identification of Splice Variants in Human P/Q-Type Channel α12.1 Subunits: Implications for Current Density and Ca2+-Dependent Inactivation by Soong, Tuck Wah, DeMaria, Carla D., Alvania, Rebecca S., Zweifel, Larry S., Liang, Mui Cheng, Mittman, Scott, Agnew, William S., Yue, David T.

“…P/Q-type (Ca v 2.1) calcium channels support a host of Ca 2+ -driven neuronal functions in the mammalian brain. Alternative splicing of the main α 1A (α 1 2.1)…”
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Phase I trial of the thymidylate synthase inhibitor AG331 as a 5-day continuous infusion by O'DWYER, P. J, LAUB, P. B, GALLO, J. M, DEMARIA, D, QIAN, M, REILLY, D, GIANTONIO, B, JOHNSTON, A. L, WU, E. Y, BAUMAN, L, CLENDENINN, N. J

“…AG331 (N6-[4-(morpholinosulfonyl)benzyl]-N6-methyl-2, 6-diaminobenz-[c,d]-indole glucuronate) is a lipophilic thymidylate synthase inhibitor with activity in…”
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Phase I trial of etoposide, doxorubicin and cisplatin (EAP) in combination with GM-CSF by Ford, P.A., Arbuck, S.G., Minniti, C., Miller, L.L., Demaria, D., O'Dwyer, P.J.

“…The aim of this study was to ameliorate the toxicity of the etoposide, doxorubicin and cisplatin (EAP) regimen and to investigate the feasibility of dose…”
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Dynamics of sulfur dioxide absorption in excised porcine tracheae by Ben-Jebria, A, Full, A P, DeMaria, D D, Ball, B A, Ultman, J S

“…The absorption of sulfur dioxide (SO2) into excised porcine tracheae was characterized by a step-response experiment in which SO2 outlet concentration was…”
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