Search Results - "DeKoter, Rodney P"

Peyer's Patch M Cells Derived from Lgr5+ Stem Cells Require SpiB and Are Induced by RankL in Cultured “Miniguts” by de Lau, Wim, Kujala, Pekka, Schneeberger, Kerstin, Middendorp, Sabine, Li, Vivian S. W., Barker, Nick, Martens, Anton, Hofhuis, Frans, DeKoter, Rodney P., Peters, Peter J., Nieuwenhuis, Edward, Clevers, Hans

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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PU.1 Regulates Ig Light Chain Transcription and Rearrangement in Pre-B Cells during B Cell Development by Batista, Carolina R, Li, Stephen K H, Xu, Li S, Solomon, Lauren A, DeKoter, Rodney P

“…B cell development and Ig rearrangement are governed by cell type- and developmental stage-specific transcription factors. PU.1 and Spi-B are…”
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The Transcription Factor PU.1 is a Critical Regulator of Cellular Communication in the Immune System by Turkistany, Shereen A., DeKoter, Rodney P.

“…PU.1 is an E26 transformation-specific family transcription factor that is required for development of the immune system. PU.1 functions at both early and late…”
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Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c by Camargo, Fernando D, Stehling-Sun, Sandra, Dade, Jessica, Nutt, Stephen L, DeKoter, Rodney P

“…Myeloid and lymphoid cells are derived from the same multipotent progenitor cell. Camargo and colleagues show that the transcription factor Mef2c restricts…”
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Regulation of B Lymphocyte and Macrophage Development by Graded Expression of PU.1 by DeKoter, Rodney P., Singh, Harinder

“…The ets family transcription factor PU.1 is required for the development of multiple lineages of the immune system. Using retroviral transduction of PU. 1…”
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Genome-wide comparison of PU.1 and Spi-B binding sites in a mouse B lymphoma cell line by Solomon, Lauren A, Li, Stephen K H, Piskorz, Jan, Xu, Li S, DeKoter, Rodney P

“…Spi-B and PU.1 are highly related members of the E26-transformation-specific (ETS) family of transcription factors that have similar, but not identical, roles…”
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PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors by DeKoter, Rodney P., Lee, Hyun-Jun, Singh, Harinder

“…Development of the lymphoid system is dependent on the Ets family transcription factor PU.1. We demonstrate that PU.1 −/− hematopoietic progenitors fail to…”
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Identification of a negative regulatory role for spi-C in the murine B cell lineage by Li, Stephen K H, Solomon, Lauren A, Fulkerson, Patricia C, DeKoter, Rodney P

“…Spi-C is an E26 transformation-specific family transcription factor that is highly related to PU.1 and Spi-B. Spi-C is expressed in developing B cells, but its…”
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Deletion of genes encoding PU.1 and Spi-B in B cells impairs differentiation and induces pre-B cell acute lymphoblastic leukemia by Sokalski, Kristen M., Li, Stephen K.H., Welch, Ian, Cadieux-Pitre, Heather-Anne T., Gruca, Marek R., DeKoter, Rodney P.

“…The E26 transformation-specific (Ets) transcription factor PU.1 is required to generate lymphoid progenitor cells from hematopoietic stem cells, but it is not…”
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Regulation of B cell linker protein transcription by PU.1 and Spi-B in murine B cell acute lymphoblastic leukemia by Xu, Li S, Sokalski, Kristen M, Hotke, Kathryn, Christie, Darah A, Zarnett, Oren, Piskorz, Jan, Thillainadesan, Gobi, Torchia, Joseph, DeKoter, Rodney P

“…B cell acute lymphoblastic leukemia (B-ALL) is frequently associated with mutations or chromosomal translocations of genes encoding transcription factors…”
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Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C by DeKoter, Rodney P, Geadah, Marc, Khoosal, Sonam, Xu, Li S, Thillainadesan, Gobi, Torchia, Joseph, Chin, Shu Shien, Garrett-Sinha, Lee Ann

“…Splenic B-2 cells can be divided into two major subsets: follicular (FO) and marginal zone (MZ) B cells. FO and MZ B cells are generated from immature…”
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Driver mutations in Janus kinases in a mouse model of B-cell leukemia induced by deletion of PU.1 and Spi-B by Batista, Carolina R., Lim, Michelle, Laramée, Anne-Sophie, Abu-Sardanah, Faisal, Xu, Li S., Hossain, Rajon, Bell, Gillian I., Hess, David A., DeKoter, Rodney P.

