Search Results - "DeHart, Jason L"

HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system by DeHart, Jason L, Zimmerman, Erik S, Ardon, Orly, Monteiro-Filho, Carlos M R, Argañaraz, Enrique R, Planelles, Vicente

“…HIV-1 Vpr is a viral accessory protein that activates ATR through the induction of DNA replication stress. ATR activation results in cell cycle arrest in G2…”
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Human Immunodeficiency Virus Type 1 Vif Induces Cell Cycle Delay via Recruitment of the Same E3 Ubiquitin Ligase Complex That Targets APOBEC3 Proteins for Degradation by DEHART, Jason L, BOSQUE, Alberto, HARRIS, Reuben S, PLANELLES, Vicente

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HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT by Andersen, Joshua L, DeHart, Jason L, Zimmerman, Erik S, Ardon, Orly, Kim, Baek, Jacquot, Guillaume, Benichou, Serge, Planelles, Vicente

“…The HIV-1 accessory protein viral protein R (Vpr) causes G2 arrest and apoptosis in infected cells. We previously identified the DNA damage-signaling protein…”
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Human Immunodeficiency Virus Type 1 Vpr-Mediated G2 Arrest Requires Rad17 and Hus1 and Induces Nuclear BRCA1 and γ-H2AX Focus Formation by Zimmerman, Erik S., Chen, Junjie, Andersen, Joshua L., Ardon, Orly, DeHart, Jason L., Blackett, Jana, Choudhary, Shailesh K., Camerini, David, Nghiem, Paul, Planelles, Vicente

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Induction of G2 Arrest and Binding to Cyclophilin A Are Independent Phenotypes of Human Immunodeficiency Virus Type 1 Vpr by ARDON, Orly, ZIMMERMAN, Erik S, ANDERSEN, Joshua L, DEHART, Jason L, BLACKETT, Jana, PLANELLES, Vicente

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The Ataxia Telangiectasia-Mutated and Rad3-Related Protein Is Dispensable for Retroviral Integration by DEHART, Jason L, ANDERSEN, Joshua L, ZIMMERMAN, Erik S, ARDON, Orly, DONG SUNG AN, BLACKETT, Jana, KIM, Baek, PLANELLES, Vicente

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Self-Replicating RNAs Drive Protective Anti-tumor T Cell Responses to Neoantigen Vaccine Targets in a Combinatorial Approach by Maine, Christian J., Richard, Guilhem, Spasova, Darina S., Miyake-Stoner, Shigeki J., Sparks, Jessica, Moise, Leonard, Sullivan, Ryan P., Garijo, Olivia, Choz, Melissa, Crouse, Jenna M., Aguilar, Allison, Olesiuk, Melanie D., Lyons, Katie, Salvador, Katrina, Blomgren, Melissa, DeHart, Jason L., Kamrud, Kurt I., Berdugo, Gad, De Groot, Anne S., Wang, Nathaniel S., Aliahmad, Parinaz

“…Historically poor clinical results of tumor vaccines have been attributed to weakly immunogenic antigen targets, limited specificity, and vaccine platforms…”
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Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation by Dehart, Jason L, Planelles, Vicente

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CD8 + T cells mediate protection against Zika virus induced by an NS3-based vaccine by Elong Ngono, Annie, Syed, Thasneem, Nguyen, Anh-Viet, Regla-Nava, Jose Angel, Susantono, Mercylia, Spasova, Darina, Aguilar, Allison, West, Melissa, Sparks, Jessica, Gonzalez, Andrew, Branche, Emilie, DeHart, Jason L, Vega, Jerel Boyd, Karmali, Priya Prakash, Chivukula, Padmanabh, Kamrud, Kurt, Aliahmad, Parinaz, Wang, Nathaniel, Shresta, Sujan

“…Zika virus (ZIKV) is associated with congenital malformations in infants born to infected mothers, and with Guillain-Barré syndrome in infected adults…”
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Human Immunodeficiency Virus Type 1 Vpr Links Proteasomal Degradation and Checkpoint Activation by DEHART, Jason L, PLANELLES, Vicente

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CD8+ T cells mediate an NS3-based vaccine protection against Zika virus by Ngono, Annie Elong, Syed, Thasneem, Nguyen, Anh-Viet, Nava, Jose Regla, Susantono, Mercylia, Spasova, Darina, Aguilar, Allison, West, Melissa, Sparks, Jessica, Gonzalez, Andrew, Branche, Emilie, DeHart, Jason L., Kamrud, Kurt, Aliahmad, Parinaz, Wang, Nathaniel, Shresta, Sujan

“…Abstract Zika virus (ZIKV), a member of the flaviviridae family, is associated with severe congenital malformations in infants born to infected mothers, and…”
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Induction of G 2 Arrest and Binding to Cyclophilin A Are Independent Phenotypes of Human Immunodeficiency Virus Type 1 Vpr by Ardon, Orly, Zimmerman, Erik S., Andersen, Joshua L., DeHart, Jason L., Blackett, Jana, Planelles, Vicente

“…ABSTRACT Cyclophilin A (CypA) is a member of a family of cellular proteins that share a peptidyl prolyl cis-trans isomerase (PPIase) activity. CypA was…”
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Induction of G sub(2) Arrest and Binding to Cyclophilin A Are Independent Phenotypes of Human Immunodeficiency Virus Type 1 Vpr by Ardon, Orly, Zimmerman, Erik S, Andersen, Joshua L, DeHart, Jason L, Blackett, Jana, Planelles, Vicente

“…Cyclophilin A (CypA) is a member of a family of cellular proteins that share a peptidyl prolyl cis-trans isomerase (PPIase) activity. CypA was previously…”
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Human Immunodeficiency Virus Type 1 Vpr-Mediated G sub(2) Arrest Requires Rad17 and Hus1 and Induces Nuclear BRCA1 and gamma -H2AX Focus Formation by Zimmerman, Erik S, Chen, Junjie, Andersen, Joshua L, Ardon, Orly, Dehart, Jason L, Blackett, Jana, Choudhary, Shailesh K, Camerini, David, Nghiem, Paul, Planelles, Vicente

“…Eukaryotic cells have evolved a complex mechanism for sensing DNA damage during genome replication. Activation of this pathway prevents entry into mitosis to…”
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Human Immunodeficiency Virus Type 1 Vpr-Mediated G 2 Arrest Requires Rad17 and Hus1 and Induces Nuclear BRCA1 and γ-H2AX Focus Formation by Zimmerman, Erik S., Chen, Junjie, Andersen, Joshua L., Ardon, Orly, DeHart, Jason L., Blackett, Jana, Choudhary, Shailesh K., Camerini, David, Nghiem, Paul, Planelles, Vicente

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