Search Results - "DeMarco, George J."
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Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor
Published in Nature communications (14-02-2018)“…Selective activation of dopamine D1 receptors (D1Rs) has been pursued for 40 years as a therapeutic strategy for neurologic and psychiatric diseases due to the…”
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Systems approach reveals photosensitivity and PER2 level as determinants of clock‐modulator efficacy
Published in Molecular systems biology (01-07-2019)“…In mammals, the master circadian clock synchronizes daily rhythms of physiology and behavior with the day–night cycle. Failure of synchrony, which increases…”
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Rodents Used for the Propagation of Hookworms and Haemonchus contortus
Published in Comparative medicine (01-08-2024)“…Helminthiasis due to hookworm infestations in humans and Haemonchus contortus in sheep cause untold levels of disease and economic losses worldwide. Drug…”
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A Review of the Effects of Pain and Analgesia on Immune System Function and Inflammation: Relevance for Preclinical Studies
Published in Comparative medicine (01-12-2019)“…One of the most significant challenges facing investigators, laboratory animal veterinarians, and IACUCs, is how to balance appropriate analgesic use, animal…”
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Rodents Used for the Propagation of Hookworms and Haemonchus contortus
Published in Comparative medicine (01-08-2024)“…Helminthiasis due to hookworm infestations in humans and Haemonchus contortus in sheep cause untold levels of disease and economic losses worldwide. Drug…”
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Journal Article -
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Differential cholinergic activation of G proteins in rat and mouse brainstem: Relevance for sleep and nociception
Published in Journal of comparative neurology (1911) (03-03-2003)“…Murine models are increasingly used for investigations of sleep, yet no previous studies have characterized cholinergic activation of guanine nucleotide…”
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Letter to the Editor
Published in Journal of the American Association for Laboratory Animal Science (01-01-2021)Get full text
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Letter to the Editor
Published in Journal of the American Association for Laboratory Animal Science (01-01-2021)Get full text
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Letter to the Editor
Published in Journal of the American Association for Laboratory Animal Science (01-01-2021)Get full text
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Pontine and basal forebrain cholinergic interaction: implications for sleep and breathing
Published in Respiratory physiology & neurobiology (15-11-2004)“…Pontine and forebrain cholinergic nuclei contribute to the regulation of breathing and arousal. This report summarizes experiments in rat ( n = 20) concerning…”
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Letters to the Editor
Published in Journal of the American Association for Laboratory Animal Science (01-03-2023)Get full text
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Systems approach reveals photosensitivity and PER 2 level as determinants of clock‐modulator efficacy
Published in Molecular systems biology (01-07-2019)“…In mammals, the master circadian clock synchronizes daily rhythms of physiology and behavior with the day–night cycle. Failure of synchrony, which increases…”
Get full text
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Letters to the Editor
Published in Journal of the American Association for Laboratory Animal Science (01-03-2023)Get full text
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Letters to the Editor
Published in Journal of the American Association for Laboratory Animal Science (01-03-2023)Get full text
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Increased dendrite branching in AbetaPP/PS1 mice and elongation of dendrite arbors by fasudil administration
Published in Journal of Alzheimer's disease (2010)“…Amyloid-beta (Abeta) overproduction and dendrite arbor atrophy are hallmarks of Alzheimer's disease. The RhoA GTPase (Rho) signals through Rho kinase (ROCK) to…”
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Central Modulation of Circadian Rhythm via CK1 Inhibition for Psychiatric Indications
Published in Annual Reports in Medicinal Chemistry (2011)Get full text
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Microsomal nicotine metabolism: a comparison of relative activities of six purified rabbit cytochrome P-450 isozymes
Published in Biochemical pharmacology (01-04-1989)Get more information
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Characterization of hamster liver nicotine metabolism. I. Relative rates of microsomal C and N oxidation
Published in Biochemical pharmacology (15-08-1986)“…A high pressure liquid chromatographic procedure has been developed for the determination of the two principal N- and C-oxidation products of nicotine in…”
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