Search Results - "DeFelice, J"

Bringing CLARITY to the human brain: visualization of Lewy pathology in three dimensions by Liu, A. K. L., Hurry, M. E. D., Ng, O.T. W., DeFelice, J., Lai, H. M., Pearce, R. K. B., Wong, G. T-C., Chang, R. C-C., Gentleman, S. M.

“…Aims CLARITY is a novel technique which enables three‐dimensional visualization of immunostained tissue for the study of circuitry and spatial interactions…”
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Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission by Carvelli, Lucia, Blakely, Randy D, DeFelice, Louis J

“…The Caenorhabditis elegans (C. elegans) dopamine (DA) transporter (DAT-1) regulates DA signaling through efficient DA reuptake following synaptic release. In…”
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Transporters as channels by DeFelice, Louis J, Goswami, Tapasree

“…This review investigates some key aspects of transport mechanisms and recent advances in our understanding of this ubiquitous cellular process. The prevailing…”
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Dopamine Transporters Depolarize Neurons by a Channel Mechanism by Carvelli, Lucia, McDonald, Paul W., Blakely, Randy D., DeFelice, Louis J., Amara, Susan G.

“…Neurotransmitter transporters generate larger currents than expected if one assumes fixed stoichiometry models. It remains controversial, however, whether…”
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PP 7.3 – 00010 Virion Immunocapture Reveals Low-level Myeloid-derived HIV Expression in Semen under INSTI-based Therapy is Disparate from Circulating Seminal and Blood Proviral Sequences by J. Johnson, J.F. Li, J. Politch, J. Lipscomb, J. Defelice, M. Gelman, K. Mayer, D. Anderson

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Transporter structure and mechanism by DeFelice, Louis J

“…During the past several decades, lac permease has assumed almost tutelary proportions as a model for cotransporters. This archetypical membrane protein now…”
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Biogenic Amine Neurotransmitter Transporters: Just When You Thought You Knew Them by Blakely, Randy D, DeFelice, Louis J, Galli, Aurelio

“…Randy D. Blakely , Louis J. DeFelice and Aurelio Galli Departments of Pharmacology, Molecular Physiology and Biophysics, and Psychiatry, and Center for…”
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Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression by Qian, Yan, Galli, Aurelio, Ramamoorthy, Sammanda, Risso, Stefania, DeFelice, Louis J, Blakely, Randy D

“…Antidepressant- and cocaine-sensitive serotonin (5-hydroxytryptamine, 5-HT) transporters (SERTs) dictate clearance of extracellular 5-HT after release. To…”
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A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway by Xu, Haoxing, Jin, Jie, DeFelice, Louis J, Andrews, Nancy C, Clapham, David E

“…Divalent metal transporter-1 (DMT1/DCT1/Nramp2) is the major Fe(2+) transporter mediating cellular iron uptake in mammals. Phenotypic analyses of animals with…”
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Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins by Blakely, Randy D., Ramamoorthy, Sammanda, Schroeter, Sally, Qian, Yan, Apparsundaram, Subramaniam, Galli, Aurelio, DeFelice, Louis J.

“…Presynaptic serotonin (5-hydroxytryptamine, 5-HT) transporters (SERTs) mediate antidepressant-sensitive clearance of 5-HT following release. Although we have…”
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HIV particles expressed in semen under INSTI-based suppressive therapy are largely myeloid cell-derived and exhibit widely diverse genotypes by J. Johnson, D. Anderson, J.F. Li, A. Santos Tino, J. Politch, J. Lipscomb, J. Defelice, M. Gelman, K. Mayer

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HIV particles expressed in semen under INSTI-based suppressive therapy are largely myeloid cell-derived and exhibit widely diverse genotypes by J. Johnson, D. Anderson, J.F. Li, A. Santos Tino, J. Politch, J. Lipscomb, J. Defelice, M. Gelman, K. Mayer

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Targeting Cell Surface Receptors with Ligand-Conjugated Nanocrystals by Rosenthal, Sandra J, Tomlinson, Ian, Adkins, Erika M, Schroeter, Sally, Adams, Scott, Swafford, Laura, McBride, James, Wang, Yongqiang, DeFelice, Louis J, Blakely, Randy D

“…To explore the potential for use of ligand-conjugated nanocrystals to target cell surface receptors, ion channels, and transporters, we explored the ability of…”
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Substrate Binding Stoichiometry and Kinetics of the Norepinephrine Transporter by Schwartz, Joel W., Novarino, Gaia, Piston, David W., DeFelice, Louis J.

“…The human norepinephrine (NE) transporter (hNET) attenuates neuronal signaling by rapid NE clearance from the synaptic cleft, and NET is a target for cocaine…”
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Flux Coupling in the Human Serotonin Transporter by Adams, Scott V., DeFelice, Louis J.

“…The serotonin (5-hydroxytryptamine; 5HT) transporter (SERT) catalyzes the movement of 5HT across cellular membranes. In the brain, SERT clears 5HT from…”
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Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells by Apparsundaram, S, Galli, A, DeFelice, L J, Hartzell, H C, Blakely, R D

“…Using SK-N-SH cells, we observe that muscarinic acetylcholine receptor activation by methacholine (MCh) rapidly and selectively diminishes l-NE transport…”
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Patch-Clamp and Amperometric Recordings from Norepinephrine Transporters: Channel Activity and Voltage-Dependent Uptake by Galli, Aurelio, Blakely, Randy D., DeFelice, Louis J.

“…Transporters for the biogenic amines dopamine, norepinephrine, epinephrine and serotonin are largely responsible for transmitter inactivation after release…”
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All aglow about presynaptic receptor regulation of neurotransmitter transporters by Blakely, Randy D, DeFelice, Louis J

“…Mounting evidence supports the idea that neurotransmitter transporters are subject to many forms of post-translational regulation typically associated with…”
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Serotonin transporter function and pharmacology are sensitive to expression level: evidence for an endogenous regulatory factor by Ramsey, I Scott, DeFelice, Louis J

“…We express mammalian serotonin transporters (SERTs) in Xenopus oocytes by cRNA injection and measure 5-hydroxytryptamine (5-HT) transport and 5-HT-induced…”
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Norepinephrine Transporters have Channel Modes of Conduction by Galli, Aurelio, Blakely, Randy D., DeFelice, Louis J.

“…Neurotransmitter transporters couple to existing ion gradients to achieve reuptake of transmitter into presynaptic terminals. For coupled cotransport,…”
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