Search Results - "DeLong, Jonathan"
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Role of Inflammatory Processes in Hemorrhagic Stroke
Published in Stroke (1970) (01-02-2023)“…Hemorrhagic stroke is the deadliest form of stroke and includes the subtypes of intracerebral hemorrhage and subarachnoid hemorrhage. A common cause of…”
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Specific immunotherapy modifies allergen-specific CD4+ T-cell responses in an epitope-dependent manner
Published in Journal of allergy and clinical immunology (01-03-2014)“…Background Understanding the mechanisms by which the immune system induces and controls allergic inflammation at the T-cell epitope level is critical for the…”
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Divergent Functions of Tissue-Resident and Blood-Derived Macrophages in the Hemorrhagic Brain
Published in Stroke (1970) (01-05-2021)“…Brain tissue-resident microglia and monocyte-derived macrophages (MDMs) are innate immune cells that contribute to the inflammatory response, phagocytosis of…”
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Current status and future perspectives of fluorescence-guided surgery for cancer
Published in Expert review of anticancer therapy (02-01-2016)“…Curative cancer surgery is dependent on the removal of all primary tumor and metastatic cancer cells. Preoperative imaging, intraoperative inspection and…”
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Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy
Published in Journal of allergy and clinical immunology (01-02-2012)“…Background The main obstacle to elucidating the role of CD4+ T cells in allergen-specific immunotherapy (SIT) has been the absence of an adequately sensitive…”
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T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1
Published in Nature immunology (01-12-2013)“…Hematopoietic deficiency in the Notch target Hes1 results in severe defects in the T cell lineage. Bhandoola and colleagues show that Hes1 constrains myeloid…”
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PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection
Published in Nature immunology (01-05-2022)“…Phenotypic and transcriptional profiling of regulatory T (T reg ) cells at homeostasis reveals that T cell receptor activation promotes T reg cells with an…”
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Indocyanine green fluorescence-guided parathyroidectomy for primary hyperparathyroidism
Published in Surgery (01-02-2018)“…Our aim was to evaluate the ease and utility of using indocyanine green fluorescence angiography for intraoperative localization of the parathyroid glands…”
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Solving the surgeon ergonomic crisis with surgical exosuit
Published in Surgical endoscopy (2018)“…Introduction The widespread adoption of laparoscopic surgery has put new physical demands on the surgeon leading to increased musculoskeletal disorders and…”
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Ara h 1–reactive T cells in individuals with peanut allergy
Published in Journal of allergy and clinical immunology (01-05-2011)“…Background Effective immunotherapy for peanut allergy is hampered by a lack of understanding of peanut-reactive CD4+ T cells. Objective To identify,…”
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Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1
Published in The Journal of immunology (1950) (01-03-2018)“…Ly6C and Sca-1 (Ly6A/E) are Ly6 family GPI-anchored surface molecules that are differentially expressed by multiple immune populations. Ly6C expression has…”
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Loss of IL-27Rα Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses
Published in The Journal of immunology (1950) (15-07-2020)“…Clinical and experimental studies have established that immune cells such as alternatively activated (M2) macrophages and Th17 cells play a role in the…”
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Upcoming multi-visceral robotic surgery systems: a SAGES review
Published in Surgical endoscopy (14-11-2024)“…Robotic surgical procedures continue to increase both in the United States (US) and worldwide. Several novel robotic surgical platforms are under development…”
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Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system
Published in Nature microbiology (15-02-2016)“…An important function of the blood–brain barrier is to exclude pathogens from the central nervous system, but some microorganisms benefit from the ability to…”
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Near-infrared–conjugated humanized anti-carcinoembryonic antigen antibody targets colon cancer in an orthotopic nude mouse model
Published in The Journal of surgical research (01-10-2017)“…Abstract Background The success of a curative surgery for cancer is dependent on the complete removal of all cancer cells. Tumor visualization by the surgeon…”
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IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection
Published in PLoS pathogens (01-01-2017)“…Respiratory paramyxoviruses are important causes of morbidity and mortality, particularly of infants and the elderly. In humans, a T helper (Th)2-biased immune…”
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Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model
Published in Oncotarget (30-05-2017)“…Methionine dependence is due to the overuse of methionine for aberrant transmethylation reactions in cancer. Methionine dependence may be the only general…”
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Postoperative outcomes and costs of laparoscopic versus robotic distal pancreatectomy: a propensity-matched analysis
Published in Surgical endoscopy (01-04-2024)“…Background Minimally invasive distal pancreatectomy (MIDP) has established advantages over the open approach. The costs associated with robotic DP (RDP) versus…”
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Indocyanine green (ICG) fluorescence-guided laparoscopic adrenalectomy
Published in Journal of surgical oncology (01-11-2015)“…Objective Laparoscopic adrenalectomy has become the standard of care for many adrenal tumors. However, the success of the operation hinges on identifying the…”
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Impact of Interleukin-27p28 on T and B Cell Responses during Toxoplasmosis
Published in Infection and immunity (01-12-2019)“…Interleukin-27 (IL-27) is a heterodimeric cytokine composed of the subunits IL-27p28 and EBi3, and while the IL-27 heterodimer influences T cell activities,…”
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