Search Results - "DeFazio, R. Anthony"

A role for glial fibrillary acidic protein (GFAP)-expressing cells in the regulation of gonadotropin-releasing hormone (GnRH) but not arcuate kisspeptin neuron output in male mice by Vanacker, Charlotte, Defazio, R Anthony, Sykes, Charlene M, Moenter, Suzanne M

“…GnRH neurons are the final central neural output regulating fertility. Kisspeptin neurons in the hypothalamic arcuate nucleus (KNDy neurons) are considered the…”
Get full text

Long-Term Recordings of Arcuate Nucleus Kisspeptin Neurons Reveal Patterned Activity That Is Modulated by Gonadal Steroids in Male Mice by Vanacker, Charlotte, Moya, Manuel Ricu, DeFazio, R. Anthony, Johnson, Michael L, Moenter, Suzanne M

“…Pulsatile release of gonadotropin-releasing hormone (GnRH) is key to fertility. Pulse frequency is modulated by gonadal steroids and likely arises subsequent…”
Get full text

GnRH neuron activity and pituitary response in estradiol-induced vs proestrous luteinizing hormone surges in female mice by Silveira, Marina, Burger, Laura L, DeFazio, R. Anthony, Wagenmaker, Elizabeth R, Moenter, Suzanne M

“…During the female reproductive cycle, estradiol exerts negative and positive feedback at both the central level to alter GnRH release and at the pituitary to…”
Get full text

Differential volatile signatures from skin, naevi and melanoma: a novel approach to detect a pathological process by Abaffy, Tatjana, Duncan, Robert, Riemer, Daniel D, Tietje, Olaf, Elgart, George, Milikowski, Clara, DeFazio, R Anthony

“…Early detection of melanoma is of great importance to reduce mortality. Discovering new melanoma biomarkers would improve early detection and diagnosis. Here,…”
Get full text

Changes in Both Neuron Intrinsic Properties and Neurotransmission Are Needed to Drive the Increase in GnRH Neuron Firing Rate during Estradiol-Positive Feedback by Adams, Caroline, DeFazio, R Anthony, Christian, Catherine A, Milescu, Lorin S, Schnell, Santiago, Moenter, Suzanne M

“…Central output of gonadotropin-releasing hormone (GnRH) neurons controls fertility and is sculpted by sex-steroid feedback. A switch of estradiol action from…”
Get full text

Estradiol Enhances the Depolarizing Response to GABA and AMPA Synaptic Conductances in Arcuate Kisspeptin Neurons by Diminishing Voltage-Gated Potassium Currents by DeFazio, R Anthony, Navarro, Marco A, Adams, Caroline E, Milescu, Lorin S, Moenter, Suzanne M

“…Synaptic and intrinsic properties interact to sculpt neuronal output. Kisspeptin neurons in the hypothalamic arcuate nucleus help convey homeostatic estradiol…”
Get full text

Voltage-Gated Potassium Currents Are Targets of Diurnal Changes in Estradiol Feedback Regulation and Kisspeptin Action on Gonadotropin-Releasing Hormone Neurons in Mice by PIELECKA-FORTUNA, Justyna, ANTHONY DEFAZIO, R, MOENTER, Suzanne M

“…Estradiol has both negative and positive feedback actions upon gonadotropin-releasing hormone (GnRH) release; the latter actions trigger the preovulatory GnRH…”
Get full text

Reciprocal Changes in Voltage-Gated Potassium and Subthreshold Inward Currents Help Maintain Firing Dynamics of AVPV Kisspeptin Neurons during the Estrous Cycle by Starrett, J. Rudolph, DeFazio, R. Anthony, Moenter, Suzanne M.

