Search Results - "DeJesus, O.T."

Aromatic l-amino acid decarboxylase turnover in vivo in rhesus macaque striatum: A microPET study by DeJesus, O.T., Flores, L.G., Murali, D., Converse, A.K., Bartlett, R.M., Barnhart, T.E., Oakes, T.R., Nickles, R.J.

“…The aromatic l-amino acid decarboxylase (AAAD) is involved in the de novo synthesis of dopamine, a neurotransmitter crucial in cognitive, neurobehavioral and…”
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Positron emission tomography (PET) of radiotracer uptake and distribution in living plants: methodological aspects by Converse, A. K., Ahlers, E. O., Bryan, T. W., Williams, P. H., Barnhart, T. E., Engle, J. W., Nickles, R. J., DeJesus, O. T.

“…The use of radioisotopes as tracers in biology was pioneered in 1923 by Hevesy in the study of the uptake and distribution of lead in the bean plant. This…”
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An Efficient Synthesis of Dopamine Transporter Tracer [18F]FECNT1 by Murali, D., Barnhart, T.E., Vandehey, N.T., Christian, B.T., Nickles, R.J., Converse, A.K., Larson, J.A., Holden, J.E., Schneider, M.L., DeJesus, O.T.

“…A simple synthesis of the dopamine transporter ligand [ 18 F]FECNT with high radiochemical yield and short synthesis time, suitable for routine production is…”
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An efficient synthesis of dopamine transporter tracer [18F]FECNT by Murali, D., Barnhart, T.E., Vandehey, N.T., Christian, B.T., Nickles, R.J., Converse, A.K., Larson, J.A., Holden, J.E., Schneider, M.L., DeJesus, O.T.

“…A simple synthesis of the dopamine transporter ligand [18F]FECNT with high radiochemical yield and short synthesis time, suitable for routine production is…”
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p-[ 18F]-MPPF PET imaging of 5-HT1A receptor binding in marmoset brain by Converse, Alexander K., Aubert, Y., Murali, D., Weichert, J.P., DeJesus, O.T., Nickles, R.J., Abbott, D.H.

“…[1] Kemp, B.J., Lenox, M.W., Newport, D.F., Siegel, S.B., Nutt, R.E. Performance measurements of the Siemens Inveon small animal PET scanner (poster M14-69)…”
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FluoroDOPA PET shows the nondopaminergic as well as dopaminergic destinations of levodopa by BROWN, W. D, TAYLOR, M. D, ROBERTS, A. D, OAKES, T. R, SCHUELLER, M. J, HOLDEN, J. E, MALISCHKE, L. M, DEJESUS, O. T, NICKLES, R. J

“…To evaluate the visible and quantitative anatomic distribution of fluorine-18-labeled L-DOPA in the healthy human brain, to thereby expand the understanding of…”
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Prenatal stress, moderate fetal alcohol, and dopamine system function in rhesus monkeys by Roberts, A.D, Moore, C.F, DeJesus, O.T, Barnhart, T.E, Larson, J.A, Mukherjee, J, Nickles, R.J, Schueller, M.J, Shelton, S.E, Schneider, M.L

“…This study examined the striatal dopamine system integrity and associated behavior in 5- to 7-year-old rhesus monkeys born from mothers that experienced stress…”
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Simultaneous dual tracer PET imaging of alterations in dopamine D2 receptor occupancy and blood flow in rat brain by Converse, Alexander K., Moirano, J.M., Vandehey, N.T., Murali, D., Flores, L.G., Oakes, T.R., Holden, J.E., Roberts, A.D., Ruth, T.j., DeJesus, O.T., Nickles, R.j., Davidson, R.J.

“…If variations in dopamine receptor ligand binding (delta-BP) and blood flow (delta-rCBF) are measured separately, then intra-individual inter-scan variation is…”
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Aromatic l-amino acid decarboxylase (AAAD) activity in rhesus macaque striatum after MAO-B inhibition by Ro 16-6491 by Dejesus, O.T., Flores, L.G., Roberts, A.D., Dick, D.W., Bartlett, R.M., Murali, D., Nickles, R.J.

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Aromatic l-amino acid decarboxylase (AAAD) inhibitors as carcinoid tumor-imaging agents: synthesis of 18F-labeled α-fluoromethyl-6-fluoro- m-tyrosine (FM-6-FmT) by Murali, D., Flores, L.G., Roberts, A.D., Nickles, R.J., DeJesus, O.T.

“…The aromatic l-amino acid decarboxylase (AAAD) enzyme is significantly upregulated in neuroendocrine tumors and, thus, would be a good target for PET imaging…”
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Synthesis of 18F-6-FD by DeJesus, O T, Sunderland, J J, Nickles, R

“…Short communication…”
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Evaluation of 3-[18F]fluoro-alpha-fluoromethyl-p-tyrosine as a tracer for striatal tyrosine hydroxylase activity by DeJesus, O T, Murali, D, Kitchen, R, Endres, C, Oakes, T R, Shelton, S E, Freund, L, Houser, D, Uno, H, Holden, J E

“…3-[18F]Fluoro-alpha-fluoromethyl-p-tyrosine (3-F-FMPT) was evaluated as a tracer for CNS tyrosine hydroxylase (TH) activity in rodents and in a rhesus monkey…”
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Evaluation of positron-emitting SCH 23390 analogs as tracers for CNS dopamine D1 receptors by DeJesus, O T, Van Moffaert, G J, Friedman, A M

“…Two positron-emitting analogs of SCH 23390, one labelled with 75Br (or 76Br) and another with 11C, were evaluated as potential PET tracers for central dopamine…”
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Synthesis of [11C]SCH 23390 for dopamine D1 receptor studies by DeJesus, O T, Van Moffaert, G J, Friedman, A M

“…The optimal conditions for the synthesis of 11C-labelled SCH 23390 by radio-methylation of its desmethyl precursor, SCH 24518, with [11C]iodomethane are…”
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[18F]fluoride from a small cyclotron for the routine synthesis of [18F]2-fluoro-2-deoxy-D-glucose by Dejesus, O T, Martin, J A, Yasillo, N J, Gatley, S J, Cooper, M D

“…[18F]Fluoride was produced via the 18O (p, n) 18F reaction using a low volume stainless steel 18O-water target in a small cyclotron. The average 18F production…”
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