Search Results - "DeLano, Travis J."

Enantioselective Electroreductive Coupling of Alkenyl and Benzyl Halides via Nickel Catalysis by DeLano, Travis J, Reisman, Sarah E

“…An electrochemically driven enantioselective nickel-catalyzed reductive cross-coupling of alkenyl bromides and benzyl chlorides is reported. The reaction forms…”
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Multilabel Classification Models for the Prediction of Cross-Coupling Reaction Conditions by Maser, Michael R, Cui, Alexander Y, Ryou, Serim, DeLano, Travis J, Yue, Yisong

“…Machine-learned ranking models have been developed for the prediction of substrate-specific cross-coupling reaction conditions. Data sets of published…”
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Ni-Catalyzed Asymmetric Reductive Arylation of α‑Substituted Imides by Chen, Li-Ming, Shin, Chungkeun, DeLano, Travis J., Carretero-Cerdán, Alba, Gheibi, Golsa, Reisman, Sarah E.

“…α-Aryl imides are common structural motifs in bioactive molecules and proteolysis-targeting chimeras designed for targeted protein degradation. An asymmetric…”
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Enantioselective Synthesis of N‑Benzylic Heterocycles by Ni/Photoredox Dual Catalysis by Lacker, Caitlin R., DeLano, Travis J., Chen, Emily P., Kong, Jongrock, Belyk, Kevin M., Piou, Tiffany, Reisman, Sarah E.

“…An asymmetric cross-coupling of α-N-heterocyclic trifluoroborates with aryl bromides using Ni/photoredox dual catalysis has been developed. This…”
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Nickel-catalyzed asymmetric reductive cross-coupling of α-chloroesters with (hetero)aryl iodides by DeLano, Travis J, Dibrell, Sara E, Lacker, Caitlin R, Pancoast, Adam R, Poremba, Kelsey E, Cleary, Leah, Sigman, Matthew S, Reisman, Sarah E

“…An asymmetric reductive cross-coupling of α-chloroesters and (hetero)aryl iodides is reported. This nickel-catalyzed reaction proceeds with a chiral BiOX…”
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Application of the Photoredox Coupling of Trifluoroborates and Aryl Bromides to Analog Generation Using Continuous Flow by DeLano, Travis J, Bandarage, Upul K, Palaychuk, Natalie, Green, Jeremy, Boyd, Michael J

“…A method for the coupling of aryl bromides with potassium alkyl trifluoroborates, via nickel/photoredox dual catalysis, has been developed for use in…”
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Synthesis of Cycloalkyl Substituted 7‑Azaindoles via Photoredox Nickel Dual Catalytic Cross-Coupling in Batch and Continuous Flow by Palaychuk, Natalie, DeLano, Travis J, Boyd, Michael J, Green, Jeremy, Bandarage, Upul K

“…An efficient photoredox/Ni dual catalytic Csp2 –Csp3 cross-coupling protocol in a continuous-flow regime to synthesize a variety of regioisomeric cycloalkyl…”
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Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum by Absalon, Sabrina, Blomqvist, Karin, Rudlaff, Rachel M, DeLano, Travis J, Pollastri, Michael P, Dvorin, Jeffrey D

“…The human malaria parasite requires efficient egress out of an infected red blood cell for pathogenesis. This egress event is highly coordinated and is…”
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Structure-property studies of an imidazoquinoline chemotype with antitrypanosomal activity by Klug, Dana M, Diaz-Gonzalez, Rosario, DeLano, Travis J, Mavrogiannaki, Eftychia M, Buskes, Melissa J, Dalton, Raeann M, Fisher, John K, Schneider, Katherine M, Hilborne, Vivian, Fritsche, Melanie G, Simpson, Quillon J, Tear, Westley F, Devine, William G, Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, García-Hernández, Raquel, Bosch-Navarrete, Cristina, Ruiz-Pérez, Luis Miguel, Gamarro, Francisco, González-Pacanowska, Dolores, Martinez-Martinez, Maria Santos, Manzano-Chinchon, Pilar, Navarro, Miguel, Pollastri, Michael P, Ferrins, Lori

“…Human African trypanosomiasis is a neglected tropical disease (NTD) that is fatal if left untreated. Although approximately 13 million people live in moderate-…”
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Ni-Catalyzed Asymmetric Reductive Arylation of α-Substituted Imides by Chen, Li-Ming, Shin, Chungkeun, Delano, Travis J., Carretero-Cerdan, Alba, Gheibi, Golsa, Reisman, Sarah E.

“…alpha-Aryl imides are common structural motifs in bioactive molecules and proteolysis-targeting chimeras designed for targeted protein degradation. An…”
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Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in italic toggle="yes">Plasmodium falciparum /italic by Sabrina Absalon, Karin Blomqvist, Rachel M. Rudlaff, Travis J. DeLano, Michael P. Pollastri, Jeffrey D. Dvorin

“…ABSTRACT The human malaria parasite Plasmodium falciparum requires efficient egress out of an infected red blood cell for pathogenesis. This egress event is…”
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Structure–property studies of an imidazoquinoline chemotype with antitrypanosomal activity† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0md00103a by Klug, Dana M., Diaz-Gonzalez, Rosario, DeLano, Travis J., Mavrogiannaki, Eftychia M., Buskes, Melissa J., Dalton, Raeann M., Fisher, John K., Schneider, Katherine M., Hilborne, Vivian, Fritsche, Melanie G., Simpson, Quillon J., Tear, Westley F., Devine, William G., Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, García-Hernández, Raquel, Bosch-Navarrete, Cristina, Ruiz-Pérez, Luis Miguel, Gamarro, Francisco, González-Pacanowska, Dolores, Martinez-Martinez, Maria Santos, Manzano-Chinchon, Pilar, Navarro, Miguel, Pollastri, Michael P., Ferrins, Lori

“…Structure–property and structure–activity studies identify regions that positively modulate aqueous solubility; though maintaining potent anti-trypanosomal…”
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Graph Neural Networks for the Prediction of Substrate-Specific Organic Reaction Conditions by Ryou, Serim, Maser, Michael R, Cui, Alexander Y, DeLano, Travis J, Yue, Yisong, Reisman, Sarah E

“…We present a systematic investigation using graph neural networks (GNNs) to model organic chemical reactions. To do so, we prepared a dataset collection of…”
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