Search Results - "DeDionisio, Larry A."

Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders by Christie, Kathleen A., Courtney, David G., DeDionisio, Larry A., Shern, Connie Chao, De Majumdar, Shyamasree, Mairs, Laura C., Nesbit, M. Andrew, Moore, C. B. Tara

“…CRISPR/Cas9 holds immense potential to treat a range of genetic disorders. Allele-specific gene disruption induced by non-homologous end-joining (NHEJ) DNA…”
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Mutation-Independent Allele-Specific Editing by CRISPR-Cas9, a Novel Approach to Treat Autosomal Dominant Disease by Christie, Kathleen A., Robertson, Louise J., Conway, Caroline, Blighe, Kevin, DeDionisio, Larry A., Chao-Shern, Connie, Kowalczyk, Amanda M., Marshall, John, Turnbull, Doug, Nesbit, M. Andrew, Moore, C.B. Tara

“…CRISPR-Cas9 provides a tool to treat autosomal dominant disease by non-homologous end joining (NHEJ) gene disruption of the mutant allele. In order to…”
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Late-onset lattice corneal dystrophy associated TGFBI p.H626R mutation in members of a Canadian family by Chao-Shern, Connie, DeDionisio, Larry A., Chan, Clara C., Nesbit, M. Andrew, McMullen, C.B. Tara

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