Search Results - "DeDionisio, L"

Gene editing in the context of an increasingly complex genome by Blighe, K, DeDionisio, L, Christie, K A, Chawes, B, Shareef, S, Kakouli-Duarte, T, Chao-Shern, C, Harding, V, Kelly, R S, Castellano, L, Stebbing, J, Lasky-Su, J A, Nesbit, M A, Moore, C B T

“…The reporting of the first draft of the human genome in 2000 brought with it much hope for the future in what was felt as a paradigm shift toward improved…”
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Post-LASIK exacerbation of granular corneal dystrophy type 2 in members of a chinese family by Chao-Shern, C, Me, R, DeDionisio, L A, Ke, B L, Nesbit, M A, Marshall, J, Moore, C B T

“…Purpose The post-LASIK exacerbation of corneal dystrophy, otherwise asymptomatic, is almost exclusively associated with the TGFBI gene mutations at codon 124…”
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Effect of phosphorothioate modification of oligodeoxynucleotides on specific protein binding by Brown, D A, Kang, S H, Gryaznov, S M, DeDionisio, L, Heidenreich, O, Sullivan, S, Xu, X, Nerenberg, M I

“…Phosphorothioate modification of internucleoside linkages is widely used to prevent degradation of oligodeoxynucleotide (ODN) therapeutic agents in serum and…”
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Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides by Beltinger, C, Saragovi, H U, Smith, R M, LeSauteur, L, Shah, N, DeDionisio, L, Christensen, L, Raible, A, Jarett, L, Gewirtz, A M

“…An enhanced appreciation of uptake mechanisms and intracellular trafficking of phosphorothioate modified oligodeoxynucleotides (P-ODN) might facilitate the use…”
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Oligonucleotide N3' → P5' Phosphoramidates by Gryaznov, Sergei M., Lloyd, David H., Chen, Jer-Kang, Schultz, Ronald G., DeDionisio, Lawrence A., Ratmeyer, Lynda, Wilson, W. David

“…Synthetic oligonucleotides and their analogs have attracted considerable interest recently. These compounds may lead to highly specific therapeutic agents, as…”
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Analysis of modified oligonucleotides with capillary gel electrophoresis by DeDionisio, L A

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Associations between food habits and pharyngeal morphology in the round goby (Neogobius melanostomus) by Andraso, Greg, Blank, Noelle, Shadle, Matthew J., DeDionisio, Julie L., Ganger, Michael T.

“…Several studies have shown that round gobies ( Neogobius melanostomus ) undergo a dietary shift from arthropods to dreissenid mussels as they grow, and this…”
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An improved synthesis of oligodeoxynucleotide N3′→P5′ phosphoramidates and their chimera using hindered phosphoramidite monomers and a novel handle for reverse phase purification by Fearon, Karen L., Hirschbein, Bernard L., Nelson, Jeffrey S., Foy, Michael F., Nguyen, Mark Q., McCurdy, Sarah N., Frediani, Jeff E., DeDionisio, Lawrence A., Raible, Annette M., Cagle, E. Neil, Okruszek, Andrzej, Boyd, Vicky

“…Oligodeoxynucleotide N3′→P5′ phosphoramidates are promising candidates for antisense therapeutics, as well as for diagnostic applications. We recently reported…”
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Capillary gel electrophoresis and antisense therapeutics analysis of DNA analogs by DeDionisio, Lawrence A., Lloyd, David H.

“…Capillary gel electrophoresis (CGE) has become an effective tool for the analysis of antisense oligonucleotides. As these compounds begin to show promise in…”
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Analysis of an oligonucleotide N3'-->P5' phosphoramidate/phosphorothioate chimera with capillary gel electrophoresis by DeDionisio, L A, Raible, A M, Nelson, J S

“…N3'-->P5' phosphoramidate/phosphorothioate chimeric oligonucleotides (ODNs) are presently under investigation as potential antisense drugs. Within the field of…”
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The detection of oligonucleotide N3'-->P5' phosphoramidate/RNA duplexes with capillary gel electrophoresis by DeDionisio, L, Raible, A M, Gryaznov, S M

“…Oligonucleotide N3'-->P5' phosphoramidates (3'-phosphoramidates) are DNA analogs that are presently under investigation as potential therapeutic agents. These…”
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Effect of phosphorothioate modification of oligodeoxynuleotides on specific protein binding by Brown, DA, Kang, Shin-Heh, Gryaznov, S M, DeDionisio, L, Heidenreich, O, Sullivan, S, Xu, Xiao, Nerenberg, MI

“…Phosphorothioate modification of internucleoside linkages is widely used to prevent degradation of oligodeoxynucleotide (ODN) therapeutic agents in serum and…”
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Analysis of a ribonuclease H digestion of N3′ → P5′ phosphoramidate-RNA duplexes by capillary gel electrophoresis by DeDionisio, Lawrence, Gryaznov, Sergei M.

“…Phosphodiester oligonucleotides (ODNs) and their analogs are presently being investigated as potential antisense therapeutics in the treatment of viral…”
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An improved synthesis of oligodeoxynucleotide N3' arrow right P5' phosphoramidates and their chimera using hindered phosphoramidite monomers and a novel handle for reverse phase purification by Fearon, K L, Hirschbein, B L, Nelson, J S, Foy, M F, Nguyen, M Q, Okruszek, A, McCurdy, S N, Frediani, JE, DeDionisio, LA, Raible, A M, Cagle, EN, Boyd, V

“…Oligodeoxynucleotide N3' arrow right P5' phosphoramidates are promising candidates for antisense therapeutics, as well as for diagnostic applications. We…”
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Oligonucleotide N3' arrow right P5' phosphoramidates by Gryaznov, S M, Lloyd, D H, Chen, Jer-Kang, Schultz, R G, DeDionisio, LA, Ratmeyer, L, Wilson, W D

“…Synthetic oligonucleotides and their analogs have attracted considerable interest recently. These compounds may lead to highly specific therapeutic agents, as…”
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