Search Results - "DeLucia, Michael W."

Single-dose intracerebroventricular administration of galactocerebrosidase improves survival in a mouse model of globoid cell leukodystrophy by Lee, Wing C, Tsoi, Yuen K, Troendle, Frederick J, DeLucia, Michael W, Ahmed, Zeshan, Dicky, Chad A, Dickson, Dennis W, Eckman, Christopher B

“…Globoid cell leukodystrophy (GLD), also known as Krabbe disease, is a devastating, degenerative neurological disorder. It is inherited as an autosomal…”
Get full text

Enzyme replacement therapy results in substantial improvements in early clinical phenotype in a mouse model of globoid cell leukodystrophy by Lee, Wing C, Courtenay, Andrew, Troendle, Frederick J, Stallings-Mann, Melody L, Dickey, Chad A, DeLucia, Michael W, Dickson, Dennis W, Eckman, Christopher B

“…ABSTRACTGloboid cell leukodystrophy (GLD) or Krabbe disease is a devastating, degenerative neurological disorder caused by mutations in the…”
Get full text

Alzheimer Disease With Amygdala Lewy Bodies: A Distinct Form of α-Synucleinopathy by Uchikado, Hirotake, Lin, Wen-Lang, DeLucia, Michael W, Dickson, Dennis W

“…Lewy bodies (LBs) are α-synuclein-immunoreactive neuronal inclusions with a predilection for specific cortical and subcortical regions, including the amygdala…”
Get full text

Suppression of galactosylceramidase (GALC) expression in the twitcher mouse model of globoid cell leukodystrophy (GLD) is caused by nonsense-mediated mRNA decay (NMD) by Lee, Wing C., Tsoi, Yuen K., Dickey, Chad A., DeLucia, Michael W., Dickson, Dennis W., Eckman, Christopher B.

“…The twitcher mouse is a pathologically and enzymatically authentic model of globoid cell leukodystrophy (GLD, Krabbe disease) that has been widely used for the…”
Get full text

Hereditary diffuse leukoencephalopathy with spheroids: clinical, pathologic and genetic studies of a new kindred by Baba, Yasuhiko, Ghetti, Bernardino, Baker, Matthew C, Uitti, Ryan J, Hutton, Michael L, Yamaguchi, Keiji, Bird, Thomas, Lin, Wenlang, DeLucia, Michael W, Dickson, Dennis W, Wszolek, Zbigniew K

“…Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is a rare autosomal dominant disorder characterized by cerebral white matter degeneration with…”
Get full text

α-Synuclein immunoreactivity in neuronal nuclear inclusions and neurites in multiple system atrophy by Lin, Wen-Lang, DeLucia, Michael W., Dickson, Dennis W.

“…We examined neuronal and oligodendroglial nuclear inclusions and neurites in the pontine base of multiple system atrophy brains using an antibody to…”
Get full text

Argyrophilic Grain Disease in Demented Subjects Presenting Initially With Amnestic Mild Cognitive Impairment by Jicha, Gregory A, Petersen, Ronald C, Knopman, David S, Boeve, Bradley F, Smith, Glenn E, Geda, Yonas E, Johnson, Kris A, Cha, Ruth, DeLucia, Michael W, Braak, Heiko, Dickson, Dennis W, Parisi, Joseph E

“…A previous autopsy study of patients with amnestic-type mild cognitive impairment (MCI) suggested an overrepresentation of argyrophilic grain disease (AGD). We…”
Get full text

Alzheimer Disease With Amygdala Lewy Bodies: A Distinct Form of [alpha]-Synucleinopathy by Uchikado, Hirotake, Wen-Lang, Lin, DeLucia, Michael W, Dickson, Dennis W

“…Lewy bodies (LBs) are alpha-synuclein-immunoreactive neuronal inclusions with a predilection for specific cortical and subcortical regions, including the…”
Get full text