“…Abstract Kisspeptin-expressing neurons in the anteroventral-periventricular nucleus (AVPV) are part of a neural circuit generating the gonadotropin-releasing…”
Get full text

Firing patterns of gonadotropin-releasing hormone neurons are sculpted by their biologic state by Penix, Jonathon, DeFazio, R Anthony, Dulka, Eden A, Schnell, Santiago, Moenter, Suzanne M

“…Gonadotropin-releasing hormone (GnRH) neurons form the final pathway for the central neuronal control of fertility. GnRH is released in pulses that vary in…”
Get full text

Activation of protein kinase C delta following cerebral ischemia leads to release of cytochrome C from the mitochondria via bad pathway by Dave, Kunjan R, Bhattacharya, Sanjoy K, Saul, Isabel, DeFazio, R Anthony, Dezfulian, Cameron, Lin, Hung Wen, Raval, Ami P, Perez-Pinzon, Miguel A

“…The release of cytochrome c from the mitochondria following cerebral ischemia is a key event leading to cell death. The goal of the present study was to…”
Get full text

Estradiol-Sensitive Afferents Modulate Long-Term Episodic Firing Patterns of GnRH Neurons by Nunemaker, Craig S, DeFazio, R. Anthony, Moenter, Suzanne M

“…GnRH neurons comprise the final common pathway of an estrogen-sensitive pattern generator controlling fertility. To determine estradiol effects on GnRH neuron…”
Get full text

Estradiol Feedback Alters Potassium Currents and Firing Properties of Gonadotropin-Releasing Hormone Neurons by DeFazio, R. Anthony, Moenter, Suzanne M

“…GnRH neurons are regulated by estradiol feedback through unknown mechanisms. Voltage-gated potassium channels determine the pattern of activity and response to…”
Get full text

Development and prenatal exposure to androgens alter potassium currents in gonadotropin‐releasing hormone neurons from female mice by Jaime, Jennifer, DeFazio, R. Anthony, Moenter, Suzanne M.

“…Pulsatile gonadotropin‐releasing hormone (GnRH) release is critical for reproduction. Disruptions to GnRH secretion patterns may contribute to polycystic ovary…”
Get full text

The location of olfactory receptors within olfactory epithelium is independent of odorant volatility and solubility by Abaffy, Tatjana, Defazio, Anthony R

“…Our objective was to study the pattern of olfactory receptor expression within the dorsal and ventral regions of the mouse olfactory epithelium. We…”
Get full text

Metabolic Regulation of Fertility through Presynaptic and Postsynaptic Signaling to Gonadotropin-Releasing Hormone Neurons by Sullivan, Shannon D, DeFazio, R. Anthony, Moenter, Suzanne M

“…Gonadotropin-releasing hormone (GnRH) neurons form the final common pathway for the central regulation of reproduction and are inhibited by negative energy…”
Get full text

Gonadotropin-Releasing Hormone Neurons Generate Interacting Rhythms in Multiple Time Domains by Nunemaker, Craig S, Straume, Martin, DeFazio, R. Anthony, Moenter, Suzanne M

“…Pulsatile release of GnRH is prerequisite for fertility. The possibility that multiple rhythms interact to generate GnRH pulses was raised by observations of…”
Get full text

A targeted extracellular approach for recording long-term firing patterns of excitable cells: a practical guide by Nunemaker, Craig S., DeFazio, R Anthony, Moenter, Suzanne M.

“…Excitable cells in many endocrine and neuronal systems display rhythms with periodicities on the order of many minutes. To observe firing patterns that…”
Get full text

Optoα1AR activation in astrocytes modulates basal hippocampal synaptic excitation and inhibition in a stimulation‐specific manner by Courtney, Connor D., Sobieski, Courtney, Ramakrishnan, Charu, Ingram, Robbie J., Wojnowski, Natalia M., DeFazio, R. Anthony, Deisseroth, Karl, Christian‐Hinman, Catherine A.

“…Astrocytes play active roles at synapses and can monitor, respond, and adapt to local synaptic activity. While there is abundant evidence that astrocytes…”
Get full text

Calcium Current Subtypes in GnRH Neurons by NUNEMAKER, Craig S, DEFAZIO, R. Anthony, MOENTER, Suzanne M

“…Calcium plays roles in excitability, rhythm generation, and neurosecretion. Identifying channel subtypes that regulate calcium influx is thus important to…”
Get full text

Gonadotropin-Releasing Hormone (GnRH) Neuron Potassium Currents and Excitability in Both Sexes Exhibit Minimal Changes upon Removal of Negative Feedback by DeFazio, R Anthony, Moenter, Suzanne M

“…Gonadotropin-releasing hormone (GnRH) drives pituitary secretion of luteinizing hormone and follicle-stimulating hormone, which in turn regulate gonadal…”
Get full text