“…Precursor B-cell acute lymphoblastic leukemia (B-ALL) is associated with recurrent mutations that occur in cancer-initiating cells. There is a need to…”
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Cooperative and Antagonistic Interplay between PU.1 and GATA-2 in the Specification of Myeloid Cell Fates by Walsh, Jonathan C., DeKoter, Rodney P., Lee, Hyun-Jun, Smith, Erica D., Lancki, David W., Gurish, Michael F., Friend, Daniel S., Stevens, Richard L., Anastasi, John, Singh, Harinder

“…PU.1 and GATA transcription factors appear to antagonize each other's function in the development of distinct lineages of the hematopoietic system. In…”
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Optimization and application of a flow cytometric PU.1 assay for murine immune cells by Noel, Greg, DeKoter, Rodney P., Wang, Quan, Hexley, Philip, Ogle, Cora K.

“…PU.1 is a master transcription factor whose levels directly influence hematopoiesis, leukemia, susceptibility to sepsis, and macrophage function. Though…”
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The transcription factor PU.1 mediates enhancer-promoter looping that is required for IL-1β eRNA and mRNA transcription in mouse melanoma and macrophage cell lines by Ha, Soon-Duck, Cho, Woohyun, DeKoter, Rodney P., Kim, Sung Ouk

“…The DNA-binding protein PU.1 is a myeloid lineage–determining and pioneering transcription factor due to its ability to bind “closed” genomic sites and…”
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EZH2 inhibition stimulates repetitive element expression and viral mimicry in resting splenic B cells by Kim, Seung J, Kiser, Patti K, Asfaha, Samuel, DeKoter, Rodney P, Dick, Frederick A

“…Mammalian cells repress expression of repetitive genomic sequences by forming heterochromatin. However, the consequences of ectopic repeat expression remain…”
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Expression and secretion of galectin‐12 in the context of neutrophilic differentiation of human promyeloblastic HL‐60 cells by Tazhitdinova, Rada, Cristiano, Sara, Yi, Joshua, Zhurov, Vladimir, DeKoter, Rodney P., Timoshenko, Alexander V.

“…Galectin‐12 is a tissue‐specific galectin that has been largely defined by its role in the regulation of adipocyte differentiation and lipogenesis. This study…”
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Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling by Mullen, Alan C., Orlando, David A., Newman, Jamie J., Lovén, Jakob, Kumar, Roshan M., Bilodeau, Steve, Reddy, Jessica, Guenther, Matthew G., DeKoter, Rodney P., Young, Richard A.

“…Transforming growth factor beta (TGF-β) signaling, mediated through the transcription factors Smad2 and Smad3 (Smad2/3), directs different responses in…”
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N-Acetylcysteine Alters Disease Progression and Increases Janus Kinase Mutation Frequency in a Mouse Model of Precursor B-Cell Acute Lymphoblastic Leukemia by Sams, Mia P, Iansavitchous, James, Astridge, Madeline, Rysan, Heidi, Xu, Li S, Rodrigues de Oliveira, Bruno, DeKoter, Rodney P

“…B-cell acute lymphoblastic leukemia (B-ALL) is the most prevalent type of cancer in young children and is associated with high levels of reactive oxygen…”
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Negative regulation of activation-induced cytidine deaminase gene transcription in developing B cells by a PU.1-interacting intronic region by MacKenzie, Allanna C.E., Sams, Mia P., Lin, Jane, Batista, Carolina Reyes, Lim, Michelle, Riarh, Chanpreet K., DeKoter, Rodney P.

“…Activation-induced cytidine deaminase (AID, encoded by Aicda) plays a key role in somatic hypermutation and class switch recombination in germinal center B…”
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