Search Results - "DeFelice, L J"

Novel fluorescence-based approaches for the study of biogenic amine transporter localization, activity, and regulation by Mason, J.N., Farmer, H., Tomlinson, I.D., Schwartz, J.W., Savchenko, V., DeFelice, L.J., Rosenthal, S.J., Blakely, R.D.

“…Pre-synaptic norepinephrine (NE) and dopamine (DA) transporters (NET and DAT) terminate catecholamine synaptic transmission through reuptake of released…”
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Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins by Blakely, Randy D., Ramamoorthy, Sammanda, Schroeter, Sally, Qian, Yan, Apparsundaram, Subramaniam, Galli, Aurelio, DeFelice, Louis J.

“…Presynaptic serotonin (5-hydroxytryptamine, 5-HT) transporters (SERTs) mediate antidepressant-sensitive clearance of 5-HT following release. Although we have…”
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Norepinephrine Transporters have Channel Modes of Conduction by Galli, Aurelio, Blakely, Randy D., DeFelice, Louis J.

“…Neurotransmitter transporters couple to existing ion gradients to achieve reuptake of transmitter into presynaptic terminals. For coupled cotransport,…”
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Inactivation of L-type Ca channels in embryonic chick ventricle cells: dependence on the cytoskeletal agents colchicine and taxol by Galli, A., DeFelice, L.J.

“…This article shows that colchicine and taxol strongly influence the kinetics of L-type Ca channels in intact cardiac cells, and it suggests a mechanism for…”
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Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants by Galli, A, DeFelice, L J, Duke, B J, Moore, K R, Blakely, R D

“…Transport of norepinephrine (NE+) by cocaine- and antidepressant-sensitive transporters in presynaptic terminals is predicted to involve the cotransport of Na+…”
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Pore models for transporters? by DeFelice, L.J., Blakely, R.D.

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Drosophila Serotonin Transporters Have Voltage-Dependent Uptake Coupled to a Serotonin-Gated Ion Channel by Galli, A, Petersen, C.I, deBlaquiere, M, Blakely, R.D, DeFelice, L.J

“…Serotonin (5HT) transporters (SERTs) couple to existing ion gradients to transport 5HT into presynaptic terminals. In mammalian SERTs, the transport cycle is…”
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Gating of L-type Ca2+ channels in embryonic chick ventricle cells: dependence on voltage, current and channel density by Mazzanti, M, DeFelice, L J, Liu, Y M

“…1. L-type calcium channels in embryonic chick heart ventricle have voltage-dependent, time-variant kinetics when they conduct inward currents carried by 20…”
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Sodium-dependent GABA-induced currents in GAT1-transfected HeLa cells by Risso, S, DeFelice, L J, Blakely, R D

“…1. HeLa cells were infected with recombinant vaccinia virus containing the T7 RNA polymerase gene and transfected with the cDNA for a rat GABA transporter,…”
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Ion channels in the nuclear envelope by Mazzanti, Michele, DeFelice, Louis J, Cohen, Jacques, Malter, Henry

“…Cell nuclei are capable of partitioning a wide variety of molecules from the cytosol, including macromolecules such as proteins and RNA, and smaller peptides,…”
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Na channels that remain open throughout the cardiac action potential plateau by Liu, Y.M., DeFelice, L.J., Mazzanti, M.

“…In this paper we report the direct measurement of rare Na channel events that occur during the cardiac action potential, viz., channels that open at the…”
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Transporter structure and mechanism by DeFelice, Louis J

“…During the past several decades, lac permease has assumed almost tutelary proportions as a model for cotransporters. This archetypical membrane protein now…”
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Ca channel gating during cardiac action potentials by Mazzanti, M., DeFelice, L.J.

“…How do Ca channels conduct Ca ions during the cardiac action potential? We attempt to answer this question by applying a two-microelectrode technique,…”
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Ca channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells by Risso, S., DeFelice, L.J.

“…The ability of Ca ions to inhibit Ca channels presents one of the most intriguing problems in membrane biophysics. Because of this negative feedback, Ca…”
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Differential regulation of mammalian brain‐specific proline transporter by calcium and calcium‐dependent protein kinases by Jayanthi, Lankupalle D, Wilson, Jennifer J, Montalvo, Jocelyn, DeFelice, Louis J

“…This study examined the role of [Ca2+]I and Ca2+‐dependent kinases in the modulation of high‐affinity, mammalian brain‐specific L‐proline transporter (PROT)…”
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Molecular microfluorometry: converting arbitrary fluorescence units into absolute molecular concentrations to study binding kinetics and stoichiometry in transporters by Schwartz, J W, Piston, D, DeFelice, L J

“…Cotransporters use energy stored in Na+ or H+ gradients to transport neurotransmitters or other substrates against their own gradient. Cotransport is rapid and…”
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Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression by Qian, Yan, Galli, Aurelio, Ramamoorthy, Sammanda, Risso, Stefania, DeFelice, Louis J, Blakely, Randy D

“…Antidepressant- and cocaine-sensitive serotonin (5-hydroxytryptamine, 5-HT) transporters (SERTs) dictate clearance of extracellular 5-HT after release. To…”
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Molecular and biophysical view of the Ca channel : a hypothesis regarding oligomeric structure, channel clustering, and macroscopic current by DEFELICE, L. J

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Na channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells by Mazzanti, M., DeFelice, L.J.

“…Using cell-attached and whole-cell recording techniques simultaneously allows the measurement of Na currents during action potentials in beating heart cells…”
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Calcium and potassium currents in porcine granulosa cells maintained in follicular or monolayer tissue culture by MATTIOLI, M, BARBONI, B, DEFELICE, L. J

“…We studied membrane currents in granulosa cells (GC), immediately after collection or after variable culture time in the everted-follicle wall or in the…”
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