Search Results - "DeBrosse, C. W"

A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent method by Fletcher, M H, Burns-Lynch, C E, Knouse, K W, Abraham, L T, DeBrosse, C W, Wuest, W M

“…Our efforts to develop a scalable and divergent synthesis of cyclic di-nucleotide analog precursors have resulted in (1) an orthogonally protected di-amino…”
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Quality of life in paediatric eosinophilic oesophagitis: what is important to patients? by Franciosi, J. P., Hommel, K. A., DeBrosse, C. W., Greenberg, A. B., Greenler, A. J., Abonia, J. P., Rothenberg, M. E., Varni, J. W.

“…Background and aims  Current research outcomes in paediatric eosinophilic oesophagitis (EoE) are directed towards histological improvement with no attention to…”
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New Leukotriene B4 Receptor Antagonist: Leucettamine A and Related Imidazole Alkaloids from the Marine Sponge Leucetta microraphis by Chan, George W, Mong, Seymour, Hemling, Mark E, Freyer, Alan J, Offen, Priscilla H, DeBrosse, Charles W, Sarau, Henry M, Westley, John W

“…Three new imidazole alkaloids, leucettamines A [1] and B [2] and leucettamidine [3], have been isolated from the Palauan sponge Leucetta microraphis. Their…”
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Lithium quadrupole coupling constants and the structures of organic lithium compounds in solution by Jackman, Lloyd M, Scarmoutzos, L. M, DeBrosse, C. W

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Aggregation of lithium phenolates in weakly polar aprotic solvents by Jackman, Lloyd M, DeBrosse, C. W

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Novel phloroglucinols from the plant Melicope sessiliflora (Rutaceae) by CHAN, J. A, SHULTIS, E. A, WESTLEY, J. W, CARR, S. A, DEBROSSE, C. W, EGGLESTON, D. S, FRANCIS, T. A, HYLAND, L. J, JOHNSON, W. P, KILLMER, L. B, STAIGER, D. B

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Heterobimetallic phosphido-bridged complexes containing coordinatively unsaturated rhodium(I) and iridium(I) centers. Structural characterization of FeIr(.mu.-PPh2)(CO)5(PPh3)2 by Roberts, David A, Steinmetz, Guy R, Breen, Michael J, Shulman, Peter M, Morrison, Eric D, Duttera, Michael R, DeBrosse, C. W, Whittle, Robert R, Geoffroy, Gregory L

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Synthesis, conformation, and dopaminergic activity of 5,6-ethano-bridged derivatives of selective dopaminergic 3-benzazepines by Weinstock, Joseph, Oh, Hye Ja, DeBrosse, Charles W, Eggleston, Drake S, Wise, Margaret, Flaim, Kathryn E, Gessner, George W, Sawyer, John L, Kaiser, Carl

“…To probe the suggestion that D-1 (DA1) dopamine receptors might possess an accessory pi-binding site in a location complementary to a suitably oriented…”
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Allergy and eosinophil-associated gastrointestinal disorders (EGID) by DeBrosse, Charles W, Rothenberg, Marc E

“…Eosinophil-associated gastrointestinal disorders (EGIDs) are characterized by an inappropriate accumulation of eosinophils within the gastrointestinal tract…”
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Carbamoyl-phosphate synthetase II of the mammalian CAD protein: kinetic mechanism and elucidation of reaction intermediates by positional isotope exchange by Meek, Thomas D, Karsten, William E, DeBrosse, Charles W

“…The kinetic mechanism of carbamoyl-phosphate synthetase II from Syrian hamster kidney cells has been determined at pH 7.2 and 37 degrees C. Initial velocity,…”
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3-Amino-2-piperidinone-6-carboxylic acid. Molecular structures of cis and trans benzoyl derivatives by Li, J P, Yellin, T O, Debrosse, C W, Eggleston, D S

