Search Results - "DeLisle, D M"
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Structure-Assisted Design of Mechanism-Based Irreversible Inhibitors of Human Rhinovirus 3C Protease with Potent Antiviral Activity against Multiple Rhinovirus Serotypes
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-1999)“…Human rhinoviruses, the most important etiologic agents of the common cold, are messenger-active single-stranded monocistronic RNA viruses that have evolved a…”
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Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease
Published in Journal of medicinal chemistry (20-12-1996)“…The design, synthesis, and biological evaluation of reversible, nonpeptidic inhibitors of human rhinovirus (HRV) 3C protease (3CP) are reported. A novel series…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies
Published in Journal of medicinal chemistry (16-07-1998)“…The structure-based design, chemical synthesis, and biological evaluation of peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are described…”
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4
The respiratory burst oxidase of human neutrophils. Further studies of the purified enzyme
Published in The Journal of biological chemistry (05-10-1986)“…A superoxide-forming oxidase from activated human neutrophil membranes was solubilized by two slightly different methods, then purified by "dye-affinity"…”
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A microtechnique for neutrophil respiratory burst oxidase in a cell-free system--characterization of oxidase activation system
Published in Comparative biochemistry and physiology. B, Comparative biochemistry (1990)“…1. A microtechnique for quantitating human neutrophil NADPH oxidase in a cell-free system is described. 2. This spectrophotometric discontinuous (fixed time)…”
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Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease: Structure-Based Design, Synthesis, and Biological Evaluation
Published in Journal of medicinal chemistry (04-05-2000)“…A series of nonpeptide benzamide-containing inhibitors of human rhinovirus (HRV) 3C protease was identified using structure-based design. The design,…”
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Interaction of a Novel GDP Exchange Inhibitor with the Ras Protein
Published in Biochemistry (Easton) (10-11-1998)“…Mutated, tumorigenic Ras is present in a variety of human tumors. Compounds that inhibit tumorigenic Ras function may be useful in the treatment of Ras-related…”
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A Breast Reduction Technique for the Free DIEP Flap Post Breast Reconstruction
Published in Plastic and reconstructive surgery. Global open (01-08-2024)“…Breast flap remodeling is a common procedure after breast reconstruction. We present a unique approach to breast reduction using a superomedial pedicle…”
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A case of relapsed systemic multiple myeloma mimicking adenopathy and extensive skin patch overlying a plasmacytoma
Published in JAAD Case Reports (01-07-2022)Get full text
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Refusal of colorectal cancer surgery in the United States: Predictors and associated cancer-specific mortality in a Surveillance, Epidemiology, and End Results (SEER) cohort
Published in Surgery open science (01-10-2020)“…This study aims to understand patient factors associated with refusal of surgery for nonmetastatic colorectal cancer and the associated cancer-specific…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies
Published in Journal of medicinal chemistry (16-07-1998)“…The structure-based design, chemical synthesis, and biological evaluation of various peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are…”
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12
Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial
Published in The Lancet (British edition) (20-12-2008)“…Summary Background One course of antenatal corticosteroids reduces the risk of respiratory distress syndrome and neonatal death. Weekly doses given to women…”
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Cervical Insufficiency and Cervical Cerclage
Published in Journal of obstetrics and gynaecology Canada (01-12-2013)“…Abstract Objective The purpose of this guideline is to provide a framework that clinicians can use to determine which women are at greatest risk of having…”
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Incidence, Timing, and Predictive Factors of New-Onset Migraine Headache Attack After Transcatheter Closure of Atrial Septal Defect or Patent Foramen Ovale
Published in The American journal of cardiology (01-03-2008)“…The objectives of this study were to evaluate the incidence, predictive factors, and duration of migraine headache attack (MHA) after transcatheter atrial…”
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Obesity in Pregnancy
Published in Journal of obstetrics and gynaecology Canada (01-02-2010)“…Abstract Objective To review the evidence and provide recommendations for the counselling and management of obese parturients. Outcomes Outcomes evaluated…”
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Fetal Outcomes of Prenatally Diagnosed Congenital Diaphragmatic Hernia: Nine Years of Clinical Experience in a Canadian Tertiary Hospital
Published in Journal of obstetrics and gynaecology Canada (2016)“…Abstract Objective To summarize the clinical outcome of congenital diaphragmatic hernia (CDH) identified on prenatal ultrasound. Method We reviewed prenatally…”
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Using Cost-Effectiveness Analysis to Sharpen Formulary Decision-Making: The Example of Tiotropium at the Veterans Affairs Health Care System
Published in Value in health (01-09-2008)“…Abstract Objective To identify a cost-saving subset of criteria for the use of tiotropium at a Veterans Affairs Medical Center based on a cost-effectiveness…”
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Galectin-1 is a powerful marker to distinguish chondroblastic osteosarcoma and conventional chondrosarcoma
Published in Human pathology (01-09-2010)“…Summary The clinical management of osteosarcoma differs significantly from that of chondrosarcoma; therefore, it is extremely important to diagnose these 2…”
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In Response
Published in Journal of obstetrics and gynaecology Canada (2014)Get full text
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The β 5/focal adhesion kinase/glycogen synthase kinase 3 β integrin pathway in high-grade osteosarcoma: a protein expression profile predictive of response to neoadjuvant chemotherapy
Published in Human pathology (01-10-2013)“…Summary To date, chemosensitivity to neoadjuvant chemotherapy of patients with high-grade osteosarcoma is evaluated on surgical resection by evaluation of the…”
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