Search Results - "DeFelice, L.J"
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Novel fluorescence-based approaches for the study of biogenic amine transporter localization, activity, and regulation
Published in Journal of neuroscience methods (15-04-2005)“…Pre-synaptic norepinephrine (NE) and dopamine (DA) transporters (NET and DAT) terminate catecholamine synaptic transmission through reuptake of released…”
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Inactivation of L-type Ca channels in embryonic chick ventricle cells: dependence on the cytoskeletal agents colchicine and taxol
Published in Biophysical journal (01-12-1994)“…This article shows that colchicine and taxol strongly influence the kinetics of L-type Ca channels in intact cardiac cells, and it suggests a mechanism for…”
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Drosophila Serotonin Transporters Have Voltage-Dependent Uptake Coupled to a Serotonin-Gated Ion Channel
Published in The Journal of neuroscience (15-05-1997)“…Serotonin (5HT) transporters (SERTs) couple to existing ion gradients to transport 5HT into presynaptic terminals. In mammalian SERTs, the transport cycle is…”
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Relationship between membrane excitability and single channel open-close kinetics
Published in Biophysical journal (01-05-1983)“…We have developed a novel technique for simulating the influence of the effects of single channel kinetics on the voltage changes associated with membrane…”
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Pore models for transporters?
Published in Biophysical journal (01-02-1996)Get full text
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Release of secretory vesicle contents: regulation after fusion?
Published in Biophysical journal (01-09-1996)Get full text
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Na channels that remain open throughout the cardiac action potential plateau
Published in Biophysical journal (01-09-1992)“…In this paper we report the direct measurement of rare Na channel events that occur during the cardiac action potential, viz., channels that open at the…”
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Ca channel gating during cardiac action potentials
Published in Biophysical journal (01-10-1990)“…How do Ca channels conduct Ca ions during the cardiac action potential? We attempt to answer this question by applying a two-microelectrode technique,…”
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Ca channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells
Published in Biophysical journal (01-09-1993)“…The ability of Ca ions to inhibit Ca channels presents one of the most intriguing problems in membrane biophysics. Because of this negative feedback, Ca…”
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How ATP regulates the CFT regulator
Published in Biophysical journal (01-05-1994)Get full text
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Gating currents. Machinery behind the molecule
Published in Biophysical journal (1993)“…Na channels equip cells to generate and propagate electrical signals. The Na channel works because it can sense membrane voltage. But how does voltage…”
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Na channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells
Published in Biophysical journal (01-07-1987)“…Using cell-attached and whole-cell recording techniques simultaneously allows the measurement of Na currents during action potentials in beating heart cells…”
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Calcium and potassium currents in porcine granulosa cells maintained in follicular or monolayer tissue culture
Published in The Journal of membrane biology (01-05-1993)“…We studied membrane currents in granulosa cells (GC), immediately after collection or after variable culture time in the everted-follicle wall or in the…”
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K channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells
Published in Biophysical journal (01-12-1988)“…By averaging the current that passes through cell-attached patches on beating heart cells, while measuring action potentials with a whole-cell electrode, we…”
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L-type Ca2+ currents in ascidian eggs
Published in Experimental cell research (01-01-1991)“…We have studied Ca2+ currents in ascidian eggs using the whole-cell clamp technique. T and L components, as observed in somatic cells, are present and the…”
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Regulation of the Na-conducting Ca channel during the cardiac action potential
Published in Biophysical journal (1987)“…This paper describes the kinetics of an Na-conducting channel during spontaneous action potentials in beating heart cells and during simulated action…”
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Outward sodium current in beating heart cells
Published in Biophysical journal (1990)“…This article is a study of the fast Na current during action potentials. We have investigated the outward Na current (Mazzanti, M., and L.J. DeFelice. 1987…”
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Sodium-conducting channels in cardiac membranes in low calcium
Published in Biophysical journal (01-07-1986)“…With no Ca in the patch electrode, two kinds of channels conduct Na in spontaneously beating embryonic chick heart cells. One channel conducts Na primarily…”
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Membrane noise
Published in Progress in biophysics and molecular biology (1974)Get more information
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