Search Results - "DeBlasio, Richelle"
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Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients
Published in Science (American Association for the Advancement of Science) (05-02-2021)“…Anti-programmed cell death protein 1 (PD-1) therapy provides long-term clinical benefits to patients with advanced melanoma. The composition of the gut…”
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Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1
Published in Nature medicine (01-03-2022)“…Ample evidence indicates that the gut microbiome is a tumor-extrinsic factor associated with antitumor response to anti-programmed cell death protein-1 (PD-1)…”
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The Combined Roles of Race/Ethnicity and Substance Use in Predicting Likelihood of Kidney Transplantation
Published in Transplantation (01-04-2022)“…Racial/ethnic minorities face known disparities in likelihood of kidney transplantation. These disparities may be exacerbated when coupled with ongoing…”
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Tim-3 mediates T cell trogocytosis to limit antitumor immunity
Published in The Journal of clinical investigation (01-05-2022)“…T cell immunoglobulin mucin domain-containing protein 3 (Tim-3) negatively regulates innate and adaptive immunity in cancer. To identify the mechanisms of…”
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303 Phase II trial of neoadjuvant nivolumab (Nivo) and intra-tumoral (IT) CMP-001 in high-risk resectable melanoma (Neo-C-Nivo): final results
Published in Journal for immunotherapy of cancer (01-11-2020)“…BackgroundNeoadjuvant PD-1 blockade produces major pathological responses (MPR) in ~30% of patients (pts) with high-risk resectable melanoma (MEL) with durable…”
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How Can Pharmacists Support STI Prevention and Treatment Among Female Adolescents and Young Adults?
Published in Innovations in pharmacy (11-04-2017)“…Sexual and reproductive health is a critical focus area for adolescents and young adults (AYAs). Of the 20 million newly diagnosed Sexually Transmitted…”
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IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma
Published in Clinical cancer research (15-10-2020)“…Natural killer (NK) cells play a critical role in tumor immunosurveillance. Multiple activating and inhibitory receptors (IR) regulate NK-cell-mediated tumor…”
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The Combined Roles of Race/Ethnicity and Substance Use in Predicting Likelihood of Kidney Transplantation
Published in Transplantation (07-02-2022)Get full text
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IL-15 stimulation with TIGIT blockade reverses CD155-mediated NK cell dysfunction in melanoma
Published in Clinical cancer research (26-06-2020)Get full text
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Abstract LB062: Efficacy of Responder-derived Fecal Microbiota Transplant (R-FMT) and Pembrolizumab in Anti-PD-1 Refractory Patients with Advanced Melanoma
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Background: Monoclonal antibodies (mAb) targeting the programmed cell death protein 1 (PD-1) receptor provide durable long-term benefit in a subset of…”
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