Search Results - "DeFife, Kristin M."

Disruption of filamentous actin inhibits human macrophage fusion by Defife, Kristin M., Jenney, Christopher R., Colton, Erica, Anderson, James M.

“…ABSTRACT The foreign body reaction to implanted biomaterials, characterized by the presence of macrophages and foreign body giant cells (FBGC), can result in…”
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Poly(ester amide) Co-polymers Promote Blood and Tissue Compatibility by DeFife, Kristin M., Grako, Kathy, Cruz-Aranda, Gina, Price, Sharon, Chantung, Ron, Macpherson, Kassie, Khoshabeh, Ramina, Gopalan, Sindhu, Turnell, William G.

“…A family of biodegradable poly(ester amide) (PEA) co-polymers based on naturally occurring α-amino acids has been developed for applications ranging from…”
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Interleukin-4-induced macrophage fusion is prevented by inhibitors of mannose receptor activity by McNally, AK, DeFife, KM, Anderson, JM

“…A potential role for the macrophage mannose receptor in human monocyte-derived macrophage fusion was explored by testing the effects of previously described…”
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Cytoskeletal and Adhesive Structural Polarizations Accompany IL-13-induced Human Macrophage Fusion by DeFife, Kristin M, Jenney, Chris R, Colton, Erica, Anderson, James M

“…During the inflammatory response to an implanted biomaterial, monocytes undergo a striking phenotypic progression of differentiation into macrophages, which…”
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Integrated approaches to therapeutic target gene discovery by DeFife, Kristin M, Wong-Staal, Flossie

“…The identification of tractable drug targets is the first critical step in the long process of drug development, and the challenge for scientists in the…”
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Interleukin-13 induces human monocyte/macrophage fusion and macrophage mannose receptor expression by DeFife, KM, Jenney, CR, McNally, AK, Colton, E, Anderson, JM

“…Inasmuch as we recently demonstrated that IL-4 is a strong inducer of monocyte/macrophage fusion and IL-13 has been observed to mimic many of the biologic…”
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Effects of photochemically immobilized polymer coatings on protein adsorption, cell adhesion, and the foreign body reaction to silicone rubber by DeFife, Kristin M., Shive, Matthew S., Hagen, Kris M., Clapper, David L., Anderson, James M.

“…Photochemical immobilization technology was utilized to covalently couple polymers to silicone rubber either at multiple points along a polymer backbone or at…”
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Vitamin E as an antioxidant for poly(etherurethane urea): In vivo studies by Schubert, Mark A., Wiggins, Michael J., DeFife, Kristin M., Hiltner, Anne, Anderson, James M.

“…Poly(etherurethane) elastomers are useful materials in medical devices because of their mechanical properties and biocompatibility. However, it is necessary to…”
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Photochemically immobilized polymer coatings: effects on protein adsorption, cell adhesion, and leukocyte activation by Defife, Kristin M., Hagen, Kris M., Clapper, David L., Anderson, James M.

“…Amphiphilic chains of 4-benzoylbenzoic acid moieties and polymer were photochemically immobilized onto silicone rubber to ask whether the covalently coupled…”
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Human monocyte/macrophage adhesion, macrophage motility, and IL-4-induced foreign body giant cell formation on silane-modified surfaces in vitro by Jenney, Christopher R., DeFife, Kristin M., Colton, Erica, Anderson, James M.

“…A cytokine‐based, in vitro model of foreign body giant cell (FBGC) formation was utilized to examine the effect of biomaterial surface chemistry on the…”
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Spatial regulation and surface chemistry control of monocyte/macrophage adhesion and foreign body giant cell formation by photochemically micropatterned surfaces by DeFife, Kristin M., Colton, Erica, Nakayama, Yasuhide, Matsuda, Takehisa, Anderson, James M.

“…A long‐standing goal of biomedical device development has been the generation of specific, desired host blood and tissue responses. An approach to meeting this…”
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Human monocyte/macrophage adhesion, macrophage motility, and IL-4-induced foreign body giant cell formation on silane-modified surfacesin vitro by Jenney, Christopher R., DeFife, Kristin M., Colton, Erica, Anderson, James M.

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