Search Results - "DeCarlo Massaro, Gloria"

Calorie-related rapid onset of alveolar loss, regeneration, and changes in mouse lung gene expression by Massaro, Donald, Massaro, Gloria DeCarlo, Baras, Alex, Hoffman, Eric P, Clerch, Linda Biadasz

“…Calorie restriction, followed by ad libitum refeeding, results, respectively, in loss and regeneration of pulmonary alveoli. We now show 35% of alveoli are…”
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Lung Development, Lung Function, and Retinoids by Massaro, Donald, DeCarlo Massaro, Gloria

“…In this issue of the Journal, Checkley et al. report that, in a region with endemic vitamin A (retinol) deficiency, children whose mothers had received vitamin…”
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Developmental alveologenesis: longer, differential regulation and perhaps more danger by Massaro, Donald, Massaro, Gloria DeCarlo

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Estrogen regulates pulmonary alveolar formation, loss, and regeneration in mice by Massaro, Donald, Massaro, Gloria Decarlo

“…Lung tissue elastic recoil and the dimension and number of pulmonary gas-exchange units (alveoli) are major determinants of gas-exchange function. Loss of…”
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Estrogen receptor regulation of pulmonary alveolar dimensions: alveolar sexual dimorphism in mice by Massaro, Donald, Massaro, Gloria Decarlo

“…Female rats and mice have smaller and, per body mass (BM), more alveoli and alveolar surface area (Sa) than males of their respective species. This sexual…”
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Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice by Massaro, Donald, Massaro, Gloria Decarlo, Clerch, Linda Biadasz

“…A technically easy, noninvasive means of delivering molecules to alveoli, which act selectively or specifically in the lung, would be experimentally and…”
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Hunger disease and pulmonary alveoli by Massaro, Donald, Massaro, Gloria DeCarlo

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DNA microarray analysis of neonatal mouse lung connects regulation of KDR with dexamethasone-induced inhibition of alveolar formation by Clerch, Linda Biadasz, Baras, Alex S, Massaro, Gloria DeCarlo, Hoffman, Eric P, Massaro, Donald

“…Treatment of newborn mice with dexamethasone (Dex) inhibits the subdivision of lung saccules to form alveoli; treatment with all-trans retinoic acid (RA)…”
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Developmental Alveologenesis: New Roles for ApoE and LDL Receptor by Massaro, Donald, Massaro, Gloria Decarlo

“…Pulmonary developmental alveologenesis occurs, in substantial part, by subdivision (septation) of the gas-exchange saccules of the morphologically immature…”
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Estrogen receptor-alpha regulates pulmonary alveolar loss and regeneration in female mice: morphometric and gene expression studies by Massaro, Donald, Clerch, Linda Biadasz, Massaro, Gloria DeCarlo

“…Pulmonary alveoli, especially in females, are estrogen-responsive structures: ovariectomy in wild-type (WT) adult mice results in alveolar loss, and estradiol…”
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Apoetm1Unc mice have impaired alveologenesis, low lung function, and rapid loss of lung function by Massaro, Donald, Massaro, Gloria DeCarlo

“…Diminished lung function, indicated by a low forced expiratory volume in one second (FEV1), and short physical stature, predict early mortality from all…”
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Retinoic acid receptor-alpha regulates pulmonary alveolus formation in mice after, but not during, perinatal period by Massaro, Gloria DeCarlo, Massaro, Donald, Chambon, Pierre

“…The formation of pulmonary alveoli in mice and rats by subdivision of alveolar saccules that constitute the newborn's gas-exchange region ends by approximately…”
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Rapid onset of gene expression in lung, supportive of formation of alveolar septa, induced by refeeding mice after calorie restriction by Massaro, Donald, Alexander, Emma, Reiland, Kristin, Hoffman, Eric P, Massaro, Gloria DeCarlo, Clerch, Linda Biadasz

“…Alveolar regenerative gene expression is unidentified partly because its onset, after a regenerative stimulus, is unknown. Toward addressing this void, we used…”
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Lung retinol storing cells synthesize and secrete retinoic acid, an inducer of alveolus formation by Dirami, Ghenima, Massaro, Gloria DeCarlo, Clerch, Linda Biadasz, Ryan, Una S, Reczek, Peter R, Massaro, Donald

“…Retinoids play a key role in the formation of pulmonary alveoli. Lipid interstitial cells (LICs) of the alveolar wall store retinol and are concentrated at…”
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Critical period for alveologenesis and early determinants of adult pulmonary disease by Massaro, Donald, Massaro, Gloria DeCarlo

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Retinoids, alveolus formation, and alveolar deficiency: clinical implications by Massaro, Donald, Massaro, Gloria DeCarlo

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Transcriptional Programs in Murine Lung Regeneration by Clerch, Linda Biadasz, Massaro, Gloria DeCarlo, Massaro, Donald

“…Estrogen (E) treatment leads to lung regeneration in female mice that have lost alveoli and alveolar surface area due to ovariectomy. Gene profiling by…”
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Lung alveoli: endogenous programmed destruction and regeneration by Massaro, Gloria DeCarlo, Radaeva, Svetlana, Clerch, Linda Biadasz, Massaro, Donald

“…Mammalian alveoli, complex architectural and cellular units with dimensions that are linked to the organism's O2 consumption (VO2), are thought to be destroyed…”
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Expression of lung uncoupling protein-2 mRNA is modulated developmentally and by caloric intake by Xiao, Hong, Massaro, Donald, Massaro, Gloria DeCarlo, Clerch, Linda Biadasz

“…Lung expresses a high concentration of uncoupling protein-2 (UCP-2) mRNA, but neither its pulmonary regulation nor function is known. We measured lung UCP-2…”
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Gene Expression in Lung: Early Response to Ad Libitum Refeeding after Calorie Restriction in Adult Mice by Massaro, Donald, Reiland, Kristin, Alexander, Emma, Massaro, Gloria DeCarlo, Clerch, Linda Biadasz

“…Our goal is to identify and manipulate for therapeutic purposes gene expression in lung that is determinative of alveolar regeneration. One obstacle toward…”
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