Search Results - "DeLucia, Diana C."

B Lymphocytes, but Not Dendritic Cells, Efficiently HIV-1 Trans Infect Naive CD4 + T Cells: Implications for the Viral Reservoir by Gerberick, Abigail, DeLucia, Diana C, Piazza, Paolo, Alaoui-El-Azher, Mounia, Rinaldo, Charles R, Sluis-Cremer, Nicolas, Rappocciolo, Giovanna

“…Insight into the establishment and maintenance of HIV-1 infection in resting CD4 T cell subsets is critical for the development of therapeutics targeting the…”
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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis by Chour, William, Choi, Jongchan, Xie, Jingyi, Chaffee, Mary E., Schmitt, Thomas M., Finton, Kathryn, DeLucia, Diana C., Xu, Alexander M., Su, Yapeng, Chen, Daniel G., Zhang, Rongyu, Yuan, Dan, Hong, Sunga, Ng, Alphonsus H. C., Butler, Jonah Z., Edmark, Rick A., Jones, Lesley C., Murray, Kim M., Peng, Songming, Li, Guideng, Strong, Roland K., Lee, John K., Goldman, Jason D., Greenberg, Philip D., Heath, James R.

“…The discovery and characterization of antigen-specific CD8 + T cell clonotypes typically involves the labor-intensive synthesis and construction of peptide-MHC…”
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Inefficient HIV-1 trans infection of CD4 + T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN by DeLucia, Diana C, Rinaldo, Charles R, Rappocciolo, Giovanna

“…Professional antigen presenting cells (APC: myeloid dendritic cells (DC) and macrophages (MΦ); B lymphocytes) mediate highly efficient HIV-1 infection of CD4 T…”
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Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5-SN38 Antibody-drug Conjugate in Neuroendocrine Prostate Cancer by DeLucia, Diana C, Cardillo, Thomas M, Ang, Lisa, Labrecque, Mark P, Zhang, Ailin, Hopkins, James E, De Sarkar, Navonil, Coleman, Ilsa, da Costa, Rui M Gil, Corey, Eva, True, Lawrence D, Haffner, Michael C, Schweizer, Michael T, Morrissey, Colm, Nelson, Peter S, Lee, John K

“…Neuroendocrine prostate cancer (NEPC) is an aggressive form of castration-resistant prostate cancer (CRPC) for which effective therapies are lacking. We…”
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Identification of Cell Surface Targets for CAR T Cell Immunotherapy by DeLucia, Diana C, Lee, John K

“…Immunotherapy has become a prominent approach for the treatment of cancer. Targeted killing of malignant cells by adoptive transfer of chimeric antigen…”
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Development of Cancer Immunotherapies by DeLucia, Diana C, Lee, John K

“…Cancer immunotherapy, or the utilization of components of the immune system to target and eliminate cancer, has become a highly active area of research in the…”
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Human Herpesvirus 8 Infects and Replicates in Langerhans Cells and Interstitial Dermal Dendritic Cells and Impairs Their Function by Rappocciolo, Giovanna, Jais, Mariel, Piazza, Paolo A, DeLucia, Diana C, Jenkins, Frank J, Rinaldo, Charles R

“…The predominant types of dendritic cells (DC) in the skin and mucosa are Langerhans cells (LC) and interstitial dermal DC (iDDC). LC and iDDC process cutaneous…”
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Targeting the fibroblast growth factor pathway in molecular subtypes of castration‐resistant prostate cancer by Labrecque, Mark P., Brown, Lisha G., Coleman, Ilsa M., Nguyen, Holly M., Dalrymple, Susan, Brennen, W. Nathaniel, Isaacs, John T., Li, Dapei, Lakely, Bryce, DeLucia, Diana C., Lee, John K., Schweizer, Michael T., Lin, Daniel W., Corey, Eva, Nelson, Peter S., Morrissey, Colm

“…Background Androgen receptor (AR) pathway inhibition remains the cornerstone for prostate cancer therapies. However, castration‐resistant prostate cancer…”
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Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation by Mao, Zhiyuan, Nesterenko, Pavlo A., McLaughlin, Jami, Deng, Weixian, Burton Sojo, Giselle, Cheng, Donghui, Noguchi, Miyako, Chour, William, DeLucia, Diana C., Finton, Kathryn A., Qin, Yu, Obusan, Matthew B., Tran, Wendy, Wang, Liang, Bangayan, Nathanael J., Ta, Lisa, Chen, Chia-Chun, Seet, Christopher S., Crooks, Gay M., Phillips, John W., Heath, James R., Strong, Roland K., Lee, John K., Wohlschlegel, James A., Witte, Owen N.

“…Tissue-specific antigens can serve as targets for adoptive T cell transfer-based cancer immunotherapy. Recognition of tumor by T cells is mediated by…”
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Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities by Xu, Alexander M, Chour, William, DeLucia, Diana C, Su, Yapeng, Pavlovitch-Bedzyk, Ana Jimena, Ng, Rachel, Rasheed, Yusuf, Davis, Mark M, Lee, John K, Heath, James R

“…Antigen-specific T cell receptor (TCR) sequences can have prognostic, predictive, and therapeutic value, but decoding the specificity of TCR recognition…”
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Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers by Zhang, Ailin, Lau, Nathan A, Wong, Alicia, Brown, Lisha G, Coleman, Ilsa M, De Sarkar, Navonil, Li, Dapei, DeLucia, Diana C, Labrecque, Mark P, Nguyen, Holly M, Conner, Jennifer L, Dumpit, Ruth F, True, Lawrence D, Lin, Daniel W, Corey, Eva, Alumkal, Joshi J, Nelson, Peter S, Morrissey, Colm, Lee, John K

“…Castration-resistant prostate cancer (CRPC) consists of multiple phenotypic subtypes including androgen receptor (AR)-active prostate cancer (ARPC) and…”
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Cellular Cholesterol Regulation of HIV-1 Trafficking During Macrophage-Mediated Trans Infection by DeLucia, Diana C

“…Professional antigen presenting cells (APC: myeloid dendritic cells (DC) and macrophages (MΦ); B lymphocytes) mediate highly efficient HIV-1 infection of CD4+…”
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