“…The cis (2a) and trans (2b) isomers of methyl 3-benzamido-2-piperidinone-6-carboxylate (Apca) were prepared and separated by fractional recrystallizations…”
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A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent methodDedicated to Prof. Al Padwa, a scholar and a sportsman who has reached pinnacles in both science and sport, on the occasion of his 80th birthday.Electronic supplementary information (ESI) available. See DOI: 10.1039/c7ra06045a by Fletcher, M. H, Burns-Lynch, C. E, Knouse, K. W, Abraham, L. T, DeBrosse, C. W, Wuest, W. M

“…Our efforts to develop a scalable and divergent synthesis of cyclic di-nucleotide analog precursors have resulted in (1) an orthogonally protected di-amino…”
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A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent method† †Dedicated to Prof. Al Padwa, a scholar and a sportsman who has reached pinnacles in both science and sport, on the occasion of his 80th birthday. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7ra06045a Click here for additional data file by Fletcher, M. H., Burns-Lynch, C. E., Knouse, K. W., Abraham, L. T., DeBrosse, C. W., Wuest, W. M.

“…Herein we present a scalable and divergent synthesis of cyclic di-nucleotide analog precursors facilitated by differentiated di-amino sugars and a Staudinger…”
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Novel phloroglucinols from the plant Melicope sessilifloro (Rutaceae) by Chan, J. A, Shultis, E. A, Carr, S. A, DeBrosse, C. W, Eggleston, D. S, Francis, T. A, Hyland, L. J, Johnson, W. P, Killmer, L. B

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Conioidines A and B, Novel DNA-interacting Pyrrolidines from Chamaesaracha conioides by Chan, George W, Berry, David, DeBrosse, Charles W, Houling, Mark E, MacKenzie-LoCasto, Laurie, Offen, Priscilla H, Westley, John W

“…Two novel pyrrolidine compounds, conioidines A [1] and B [2], have been isolated from the Texas plant, Chamaesaracha conioides (Solanaceae). Their structures…”
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Chlorocardicin, a monocyclic beta-lactam from a Streptomyces sp. II. Isolation, physico-chemical properties and structure determination by Chan, J A, Shultis, E A, Dingerdissen, J J, DeBrosse, C W, Roberts, G D, Snader, K M

“…Chlorocardicin, a novel monocyclic beta-lactam, was isolated from the fermentation broth of a Streptomyces sp. by the use of non-ionic porous resin and reverse…”
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1,3-Diarylindan-2-carboxylic Acids, Potent and Selective Non-Peptide Endothelin Receptor Antagonists by Elliott, John D, Lago, M. Amparo, Cousins, Russell D, Gao, Aiming, Leber, Jack D, Erhard, Karl F, Nambi, Ponnal, Elshourbagy, Nabil A, Kumar, Chandrika

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A covalent nicotinamide adenine dinucleotide intermediate in the urocanase reaction by Matherly, L H, DeBrosse, C W, Phillips, A T

“…When imidazolepropionate, a competitive inhibitor of the nicotinamide adenine dinucleotide (NAD) dependent urocanase from Pseudomonas putida , binds to the…”
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Retrospective Identification of a Unique Cohort of Patients with Eosinophilic Esophagitis by DeBrosse, C.W, Buckmeier, B, Franciosi, J, Collins, M, Putnam, P, Rothenberg, M

“…Chart review revealed that these patients ranged from 6 months to 21 years of age. 71% of these patients were male (N = 15/21) and 40% (N = 6/15) had a…”
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A study of variable hydration states in topotecan hydrochloride by Vogt, Frederick G., Dell’Orco, Philip C., Diederich, Ann. M., Su, Qiaogong, Wood, Jeffery L., Zuber, Gary E., Katrincic, Lee M., Mueller, Ronald L., Busby, David J., DeBrosse, Charles W.

“…Topotecan hydrochloride, a pharmaceutical compound developed as a treatment for cancer, exhibits variable hydration states in a crystalline solid form chosen…”
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